DE2858357C2 - - Google Patents

Info

Publication number
DE2858357C2
DE2858357C2 DE2858357A DE2858357A DE2858357C2 DE 2858357 C2 DE2858357 C2 DE 2858357C2 DE 2858357 A DE2858357 A DE 2858357A DE 2858357 A DE2858357 A DE 2858357A DE 2858357 C2 DE2858357 C2 DE 2858357C2
Authority
DE
Germany
Prior art keywords
dna
mrna
cdna
sequence
nucleotide sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE2858357A
Other languages
German (de)
English (en)
Inventor
William J. Rutter
Howard Michael Goodman
Axel San Francisco Calif. Us Ullrich
John Curtin Au Shine
John Mitchell Chirgwin
Raymond Louis Pictet
Peter Horst San Francisco Calif. Us Seeburg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
Original Assignee
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05897710 external-priority patent/US4363877B1/en
Priority claimed from US05/898,887 external-priority patent/US4264731A/en
Application filed by University of California Berkeley filed Critical University of California Berkeley
Application granted granted Critical
Publication of DE2858357C2 publication Critical patent/DE2858357C2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57518—Placental lactogen; Chorionic somatomammotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE2858357A 1977-05-27 1978-05-24 Expired - Lifetime DE2858357C2 (enrdf_load_html_response)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US80134377A 1977-05-27 1977-05-27
US80502377A 1977-06-09 1977-06-09
US89770978A 1978-04-19 1978-04-19
US05897710 US4363877B1 (en) 1977-09-23 1978-04-19 Recombinant dna transfer vectors
US05/898,887 US4264731A (en) 1977-05-27 1978-04-21 DNA Joining method
US89900278A 1978-04-26 1978-04-26
US89900378A 1978-04-26 1978-04-26

Publications (1)

Publication Number Publication Date
DE2858357C2 true DE2858357C2 (enrdf_load_html_response) 1990-03-15

Family

ID=27569921

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782822568 Granted DE2822568A1 (de) 1977-05-27 1978-05-24 Dns-transfer-vektor und ein gen eines hoeheren organismus enthaltender mikroorganismus
DE2858357A Expired - Lifetime DE2858357C2 (enrdf_load_html_response) 1977-05-27 1978-05-24

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19782822568 Granted DE2822568A1 (de) 1977-05-27 1978-05-24 Dns-transfer-vektor und ein gen eines hoeheren organismus enthaltender mikroorganismus

Country Status (21)

Country Link
JP (1) JPH0659218B2 (enrdf_load_html_response)
AR (1) AR225404A1 (enrdf_load_html_response)
AU (1) AU521903B2 (enrdf_load_html_response)
BE (1) BE867424A (enrdf_load_html_response)
BG (1) BG40319A3 (enrdf_load_html_response)
CH (1) CH642680A5 (enrdf_load_html_response)
DD (1) DD145927A5 (enrdf_load_html_response)
DE (2) DE2822568A1 (enrdf_load_html_response)
DK (2) DK233278A (enrdf_load_html_response)
FI (1) FI64640C (enrdf_load_html_response)
FR (1) FR2392033B1 (enrdf_load_html_response)
GB (1) GB1565190A (enrdf_load_html_response)
GR (1) GR73552B (enrdf_load_html_response)
IL (1) IL54790A (enrdf_load_html_response)
IT (1) IT1094934B (enrdf_load_html_response)
LU (1) LU79714A1 (enrdf_load_html_response)
NL (1) NL7805591A (enrdf_load_html_response)
NZ (1) NZ187300A (enrdf_load_html_response)
PL (1) PL140200B1 (enrdf_load_html_response)
PT (1) PT68082B (enrdf_load_html_response)
SE (4) SE451461B (enrdf_load_html_response)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA782933B (en) * 1977-09-23 1979-05-30 Univ California Purification of nucleotide sequences suitable for expression in bacteria
RO80052B (ro) * 1977-11-08 1985-03-30 Genetech Procedeu pentru prepararea unui vehicul recombinat de clonare pentru transformarea unei gazde bacteriene pentru a deveni generator de polipeptida heterologa
GR71912B (enrdf_load_html_response) * 1978-08-11 1983-08-16 Univ California
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
JPS55150883A (en) * 1979-05-11 1980-11-25 Nakano Vinegar Co Ltd Method of storing "mozuku"
GR68404B (enrdf_load_html_response) * 1979-06-01 1981-12-29 Univ California
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (enrdf_load_html_response) * 1979-09-12 1982-09-03 Univ California
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
IL61982A (en) * 1980-02-15 1984-01-31 Cpc International Inc Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
ATE22327T1 (de) * 1980-12-12 1986-10-15 Unilever Nv Dna-sequenzen fuer verschiedene allele formen des reifen thaumatins, diese sequenzen enthaltende rekombinante plasmide, verfahren zur herstellung dieser plasmide, diese rekombinante plasmide enthaltende bakterielle kulturen und verfahren zur herstellung von reifen thaumatin.
CA1193207A (en) * 1980-12-12 1985-09-10 Cornelis T. Verrips Structural genes encoding the various allelic maturation forms of preprothaumatin, recombinant cloning vehicles, comprising said structural genes and expression thereof in transformed microbial host cells
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
EP0103395A3 (en) * 1982-08-17 1985-05-22 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
DE4034702A1 (de) * 1990-10-31 1992-05-07 Siemens Ag Verfahren und vorrichtung zur pruefung der aktiven werkzeuge von gesenkbiegemaschinen, insbesondere von biegestempeln

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
International Journal of Peptide Research 4: 281-287, (1972) *

Also Published As

Publication number Publication date
SE455794B (sv) 1988-08-08
GB1565190A (en) 1980-04-16
DK791A (da) 1991-01-04
CH642680A5 (en) 1984-04-30
SE7806086L (sv) 1978-11-28
NZ187300A (en) 1982-08-17
SE8305327L (sv) 1983-09-29
IT1094934B (it) 1985-08-10
NL7805591A (nl) 1978-11-29
AU521903B2 (en) 1982-05-06
JPH0659218B2 (ja) 1994-08-10
DK791D0 (da) 1991-01-04
FI64640C (fi) 1983-12-12
GR73552B (enrdf_load_html_response) 1984-03-14
PT68082B (en) 1980-02-20
BE867424A (fr) 1978-09-18
FR2392033A1 (fr) 1978-12-22
FI64640B (fi) 1983-08-31
SE8305327D0 (sv) 1983-09-29
PL140200B1 (en) 1987-04-30
IT7823930A0 (it) 1978-05-29
PT68082A (en) 1978-06-01
AR225404A1 (es) 1982-03-31
AU3648878A (en) 1979-11-29
FI781675A7 (fi) 1978-11-28
DK233278A (da) 1978-11-28
LU79714A1 (fr) 1978-11-06
FR2392033B1 (fr) 1985-09-13
BG40319A3 (bg) 1986-11-14
DE2822568C2 (enrdf_load_html_response) 1989-08-31
IL54790A (en) 1983-07-31
SE8305328L (sv) 1983-09-29
SE8305329L (sv) 1983-09-29
SE451461B (sv) 1987-10-12
SE8305328D0 (sv) 1983-09-29
JPS5449387A (en) 1979-04-18
IL54790A0 (en) 1978-07-31
DE2822568A1 (de) 1978-12-14
PL207176A1 (pl) 1979-03-26
SE8305329D0 (sv) 1983-09-29
DD145927A5 (de) 1981-01-14

Similar Documents

Publication Publication Date Title
DE2858357C2 (enrdf_load_html_response)
DE3111405C2 (enrdf_load_html_response)
DE3588168T2 (de) Apoaequorin Peptide, rekombinante DNS-Vektoren fähig zu deren Expression und diese Vektoren enthaltende Mikroorganismen
DE3050722C2 (enrdf_load_html_response)
DE3785864T2 (de) Verfahren zur Herstellung von menschlichem Epidermalwachstumsfaktor und dessen Analogen.
DE3650553T2 (de) Verfahren zur Herstellung biologisch aktiver Rinder- und Schweine-Wachstumshormone und Mischung mit biologisch aktivem Schweine-Wachstumshormon
DD147369A5 (de) Verfahren zur synthese eines eukaryontischen proteins durch mikroorganismen
DD212532A5 (de) Verfahren zur stabilisierung und selektion von wirtszellen, die rekombinierende dna enthalten
DD154022A5 (de) Verfahren zur herstellung von menschlichem pre-wachstumshormon
CH663032A5 (de) Doppelstraengige dna, replizierbare plasmidische expressionstraeger zur mikrobiellen herstellung von hybrid human-leukozyten-interferon und transformierte mikroorganismen.
DD219212A5 (de) Verfahren zur herstellung eines rekombinanten dna-klonierungsvektors
DD208989A5 (de) Verfahren zur synthetisierung von menschlichem insulin
DD153393A5 (de) Verfahren zur reinigung von nucleotidsequenzen
EP0136472B1 (de) Herstellung von Sekretin
AT386609B (de) Verfahren zum herstellen eines mikroorganismus
AT386607B (de) Verfahren zum herstellen eines dns-transfer-vektors
EP0393039B1 (en) Process for producing peptides by specific cleavage of fusion proteins with collagenases obtained by genetic engineering
AT386608B (de) Verfahren zum herstellen eines mikroorganismus
DE69920470T2 (de) Neuartiges gen und transformant, welcher dieses beinhaltet
EP0214548B1 (de) DNA-Sequenzen, rekombinante DNA-Moleküle und Verfahren zur Herstellung des Enzyms Mutarotase aus Acinetobacter calcoaceticus
DE3102721C2 (enrdf_load_html_response)
DE3220333C2 (enrdf_load_html_response)
DD154023A5 (de) Verfahren zur herstellung eines dns-transfer-vektors
AT389890B (de) Verfahren zur herstellung von humaninsulin
AT389891B (de) Verfahren zur herstellung von menschlichem proinsulin

Legal Events

Date Code Title Description
Q172 Divided out of (supplement):

Ref country code: DE

Ref document number: 2822568

8110 Request for examination paragraph 44
8181 Inventor (new situation)

Free format text: RUTTER, WILLIAM J. GOODMAN, HOWARD MICHAEL ULLRICH, AXEL, SAN FRANCISCO, CALIF., US SHINE, JOHN, CURTIN, AU CHIRGWIN, JOHN MITCHELL PICTET, RAYMOND LOUIS SEEBURG, PETER HORST, SAN FRANCISCO, CALIF., US

AC Divided out of

Ref country code: DE

Ref document number: 2822568

Format of ref document f/p: P

AC Divided out of

Ref country code: DE

Ref document number: 2822568

Format of ref document f/p: P

D2 Grant after examination
8364 No opposition during term of opposition