DE2709500C2 - Verfahren zur Reinigung von Heparin - Google Patents

Verfahren zur Reinigung von Heparin

Info

Publication number
DE2709500C2
DE2709500C2 DE2709500A DE2709500A DE2709500C2 DE 2709500 C2 DE2709500 C2 DE 2709500C2 DE 2709500 A DE2709500 A DE 2709500A DE 2709500 A DE2709500 A DE 2709500A DE 2709500 C2 DE2709500 C2 DE 2709500C2
Authority
DE
Germany
Prior art keywords
heparin
gel
matrix
antithrombin
bound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2709500A
Other languages
German (de)
English (en)
Other versions
DE2709500A1 (de
Inventor
Lars-Olov Knivsta Andersson
Erik Yngve Dipl.-Phys. Bromma Holmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
KABI STOCKHOLM SE AB
Kabi AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KABI STOCKHOLM SE AB, Kabi AB filed Critical KABI STOCKHOLM SE AB
Publication of DE2709500A1 publication Critical patent/DE2709500A1/de
Application granted granted Critical
Publication of DE2709500C2 publication Critical patent/DE2709500C2/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE2709500A 1976-03-05 1977-03-04 Verfahren zur Reinigung von Heparin Expired DE2709500C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7603040A SE431218B (sv) 1976-03-05 1976-03-05 Forfarande for rening av heparin

Publications (2)

Publication Number Publication Date
DE2709500A1 DE2709500A1 (de) 1977-09-08
DE2709500C2 true DE2709500C2 (de) 1986-09-18

Family

ID=20327240

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2709500A Expired DE2709500C2 (de) 1976-03-05 1977-03-04 Verfahren zur Reinigung von Heparin

Country Status (21)

Country Link
JP (1) JPS52108012A (ru)
AT (1) AT356818B (ru)
AU (1) AU508430B2 (ru)
CA (1) CA1079272A (ru)
CS (1) CS196349B2 (ru)
DE (1) DE2709500C2 (ru)
DK (1) DK155606C (ru)
ES (1) ES456196A1 (ru)
FI (1) FI62103C (ru)
FR (1) FR2342991A1 (ru)
GB (1) GB1539332A (ru)
HU (1) HU176811B (ru)
IE (1) IE44907B1 (ru)
IL (1) IL51346A (ru)
NL (1) NL186385C (ru)
NO (1) NO144388C (ru)
NZ (1) NZ183480A (ru)
PL (1) PL103049B1 (ru)
SE (1) SE431218B (ru)
SU (1) SU736860A3 (ru)
ZA (1) ZA771267B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE449753B (sv) * 1978-11-06 1987-05-18 Choay Sa Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav
DE3531101A1 (de) * 1984-08-31 1986-03-13 Nicolás Huberto Olivos Behrens Ein nicht thrombenbildendes heparin und ein verfahren zu seiner gewinnung
US9676816B2 (en) * 2014-01-21 2017-06-13 Board Of Trustees Of The University Of Arkansas Heparin affinity tag and applications thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2623001A (en) * 1949-04-07 1952-12-23 Bengt E G V Sylven Preparing heparin
DE1195010B (de) * 1962-05-12 1965-06-16 Ormonoterapia Richter S P A Verfahren zur Reinigung von Heparin nach der Chromatographischen Methode

Also Published As

Publication number Publication date
IL51346A (en) 1979-11-30
DK155606C (da) 1989-09-11
IE44907L (en) 1977-09-05
FI770491A (ru) 1977-09-06
ES456196A1 (es) 1978-07-01
IL51346A0 (en) 1977-03-31
DK155606B (da) 1989-04-24
FI62103B (fi) 1982-07-30
GB1539332A (en) 1979-01-31
AT356818B (de) 1980-05-27
PL103049B1 (pl) 1979-05-31
NL186385B (nl) 1990-06-18
SE7603040L (sv) 1977-09-06
DK96077A (da) 1977-09-06
AU508430B2 (en) 1980-03-20
FR2342991A1 (fr) 1977-09-30
ATA144577A (de) 1979-10-15
NO770764L (no) 1977-09-06
CS196349B2 (en) 1980-03-31
CA1079272A (en) 1980-06-10
NL7701882A (nl) 1977-09-07
NO144388C (no) 1981-08-19
FI62103C (fi) 1982-11-10
IE44907B1 (en) 1982-05-19
JPS52108012A (en) 1977-09-10
NO144388B (no) 1981-05-11
SE431218B (sv) 1984-01-23
AU2295377A (en) 1978-09-07
HU176811B (en) 1981-05-28
NL186385C (nl) 1990-11-16
SU736860A3 (ru) 1980-05-25
NZ183480A (en) 1979-08-31
FR2342991B1 (ru) 1981-10-30
ZA771267B (en) 1978-01-25
DE2709500A1 (de) 1977-09-08

Similar Documents

Publication Publication Date Title
DE68922358T2 (de) Chromatographische Trennung von Plasmaproteinen, insbesondere von Faktor VIII, von Willebrand Faktor, von Fibronectin und von Fibrinogen.
DE2417619C2 (de) Intramolekular vernetztes Hämoglobin, Verfahren zu dessen Herstellung und seine Verwendung
DE2839170C2 (de) Chromatographisches Material
DE2322552C2 (de) Verfahren zum Abtrennen von Protein A aus Staphylococcus aureus aus einer Flüssigkeit
DE2243688B2 (de) Verfahren zur Isolierung von Antithrombin
DE3346336C2 (ru)
DE69002427T2 (de) Verfahren zur Herstellung eines Konzentrats des Faktor VIII-von Willebrand-Faktor-Komplexes der Blutgerinnung aus Vollplasma.
EP0409053B1 (de) Verfahren zur Reinigung von Annexinen
DE2711773A1 (de) Verfahren zur reinigung und isolierung von hepatitisvirus zur herstellung eines impfstoffes
EP1005492A1 (de) Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
DE69125764T2 (de) Verfahren zur Herstellung des Von Willebrand-Faktors von höchster Reinheit
DE1054405B (de) Verfahren zur Gewinnung von Urokinasekonzentraten
CH628246A5 (de) Verfahren zur herstellung eines schuetzenden pertussis-antigens.
EP0457371A1 (de) Verfahren zur Gewinnung des Gewebeproteins PP4
DE68908426T2 (de) Adjuvanz für Krebsimmuntherapie.
DE3787996T2 (de) Heparine, frei von E.D.T.A., Fraktionen und Fragmente von Heparin, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten.
DE2551966C3 (de) Verfahren zum Reinigen von Urokinase
DE2709500C2 (de) Verfahren zur Reinigung von Heparin
EP0307002A1 (de) Verfahren zur Herstellung eines Antithrombin III-Konzentrates
EP1326893A2 (de) Bikunin enthaltende plasmafraktion, verfahren zu ihrer herstellung und ihrer verwendung
EP0049861B1 (de) Thrombininhibitor, seine Herstellung und Verwendung
DE3724726A1 (de) Verfahren zur reinigung des plazentaren gewebeproteins pp4
CH643861A5 (de) Verfahren zum reinigen eines gamma-globulinderivats.
DE2448371A1 (de) Verfahren zur isolierung der transferrine aus biologischen stoffen
DE2428955C3 (de) Verfahren zur Abtrennung der enzymatischen Komponente mit in vivo antikoagulierender und in vitro koagulierender Wirkung aus dem Gift der Schlange Ancistrodon rhodostoma und daraus hergestellte Mittel

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: KABI PHARMACIA AB, UPPSALA, SE

8328 Change in the person/name/address of the agent

Free format text: FRHR. VON PECHMANN, E., DIPL.-CHEM. DR.RER.NAT. BEHRENS, D., DR.-ING. GOETZ, R., DIPL.-ING. DIPL.-WIRTSCH.-ING., PAT.-ANWAELTE, 8000 MUENCHEN