DE2537070A1 - Thiazinderivate - Google Patents
ThiazinderivateInfo
- Publication number
- DE2537070A1 DE2537070A1 DE19752537070 DE2537070A DE2537070A1 DE 2537070 A1 DE2537070 A1 DE 2537070A1 DE 19752537070 DE19752537070 DE 19752537070 DE 2537070 A DE2537070 A DE 2537070A DE 2537070 A1 DE2537070 A1 DE 2537070A1
- Authority
- DE
- Germany
- Prior art keywords
- methyl
- hydroxy
- thiazine
- thieno
- dioxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Electroplating Methods And Accessories (AREA)
- Manufacturing Of Printed Wiring (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1158274A CH608500A5 (en) | 1974-08-26 | 1974-08-26 | Process for the preparation of thiazine derivatives |
CH1215774A CH608501A5 (en) | 1974-09-09 | 1974-09-09 | Process for the preparation of thiazine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2537070A1 true DE2537070A1 (de) | 1976-03-18 |
DE2537070C2 DE2537070C2 (fr) | 1987-06-25 |
Family
ID=25708582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19752537070 Granted DE2537070A1 (de) | 1974-08-26 | 1975-08-20 | Thiazinderivate |
Country Status (20)
Country | Link |
---|---|
JP (1) | JPS5826758B2 (fr) |
AR (1) | AR216288A1 (fr) |
AT (1) | AT350064B (fr) |
BR (1) | BR7505463A (fr) |
DD (1) | DD124119A5 (fr) |
DE (1) | DE2537070A1 (fr) |
DK (1) | DK137835B (fr) |
FI (1) | FI59253C (fr) |
FR (3) | FR2282893A1 (fr) |
GB (1) | GB1519811A (fr) |
HU (1) | HU173739B (fr) |
IE (1) | IE41457B1 (fr) |
IL (1) | IL47877A (fr) |
LU (2) | LU73257A1 (fr) |
NL (2) | NL183582C (fr) |
NO (1) | NO146096C (fr) |
PL (1) | PL106076B1 (fr) |
SE (1) | SE412066B (fr) |
SU (1) | SU603338A3 (fr) |
YU (1) | YU40266B (fr) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4187303A (en) | 1977-08-22 | 1980-02-05 | Hoffmann-La Roche Inc. | Thiazine derivatives |
EP0009142A1 (fr) * | 1978-09-02 | 1980-04-02 | Dr. Karl Thomae GmbH | 1,1-Dioxydes de 4-hydroxy-2H(1)benzothiéno(2,3-e)-1,2-thiazine-3-carboxamides et leurs sels, procédé de préparation et application |
EP0021058A2 (fr) * | 1979-06-13 | 1981-01-07 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés de la benzothiénothiazine, leur application, procédé et intermédiaires pour leur préparation et médicaments les contenant |
EP0103142A1 (fr) * | 1982-09-09 | 1984-03-21 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés de thiéno(2,3-e)-1,2-thiazine |
AT400437B (de) * | 1993-12-14 | 1995-12-27 | Chem Pharm Forsch Gmbh | Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung |
AT400568B (de) * | 1994-05-18 | 1996-01-25 | Chem Pharm Forsch Gmbh | Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung |
LT3947B (en) | 1988-02-18 | 1996-05-27 | Chem Pharm Forsch Gmbh | Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents |
US5538966A (en) * | 1994-01-21 | 1996-07-23 | Alcon Laboratories, Inc. | Carbonic anhydrase inhibitors |
US6613784B1 (en) | 1999-03-02 | 2003-09-02 | Nicox S.A. | Nitroxyderivatives having antinflammatory, analgesic and antithrombotic activity |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2704485A1 (de) * | 1977-02-03 | 1978-08-10 | Thomae Gmbh Dr K | Neue 2,5-dihydro-1,2-thiazino eckige klammer auf 5,6-b eckige klammer zu indol-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
ZA784958B (en) * | 1977-09-06 | 1979-08-29 | Hoffmann La Roche | Thiazine derivatives |
AU518216B2 (en) * | 1977-09-06 | 1981-09-17 | Hafslund Nycomed Pharma Aktiengesellschaft | Thienothiazine derivatives |
JPS58109492A (ja) * | 1981-12-22 | 1983-06-29 | Mitsui Toatsu Chem Inc | チエノチアジン誘導体およびそれを含有する医薬組成物 |
JPS60163533U (ja) * | 1984-04-02 | 1985-10-30 | ホシデン株式会社 | リ−ル台の制動装置 |
JPH0318748Y2 (fr) * | 1985-12-18 | 1991-04-19 | ||
EP0658559A1 (fr) * | 1993-12-14 | 1995-06-21 | Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. | Dérivés thiénothianine, procédé pour leur préparation et leur application comme inhibiteurs de 5-dipoxygenase et cyclooxygenase |
CN1171892C (zh) * | 2001-06-25 | 2004-10-20 | 李晶 | 具有抗炎镇痛活性的噻吩并噻嗪化合物及其制备方法和用途 |
-
1975
- 1975-08-05 IL IL47877A patent/IL47877A/xx unknown
- 1975-08-20 DE DE19752537070 patent/DE2537070A1/de active Granted
- 1975-08-22 AR AR260104A patent/AR216288A1/es active
- 1975-08-22 GB GB34943/75A patent/GB1519811A/en not_active Expired
- 1975-08-22 FR FR7525999A patent/FR2282893A1/fr active Granted
- 1975-08-25 IE IE1856/75A patent/IE41457B1/en not_active IP Right Cessation
- 1975-08-25 HU HU75HO1829A patent/HU173739B/hu unknown
- 1975-08-25 SU SU752167373A patent/SU603338A3/ru active
- 1975-08-25 DK DK381175AA patent/DK137835B/da not_active IP Right Cessation
- 1975-08-25 DD DD188010A patent/DD124119A5/xx unknown
- 1975-08-25 AT AT655975A patent/AT350064B/de active Protection Beyond IP Right Term
- 1975-08-25 SE SE7509446A patent/SE412066B/xx not_active IP Right Cessation
- 1975-08-26 NL NLAANVRAGE7510057,A patent/NL183582C/xx active Protection Beyond IP Right Term
- 1975-08-26 NO NO752932A patent/NO146096C/no unknown
- 1975-08-26 PL PL1975182921A patent/PL106076B1/pl unknown
- 1975-08-26 BR BR7505463*A patent/BR7505463A/pt unknown
- 1975-08-26 FI FI752398A patent/FI59253C/fi not_active IP Right Cessation
- 1975-08-26 YU YU2166/75A patent/YU40266B/xx unknown
- 1975-08-26 JP JP50102635A patent/JPS5826758B2/ja not_active Expired
- 1975-08-26 LU LU73257A patent/LU73257A1/xx active Protection Beyond IP Right Term
-
1976
- 1976-05-21 FR FR7615424A patent/FR2303803A1/fr active Granted
- 1976-05-21 FR FR7615425A patent/FR2309558A1/fr active Granted
-
1993
- 1993-06-16 LU LU88312C patent/LU88312I2/de unknown
- 1993-06-17 NL NL930080C patent/NL930080I2/nl unknown
Non-Patent Citations (1)
Title |
---|
J.Med.Chem., 16, 1973, 493 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4187303A (en) | 1977-08-22 | 1980-02-05 | Hoffmann-La Roche Inc. | Thiazine derivatives |
EP0009142A1 (fr) * | 1978-09-02 | 1980-04-02 | Dr. Karl Thomae GmbH | 1,1-Dioxydes de 4-hydroxy-2H(1)benzothiéno(2,3-e)-1,2-thiazine-3-carboxamides et leurs sels, procédé de préparation et application |
EP0021058A2 (fr) * | 1979-06-13 | 1981-01-07 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés de la benzothiénothiazine, leur application, procédé et intermédiaires pour leur préparation et médicaments les contenant |
EP0021058A3 (fr) * | 1979-06-13 | 1981-01-28 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés de la benzothiénothiazine, leur application, procédé et intermédiaires pour leur préparation et médicaments les contenant |
EP0103142A1 (fr) * | 1982-09-09 | 1984-03-21 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés de thiéno(2,3-e)-1,2-thiazine |
LT3947B (en) | 1988-02-18 | 1996-05-27 | Chem Pharm Forsch Gmbh | Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents |
AT400437B (de) * | 1993-12-14 | 1995-12-27 | Chem Pharm Forsch Gmbh | Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung |
US5538966A (en) * | 1994-01-21 | 1996-07-23 | Alcon Laboratories, Inc. | Carbonic anhydrase inhibitors |
AT400568B (de) * | 1994-05-18 | 1996-01-25 | Chem Pharm Forsch Gmbh | Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung |
US6613784B1 (en) | 1999-03-02 | 2003-09-02 | Nicox S.A. | Nitroxyderivatives having antinflammatory, analgesic and antithrombotic activity |
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH |
|
8328 | Change in the person/name/address of the agent |
Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT |