DE2519101A1 - Morpholinderivate - Google Patents

Morpholinderivate

Info

Publication number
DE2519101A1
DE2519101A1 DE19752519101 DE2519101A DE2519101A1 DE 2519101 A1 DE2519101 A1 DE 2519101A1 DE 19752519101 DE19752519101 DE 19752519101 DE 2519101 A DE2519101 A DE 2519101A DE 2519101 A1 DE2519101 A1 DE 2519101A1
Authority
DE
Germany
Prior art keywords
radical
stands
formula
compound
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19752519101
Other languages
German (de)
English (en)
Inventor
Allen John Guildford
Bernard Joseph Mcloughlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE2519101A1 publication Critical patent/DE2519101A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752519101 1974-05-07 1975-04-29 Morpholinderivate Ceased DE2519101A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2001374A GB1452701A (en) 1974-05-07 1974-05-07 Morpholine derivatives
JP2495676A JPS52139074A (en) 1974-05-07 1976-03-08 Morpholine derivative and mental version drug composition containing same

Publications (1)

Publication Number Publication Date
DE2519101A1 true DE2519101A1 (de) 1975-11-20

Family

ID=26254367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752519101 Ceased DE2519101A1 (de) 1974-05-07 1975-04-29 Morpholinderivate

Country Status (20)

Country Link
US (1) US4010266A (enExample)
JP (2) JPS50154273A (enExample)
AR (1) AR209436A1 (enExample)
AT (1) AT344188B (enExample)
BE (1) BE828822A (enExample)
CA (1) CA1067075A (enExample)
CH (2) CH610894A5 (enExample)
DD (1) DD121641A5 (enExample)
DE (1) DE2519101A1 (enExample)
DK (1) DK198675A (enExample)
FI (1) FI751344A7 (enExample)
FR (1) FR2269953B1 (enExample)
GB (1) GB1452701A (enExample)
HK (1) HK5580A (enExample)
IN (1) IN141021B (enExample)
KE (1) KE3021A (enExample)
LU (1) LU72408A1 (enExample)
NL (1) NL7505140A (enExample)
SE (1) SE425312B (enExample)
ZA (1) ZA752388B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007710A1 (en) * 1996-08-23 1998-02-26 Neurosearch A/S Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine d4 receptor antagonists

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088814A (en) * 1974-05-07 1978-05-09 Imperial Chemical Industries Limited Morpholine derivatives
JPS5266991U (enExample) * 1975-11-13 1977-05-18
AU508678B2 (en) * 1976-07-14 1980-03-27 Imperial Chemical Industries Limited Anorexiants
IE50355B1 (en) * 1979-10-20 1986-04-02 Wyeth John & Brother Ltd Morpholine derivatives
AU3364493A (en) * 1992-01-28 1993-09-01 Smithkline Beecham Plc Compounds as calcium channel antagonists
US6048859A (en) 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
IL112778A0 (en) * 1994-03-04 1995-05-26 Merck & Co Inc Substituted heterocycles, their preparation and pharmaceutical compositions containing them
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
EP1318988A2 (en) 2000-09-11 2003-06-18 Sepracor, Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2255077A (en) * 1938-03-21 1941-09-09 Du Pont Film Mfg Corp Filter dyes for color photography

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007710A1 (en) * 1996-08-23 1998-02-26 Neurosearch A/S Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine d4 receptor antagonists
US6207662B1 (en) 1996-08-23 2001-03-27 Neurosearch A/S Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine D4 receptor antagonists
US6479491B1 (en) 1996-08-23 2002-11-12 Neurosearch A/S Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine d4 receptor antagonists

Also Published As

Publication number Publication date
FR2269953A1 (enExample) 1975-12-05
BE828822A (fr) 1975-11-07
DK198675A (da) 1975-11-08
KE3021A (en) 1980-03-14
ATA341575A (de) 1977-11-15
CA1067075A (en) 1979-11-27
US4010266A (en) 1977-03-01
ZA752388B (en) 1976-03-31
FR2269953B1 (enExample) 1978-10-06
DD121641A5 (enExample) 1976-08-12
AT344188B (de) 1978-07-10
NL7505140A (nl) 1975-11-11
AR209436A1 (es) 1977-04-29
LU72408A1 (enExample) 1976-11-11
SE425312B (sv) 1982-09-20
AU8021575A (en) 1976-10-21
IN141021B (enExample) 1977-01-08
FI751344A7 (enExample) 1975-11-08
JPS52139074A (en) 1977-11-19
JPS50154273A (enExample) 1975-12-12
HK5580A (en) 1980-02-29
CH634569A5 (de) 1983-02-15
SE7505237L (sv) 1975-11-10
CH610894A5 (enExample) 1979-05-15
GB1452701A (en) 1976-10-13

Similar Documents

Publication Publication Date Title
CH616420A5 (enExample)
DE1518489A1 (de) Substituierte N-Cyclopropylaethylendiamine und Verfahren zu ihrer Herstellung
DE3145004A1 (de) 2-substituierte benzofuranderivate
DE2340874A1 (de) Morpholinderivate
CH634569A5 (de) Verfahren zur herstellung von morpholinderivaten.
DE69103087T2 (de) N-substituierte Trifluormethylphenyltetrahydropyridine, Verfahren zur Herstellung, Zwischenprodukte, sowie Arzneimittel, die solche enthalten.
DE2633889C2 (de) Neue Aminobenzocyclohepten-Derivate und deren Salze, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
DE2126559A1 (de) 2,2-Diaryl-4-piperidinbutyramide
DE2507429C2 (de) Aminosäureester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
AT345792B (de) Verfahren zur herstellung von neuen 1- disubstiuierten phenoxy-2-hydroxy-3-diphenylmethylamino- und - 3- (9'-fluorenylamino)-propanen sowie deren saeureadditionssalzen
DE1936206A1 (de) Diphenylmethoxyaethylaminoderivate und Verfahren zu ihrer Herstellung
DE1915230A1 (de) Hydroxyphenylalkylaminderivate und Verfahren zu deren Herstellung
DE2840786C2 (enExample)
DD153550A5 (de) Verfahren zur herstellung von neuer 1,2,4-oxadiazolin-5-on-derivaten
DE2802306A1 (de) Azacycloalkane, azacycloalkene und ihre derivate
DE1670622A1 (de) Verfahren zur Herstellung von Aminoalkyl-pyrrol-2-yl-ketonen
DE1643198A1 (de) Diarylcyclopropanderivate und Verfahren zu ihrer Herstellung
DE2738131A1 (de) Aminoketone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2638849C2 (de) 2-Aminopropionsäure-2-trifluormethylphenyl-1,1-dimethyläthylester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2846880A1 (de) Substituierte chinolizidin- und indolizidinmethanolderivate, verfahren zur herstellung derselben und arzneimittel, welche diese enthalten
EP0280290A2 (de) Mittel mit antidepressiver Wirkung
DE2513806A1 (de) Alkylsulfonylphenoxypropanolamine, verfahren zu ihrer herstellung und sie enthaltende mittel
DE1643237C3 (de) Kernsubstituierte 1-Nitrilophenoxy-3-tert.-butylamino-2-propanole, Verfahren zu deren Herstellung und pharmazeutische Präparate auf deren Basis
AT281036B (de) Verfahren zur Herstellung von neuen Benz-epinderivaten und ihren Säureadditionssalzen
AT344714B (de) Verfahren zur herstellung von neuen morpholinderivaten und von ihren saeureadditionssalzen

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection