DE2516674A1 - Heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel - Google Patents

Heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel

Info

Publication number
DE2516674A1
DE2516674A1 DE19752516674 DE2516674A DE2516674A1 DE 2516674 A1 DE2516674 A1 DE 2516674A1 DE 19752516674 DE19752516674 DE 19752516674 DE 2516674 A DE2516674 A DE 2516674A DE 2516674 A1 DE2516674 A1 DE 2516674A1
Authority
DE
Germany
Prior art keywords
pyridyl
compound
carbonyl
triazole
bromo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752516674
Other languages
German (de)
English (en)
Inventor
Yutaka Kuwada
Kanji Meguro
Hideaki Natsugari
Hiroyuki Tawada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE2516674A1 publication Critical patent/DE2516674A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19752516674 1974-04-17 1975-04-16 Heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel Withdrawn DE2516674A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49043725A JPS5747915B2 (fr) 1974-04-17 1974-04-17

Publications (1)

Publication Number Publication Date
DE2516674A1 true DE2516674A1 (de) 1975-10-30

Family

ID=12671752

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752516674 Withdrawn DE2516674A1 (de) 1974-04-17 1975-04-16 Heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel

Country Status (4)

Country Link
JP (1) JPS5747915B2 (fr)
DE (1) DE2516674A1 (fr)
FR (1) FR2267786B1 (fr)
GB (1) GB1497827A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3160969B1 (fr) 2014-06-26 2023-09-13 The Johns Hopkins University Modulateurs allostériques positifs au gaba restreints au système nerveux périphérique pour le traitement du syndrome du côlon irritable et autres affections du système nerveux périphérique

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055889A1 (de) * 1969-11-15 1971-05-27 Takeda Chemical Industries, Ltd , Osaka (Japan) Neue Benzodiazepindenvate und Ver fahren zu ihrer Herstellung
DE2159527A1 (de) * 1970-12-11 1972-06-22 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur Herstellung von Diazepinderivaten und nach diesen Verfahren herstellbare neue Diazepinderivate
DE2215943A1 (de) * 1971-04-08 1972-10-12 Ciba-Geigy Ag, Basel (Schweiz) Neue 6-Phenyl-4H-s-triazolo eckige Klammer auf 1,5-a eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu benzodiazepin-2-carbonsäuren und ihre Ester, sowie Verfahren zu deren Herstellung
DE2234620A1 (de) * 1971-07-23 1973-02-01 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung
DE2234652A1 (de) * 1971-07-23 1973-02-01 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung
DE2304307A1 (de) * 1972-02-07 1973-08-23 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055889A1 (de) * 1969-11-15 1971-05-27 Takeda Chemical Industries, Ltd , Osaka (Japan) Neue Benzodiazepindenvate und Ver fahren zu ihrer Herstellung
DE2159527A1 (de) * 1970-12-11 1972-06-22 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur Herstellung von Diazepinderivaten und nach diesen Verfahren herstellbare neue Diazepinderivate
DE2215943A1 (de) * 1971-04-08 1972-10-12 Ciba-Geigy Ag, Basel (Schweiz) Neue 6-Phenyl-4H-s-triazolo eckige Klammer auf 1,5-a eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu benzodiazepin-2-carbonsäuren und ihre Ester, sowie Verfahren zu deren Herstellung
DE2234620A1 (de) * 1971-07-23 1973-02-01 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung
DE2234652A1 (de) * 1971-07-23 1973-02-01 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung
DE2304307A1 (de) * 1972-02-07 1973-08-23 Ciba Geigy Ag Neue diazepinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS5747915B2 (fr) 1982-10-13
JPS50140492A (fr) 1975-11-11
FR2267786B1 (fr) 1978-07-28
FR2267786A1 (fr) 1975-11-14
GB1497827A (en) 1978-01-12

Similar Documents

Publication Publication Date Title
DE602004008938T3 (de) Phosphorsäuresalz eines dipeptidylpeptidase-iv-inhibitors
DE3212304A1 (de) Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3004750A1 (de) Neue heterotricyclische derivate, verfahren zu deren herstellung, ihre verwendung als arzneimittel und sie enthaltenden pharmazeutischen zusammensetzungen
DE3029281A1 (de) Substituierte tetraazatricyclen, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende arzneimittel
DE2617205A1 (de) Anorektische verbindungen
DE2726389A1 (de) Pyrazolo eckige klammer auf 1,5-c eckige klammer zu chinazoline, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE2215943A1 (de) Neue 6-Phenyl-4H-s-triazolo eckige Klammer auf 1,5-a eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu benzodiazepin-2-carbonsäuren und ihre Ester, sowie Verfahren zu deren Herstellung
DE602005002751T2 (de) Substituierte tricyclische benzimidazole
DE2516674A1 (de) Heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
EP0180115A2 (fr) 1,2,4-Triazolyl carbamates et leurs sels d'addition acides, procédé pour leur préparation et médicaments
DE1955349C2 (de) s-Triazolo [4,3-a] [1,4] benzodiazepine
US3679662A (en) Tetrahydrocyclopropadibenzazepine derivatives
DE2809591A1 (de) Benzodiazepin-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel
DE2520143A1 (de) Neue heterocyclische verbindungen, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2609862C2 (fr)
DE2521326A1 (de) Neue thienodiazepinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2508329A1 (de) Neue heterocyclische verbindungen, deren herstellung und diese enthaltende pharmazeutische mittel
DD261788A5 (de) Verfahren zur herstellung von tetradydroimidazochinazolinon-herzstimulantien
DE2514663A1 (de) Neue thienodiazepinderivate, verfahren zur herstellung derselben und diese enthaltende arzneimittel
DE2541464A1 (de) 1,2,4-triazolderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2515209A1 (de) Benzodiazepinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE60006026T2 (de) Verfahren zur Herstellung von 8-cyclopentyl-6-ethyl-3 (substituierten)-5,8-dihydro-4H-1,2,3A,7,8-penta aza-as-Indacenen und dafür geeigneter Zwischenprodukte
DE2410030C3 (de) 8-Brom-6-phenyl-4H-s-triazolo[3,4-c]thieno[2,3-e]1,4-diazepine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CH655115A5 (de) Substituierte aethenylderivate von 1h-pyrazolo-(1,5-a)-pyrimidin und verfahren zur herstellung derselben.
DE2460776C2 (de) 1-substituierte 6-Aryl-4H-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate sowie Zwischenprodukte und Verfahren zur Herstellung dieser Zwischenprodukte

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee