DE2418805C3 - 16β -Carboxy-11,17α -dimethoxy-18β -benzoyloxy-yohimbanderivate und Verfahren zu deren Herstellung - Google Patents

16β -Carboxy-11,17α -dimethoxy-18β -benzoyloxy-yohimbanderivate und Verfahren zu deren Herstellung

Info

Publication number
DE2418805C3
DE2418805C3 DE2418805A DE2418805A DE2418805C3 DE 2418805 C3 DE2418805 C3 DE 2418805C3 DE 2418805 A DE2418805 A DE 2418805A DE 2418805 A DE2418805 A DE 2418805A DE 2418805 C3 DE2418805 C3 DE 2418805C3
Authority
DE
Germany
Prior art keywords
dimethoxy
melting point
acid
benzoyloxy
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2418805A
Other languages
German (de)
English (en)
Other versions
DE2418805A1 (de
DE2418805B2 (OSRAM
Inventor
Luigi Fontanella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of DE2418805A1 publication Critical patent/DE2418805A1/de
Publication of DE2418805B2 publication Critical patent/DE2418805B2/de
Application granted granted Critical
Publication of DE2418805C3 publication Critical patent/DE2418805C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D459/00—Heterocyclic compounds containing benz [g] indolo [2, 3-a] quinolizine ring systems, e.g. yohimbine; 16, 18-lactones thereof, e.g. reserpic acid lactone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE2418805A 1973-05-25 1974-04-19 16β -Carboxy-11,17α -dimethoxy-18β -benzoyloxy-yohimbanderivate und Verfahren zu deren Herstellung Expired DE2418805C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2515873A GB1418831A (en) 1973-05-25 1973-05-25 Reserpine derivatives

Publications (3)

Publication Number Publication Date
DE2418805A1 DE2418805A1 (de) 1974-12-19
DE2418805B2 DE2418805B2 (OSRAM) 1980-07-03
DE2418805C3 true DE2418805C3 (de) 1981-06-04

Family

ID=10223164

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2418805A Expired DE2418805C3 (de) 1973-05-25 1974-04-19 16β -Carboxy-11,17α -dimethoxy-18β -benzoyloxy-yohimbanderivate und Verfahren zu deren Herstellung

Country Status (13)

Country Link
US (1) US3978065A (OSRAM)
JP (1) JPS5540590B2 (OSRAM)
AR (1) AR209913A1 (OSRAM)
BE (1) BE815492A (OSRAM)
CA (1) CA1039728A (OSRAM)
CH (1) CH592089A5 (OSRAM)
DE (1) DE2418805C3 (OSRAM)
DK (1) DK139430B (OSRAM)
ES (1) ES426662A1 (OSRAM)
FR (1) FR2230362B1 (OSRAM)
GB (1) GB1418831A (OSRAM)
NL (1) NL161757C (OSRAM)
SE (1) SE417967B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6276554U (OSRAM) * 1985-11-01 1987-05-16
DE102011108116A1 (de) * 2011-07-21 2013-01-24 Dr. Loges + Co. Gmbh Reserpin zur Behandlung von kognitiven Störungen des zentralen Nervensystems
CN103467281B (zh) * 2013-07-25 2016-03-23 武汉英纳氏药业有限公司 一种苯酚衍生物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2926167A (en) * 1960-02-23 Process of esterifying ib-hydroxy
US3126390A (en) * 1964-03-24 Ib-epi-deserpidates and derivatives
US2819271A (en) * 1956-06-22 1958-01-07 Upjohn Co Methyl reserpate o-triacetylshikimate
US2952682A (en) * 1956-10-31 1960-09-13 Lab Francais Chimiotherapie Polycyclic compounds and process of preparing same
US2933499A (en) * 1958-03-03 1960-04-19 Upjohn Co Lower alkyl reserpate omicron-
US3109003A (en) * 1962-10-24 1963-10-29 Upjohn Co Lower alkyl reserpate-18-[alpha-methyl-beta-(3, 4, 5-trimethoxyphenyl)]-acrylate

Also Published As

Publication number Publication date
DK282974A (OSRAM) 1975-01-20
SE417967B (sv) 1981-04-27
CA1039728A (en) 1978-10-03
AR209913A1 (es) 1977-06-15
CH592089A5 (OSRAM) 1977-10-14
FR2230362A1 (OSRAM) 1974-12-20
ES426662A1 (es) 1976-07-16
FR2230362B1 (OSRAM) 1978-06-30
JPS5540590B2 (OSRAM) 1980-10-18
DK139430C (OSRAM) 1979-07-30
NL7406163A (OSRAM) 1974-11-27
DE2418805A1 (de) 1974-12-19
DK139430B (da) 1979-02-19
NL161757B (nl) 1979-10-15
NL161757C (nl) 1980-03-17
BE815492A (fr) 1974-09-16
US3978065A (en) 1976-08-31
DE2418805B2 (OSRAM) 1980-07-03
JPS5040600A (OSRAM) 1975-04-14
GB1418831A (en) 1975-12-24

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee