BE815492A - Nouveaux derives de la reserpine - Google Patents
Nouveaux derives de la reserpineInfo
- Publication number
- BE815492A BE815492A BE144709A BE144709A BE815492A BE 815492 A BE815492 A BE 815492A BE 144709 A BE144709 A BE 144709A BE 144709 A BE144709 A BE 144709A BE 815492 A BE815492 A BE 815492A
- Authority
- BE
- Belgium
- Prior art keywords
- reserpine
- new derivatives
- derivatives
- new
- Prior art date
Links
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 title 1
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 title 1
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 title 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 title 1
- 229960003147 reserpine Drugs 0.000 title 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D459/00—Heterocyclic compounds containing benz [g] indolo [2, 3-a] quinolizine ring systems, e.g. yohimbine; 16, 18-lactones thereof, e.g. reserpic acid lactone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2515873A GB1418831A (en) | 1973-05-25 | 1973-05-25 | Reserpine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE815492A true BE815492A (fr) | 1974-09-16 |
Family
ID=10223164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE144709A BE815492A (fr) | 1973-05-25 | 1974-05-24 | Nouveaux derives de la reserpine |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3978065A (fr) |
| JP (1) | JPS5540590B2 (fr) |
| AR (1) | AR209913A1 (fr) |
| BE (1) | BE815492A (fr) |
| CA (1) | CA1039728A (fr) |
| CH (1) | CH592089A5 (fr) |
| DE (1) | DE2418805C3 (fr) |
| DK (1) | DK139430B (fr) |
| ES (1) | ES426662A1 (fr) |
| FR (1) | FR2230362B1 (fr) |
| GB (1) | GB1418831A (fr) |
| NL (1) | NL161757C (fr) |
| SE (1) | SE417967B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6276554U (fr) * | 1985-11-01 | 1987-05-16 | ||
| DE102011108116A1 (de) * | 2011-07-21 | 2013-01-24 | Dr. Loges + Co. Gmbh | Reserpin zur Behandlung von kognitiven Störungen des zentralen Nervensystems |
| CN103467281B (zh) * | 2013-07-25 | 2016-03-23 | 武汉英纳氏药业有限公司 | 一种苯酚衍生物及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3126390A (en) * | 1964-03-24 | Ib-epi-deserpidates and derivatives | ||
| US2926167A (en) * | 1960-02-23 | Process of esterifying ib-hydroxy | ||
| US2819271A (en) * | 1956-06-22 | 1958-01-07 | Upjohn Co | Methyl reserpate o-triacetylshikimate |
| US2952682A (en) * | 1956-10-31 | 1960-09-13 | Lab Francais Chimiotherapie | Polycyclic compounds and process of preparing same |
| US2933499A (en) * | 1958-03-03 | 1960-04-19 | Upjohn Co | Lower alkyl reserpate omicron- |
| US3109003A (en) * | 1962-10-24 | 1963-10-29 | Upjohn Co | Lower alkyl reserpate-18-[alpha-methyl-beta-(3, 4, 5-trimethoxyphenyl)]-acrylate |
-
1973
- 1973-05-25 GB GB2515873A patent/GB1418831A/en not_active Expired
-
1974
- 1974-04-19 DE DE2418805A patent/DE2418805C3/de not_active Expired
- 1974-05-08 NL NL7406163.A patent/NL161757C/xx not_active IP Right Cessation
- 1974-05-21 FR FR7417694A patent/FR2230362B1/fr not_active Expired
- 1974-05-23 AR AR253889A patent/AR209913A1/es active
- 1974-05-24 JP JP5864874A patent/JPS5540590B2/ja not_active Expired
- 1974-05-24 SE SE7406935A patent/SE417967B/xx unknown
- 1974-05-24 BE BE144709A patent/BE815492A/fr unknown
- 1974-05-24 US US05/473,024 patent/US3978065A/en not_active Expired - Lifetime
- 1974-05-24 CH CH713174A patent/CH592089A5/xx not_active IP Right Cessation
- 1974-05-24 CA CA200,730A patent/CA1039728A/fr not_active Expired
- 1974-05-24 DK DK282974AA patent/DK139430B/da not_active IP Right Cessation
- 1974-05-25 ES ES426662A patent/ES426662A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1418831A (en) | 1975-12-24 |
| NL7406163A (fr) | 1974-11-27 |
| CA1039728A (fr) | 1978-10-03 |
| DE2418805A1 (de) | 1974-12-19 |
| JPS5540590B2 (fr) | 1980-10-18 |
| DE2418805C3 (de) | 1981-06-04 |
| DE2418805B2 (fr) | 1980-07-03 |
| NL161757C (nl) | 1980-03-17 |
| FR2230362B1 (fr) | 1978-06-30 |
| DK139430C (fr) | 1979-07-30 |
| US3978065A (en) | 1976-08-31 |
| CH592089A5 (fr) | 1977-10-14 |
| AR209913A1 (es) | 1977-06-15 |
| DK282974A (fr) | 1975-01-20 |
| JPS5040600A (fr) | 1975-04-14 |
| NL161757B (nl) | 1979-10-15 |
| DK139430B (da) | 1979-02-19 |
| FR2230362A1 (fr) | 1974-12-20 |
| SE417967B (sv) | 1981-04-27 |
| ES426662A1 (es) | 1976-07-16 |
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