DE2337340C2 - 6-Chlor-α-methylcarbazol-2-essigsäure und deren Salze - Google Patents
6-Chlor-α-methylcarbazol-2-essigsäure und deren SalzeInfo
- Publication number
- DE2337340C2 DE2337340C2 DE2337340A DE2337340A DE2337340C2 DE 2337340 C2 DE2337340 C2 DE 2337340C2 DE 2337340 A DE2337340 A DE 2337340A DE 2337340 A DE2337340 A DE 2337340A DE 2337340 C2 DE2337340 C2 DE 2337340C2
- Authority
- DE
- Germany
- Prior art keywords
- acetic acid
- chloro
- methyl
- solution
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27414272A | 1972-07-24 | 1972-07-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2337340A1 DE2337340A1 (de) | 1974-02-14 |
| DE2337340C2 true DE2337340C2 (de) | 1985-05-02 |
Family
ID=23046965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2337340A Expired DE2337340C2 (de) | 1972-07-24 | 1973-07-23 | 6-Chlor-α-methylcarbazol-2-essigsäure und deren Salze |
Country Status (26)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146542A (en) * | 1978-06-12 | 1979-03-27 | Hoffmann-La Roche Inc. | Dihydrocarbazole acetic acid and esters thereof |
| US4150031A (en) * | 1978-06-26 | 1979-04-17 | Hoffmann-La Roche Inc. | Hydroxy methyl carbazole acetic acid and esters |
| US4158007A (en) * | 1978-08-21 | 1979-06-12 | Hoffmann-La Roche Inc. | Carbazole methyl malonates |
| US4501908A (en) * | 1981-03-12 | 1985-02-26 | Hoffmann-La Roche Inc. | 2,3-Isopropylidene ribonic acid, 1,4-lactones |
| JPS6040256U (ja) * | 1983-08-25 | 1985-03-20 | 伊東 璋 | 容器類洗浄機 |
| EP0234708B1 (en) * | 1986-01-23 | 1991-02-27 | Merck Frosst Canada Inc. | Tetrahydrocarbazole 1-alkanoic acids |
| EP0239306B1 (en) | 1986-03-27 | 1993-06-02 | Merck Frosst Canada Inc. | Tetrahydrocarbazole esters |
| EP0307077A1 (en) * | 1987-07-21 | 1989-03-15 | Merck Frosst Canada Inc. | Tetrahydrocarbazoles for the improvement of cyclosporin therapy |
| CA1326030C (en) * | 1987-07-21 | 1994-01-11 | John W. Gillard | Cyclohept[b]indolealkanoic acids |
| PT95692A (pt) * | 1989-10-27 | 1991-09-13 | American Home Prod | Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase |
| US6013808A (en) * | 1998-06-16 | 2000-01-11 | Pfizer Inc. | Method of purifying carbazole ester precursors of 6-chloro-α-methyl-carbazole-2-acetic acid |
| JP2004010601A (ja) * | 2002-06-11 | 2004-01-15 | Nippon Steel Chem Co Ltd | インドール誘導体の製造方法及びそのための有用な中間体 |
| CA2512704A1 (en) | 2003-01-14 | 2004-08-05 | Merck & Co., Inc. | Geminally di-substituted nsaid derivatives as abeta 42 lowering agents |
| MXPA05011850A (es) * | 2003-05-06 | 2006-05-25 | Air Prod & Chem | Almacen de hidrogeno reversible hidrogenado de los sustratros pi-conjugados. |
| CA2535497A1 (en) * | 2003-08-15 | 2005-02-24 | Universite Laval | Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles |
| US7601856B2 (en) | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
| US7662831B2 (en) | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| ES2729713T3 (es) * | 2011-11-15 | 2019-11-05 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Compuestos tricíclicos, composiciones que los comprenden y usos de los mismos |
| JP5940036B2 (ja) * | 2013-10-08 | 2016-06-29 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ |
| CN114787130A (zh) * | 2020-03-25 | 2022-07-22 | 捷恩智株式会社 | 化合物、液晶组合物及液晶显示元件 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD70880A (cg-RX-API-DMAC10.html) * | ||||
| US3580926A (en) * | 1969-11-10 | 1971-05-25 | Parke Davis & Co | Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids |
| ZA715217B (en) * | 1970-08-20 | 1972-04-26 | Org Nv | Anti-inflammatory preparations |
-
1973
- 1973-01-01 AR AR249230A patent/AR205331A1/es active
- 1973-06-14 ZA ZA734047A patent/ZA734047B/xx unknown
- 1973-06-15 CH CH871673A patent/CH587819A5/xx not_active IP Right Cessation
- 1973-07-20 HU HUHO1597A patent/HU167611B/hu unknown
- 1973-07-20 BE BE133691A patent/BE802596A/xx not_active IP Right Cessation
- 1973-07-20 IL IL42799A patent/IL42799A/en unknown
- 1973-07-20 KR KR7301174A patent/KR780000289B1/ko not_active Expired
- 1973-07-23 LU LU68071A patent/LU68071A1/xx unknown
- 1973-07-23 IE IE1252/73A patent/IE37942B1/xx unknown
- 1973-07-23 DD DD172456A patent/DD107681A5/xx unknown
- 1973-07-23 JP JP48081008A patent/JPS5740144B2/ja not_active Expired
- 1973-07-23 CA CA177,061A patent/CA1026348A/en not_active Expired
- 1973-07-23 GB GB3496873A patent/GB1385620A/en not_active Expired
- 1973-07-23 DK DK405973AA patent/DK138537B/da not_active IP Right Cessation
- 1973-07-23 AT AT649773A patent/AT325607B/de not_active IP Right Cessation
- 1973-07-23 SE SE7310244A patent/SE402283B/xx unknown
- 1973-07-23 DE DE2337340A patent/DE2337340C2/de not_active Expired
- 1973-07-23 AU AU58390/73A patent/AU475534B2/en not_active Expired
- 1973-07-23 FI FI2311/73A patent/FI59244C/fi active
- 1973-07-23 NO NO2975/73A patent/NO142865C/no unknown
- 1973-07-24 FR FR7327020A patent/FR2193611B1/fr not_active Expired
- 1973-07-24 SU SU1950151A patent/SU509220A3/ru active
- 1973-07-24 NL NLAANVRAGE7310275,A patent/NL169877C/xx not_active IP Right Cessation
-
1976
- 1976-05-21 SE SE7605813A patent/SE7605813L/xx unknown
-
1978
- 1978-06-13 KE KE2847A patent/KE2847A/xx unknown
- 1978-08-31 HK HK498/78A patent/HK49878A/xx unknown
- 1978-12-30 MY MY315/78A patent/MY7800315A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH |
|
| 8328 | Change in the person/name/address of the agent |
Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT |