DE2157040A1 - Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen - Google Patents

Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen

Info

Publication number
DE2157040A1
DE2157040A1 DE2157040A DE2157040A DE2157040A1 DE 2157040 A1 DE2157040 A1 DE 2157040A1 DE 2157040 A DE2157040 A DE 2157040A DE 2157040 A DE2157040 A DE 2157040A DE 2157040 A1 DE2157040 A1 DE 2157040A1
Authority
DE
Germany
Prior art keywords
amino
formula
solvent
oxazolidones
oxazolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2157040A
Other languages
German (de)
English (en)
Inventor
Johannes Dr Dipl Chem Keck
Axel Dipl Chem Dr Prox
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to DE2157040A priority Critical patent/DE2157040A1/de
Priority to JP10453671A priority patent/JPS5512893B2/ja
Priority to AT943572A priority patent/AT320618B/de
Priority to AT1038373A priority patent/AT320642B/de
Priority to SU1847357A priority patent/SU468398A3/ru
Priority to CH1654972A priority patent/CH574903A5/xx
Priority to YU2815/72A priority patent/YU35870B/xx
Priority to HUTO893A priority patent/HU164697B/hu
Priority to RO7272820A priority patent/RO68219A/ro
Priority to ES408615A priority patent/ES408615A1/es
Priority to DD174171*A priority patent/DD108297A5/xx
Priority to HUTO936A priority patent/HU166034B/hu
Priority to BG021865A priority patent/BG20337A3/xx
Priority to CS7736A priority patent/CS170454B2/cs
Priority to DD166875A priority patent/DD103640A5/xx
Priority to CA156,600A priority patent/CA987685A/en
Priority to PL1972158883A priority patent/PL79757B1/pl
Publication of DE2157040A1 publication Critical patent/DE2157040A1/de
Priority to DK086574AA priority patent/DK150851B/da
Priority to SE7505550A priority patent/SE405854B/xx
Priority to JP12337176A priority patent/JPS5293767A/ja
Priority to FI792528A priority patent/FI792528A7/fi
Priority to YU2525/79A priority patent/YU40763B/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE2157040A 1971-11-17 1971-11-17 Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen Pending DE2157040A1 (de)

Priority Applications (22)

Application Number Priority Date Filing Date Title
DE2157040A DE2157040A1 (de) 1971-11-17 1971-11-17 Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen
JP10453671A JPS5512893B2 (enrdf_load_stackoverflow) 1971-11-17 1971-12-22
AT943572A AT320618B (de) 1971-11-17 1972-11-07 Verfahren zur Herstellung von 4-Amino-3,5-dihalogenphenyl-äthanolaminen sowie deren Säureadditionssalzen
AT1038373A AT320642B (de) 1971-11-17 1972-11-07 Verfahren zur Herstellung von neuen Oxazolidonen
SU1847357A SU468398A3 (ru) 1971-11-17 1972-11-14 Способ получени 4-амино-3,5дигалогенфенилэтаноламинов
CH1654972A CH574903A5 (enrdf_load_stackoverflow) 1971-11-17 1972-11-14
YU2815/72A YU35870B (en) 1971-11-17 1972-11-14 Process for preparing 4-amino-3,5-dihalo-phenyl-ethanolamines
HUTO936A HU166034B (enrdf_load_stackoverflow) 1971-11-17 1972-11-15
RO7272820A RO68219A (ro) 1971-11-17 1972-11-15 Procedeu pentru prepararea de 4-amino-3,5-dihalogen-fenil-etanolamine
ES408615A ES408615A1 (es) 1971-11-17 1972-11-15 Procedimiento para la preparacion de 4-amino-3,5-dihalogenofenil - etanolaminas.
DD174171*A DD108297A5 (enrdf_load_stackoverflow) 1971-11-17 1972-11-15
HUTO893A HU164697B (enrdf_load_stackoverflow) 1971-11-17 1972-11-15
BG021865A BG20337A3 (bg) 1971-11-17 1972-11-15 Метод за получаване на 4-амино-3,5-дихалогенен-фенил-етаноламини
CS7736A CS170454B2 (enrdf_load_stackoverflow) 1971-11-17 1972-11-15
DD166875A DD103640A5 (enrdf_load_stackoverflow) 1971-11-17 1972-11-15
PL1972158883A PL79757B1 (enrdf_load_stackoverflow) 1971-11-17 1972-11-16
CA156,600A CA987685A (en) 1971-11-17 1972-11-16 Process for the preparation of 4-amino-3,5-dihalogen-phenyl-ethanolamines
DK086574AA DK150851B (da) 1971-11-17 1974-02-18 Oxazolidon-(2)-forbindelser til anvendelse som mellemprodukter til fremstilling af 4-amino-3,5-dihalogen-phenylethanolaminer
SE7505550A SE405854B (sv) 1971-11-17 1975-05-14 Nya oxazolidoner
JP12337176A JPS5293767A (en) 1971-11-17 1976-10-14 Novel oxazolidone derivatives and preparation thereof
FI792528A FI792528A7 (fi) 1971-11-17 1979-08-15 Uudet välituotteet ja menetelmä niiden valmistamiseksi.
YU2525/79A YU40763B (en) 1971-11-17 1979-10-17 Process for preparing new oxazolidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2157040A DE2157040A1 (de) 1971-11-17 1971-11-17 Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen

Publications (1)

Publication Number Publication Date
DE2157040A1 true DE2157040A1 (de) 1973-05-24

Family

ID=5825380

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2157040A Pending DE2157040A1 (de) 1971-11-17 1971-11-17 Neues verfahren zur herstellung von 4-amino-3,5-dihalogen-phenyl-aethanolaminen

Country Status (17)

Country Link
JP (2) JPS5512893B2 (enrdf_load_stackoverflow)
AT (2) AT320618B (enrdf_load_stackoverflow)
BG (1) BG20337A3 (enrdf_load_stackoverflow)
CA (1) CA987685A (enrdf_load_stackoverflow)
CH (1) CH574903A5 (enrdf_load_stackoverflow)
CS (1) CS170454B2 (enrdf_load_stackoverflow)
DD (2) DD103640A5 (enrdf_load_stackoverflow)
DE (1) DE2157040A1 (enrdf_load_stackoverflow)
DK (1) DK150851B (enrdf_load_stackoverflow)
ES (1) ES408615A1 (enrdf_load_stackoverflow)
FI (1) FI792528A7 (enrdf_load_stackoverflow)
HU (2) HU166034B (enrdf_load_stackoverflow)
PL (1) PL79757B1 (enrdf_load_stackoverflow)
RO (1) RO68219A (enrdf_load_stackoverflow)
SE (1) SE405854B (enrdf_load_stackoverflow)
SU (1) SU468398A3 (enrdf_load_stackoverflow)
YU (2) YU35870B (enrdf_load_stackoverflow)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2354961A1 (de) * 1973-11-02 1975-06-05 Thomae Gmbh Dr K Neue verfahren zur herstellung von amino-phenyl-aethanolaminen
US5059422A (en) * 1985-07-29 1991-10-22 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US5169633A (en) * 1985-07-29 1992-12-08 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US10288602B2 (en) 2013-01-08 2019-05-14 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatement
US11357757B2 (en) 2017-09-13 2022-06-14 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia
US11427539B2 (en) 2017-09-13 2022-08-30 Atrogi Ab Beta-hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia
US11648216B2 (en) 2017-09-13 2023-05-16 Atrogi Ab Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia
US11793774B2 (en) 2017-09-13 2023-10-24 Atrogi Ab Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia
WO2023203223A1 (en) 2022-04-22 2023-10-26 Atrogi Ab Combinations of beta 2-adrenergic receptor agonists and beta 3-adrenergic receptor agonists, and medical uses thereof
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
WO2024170727A1 (en) 2023-02-16 2024-08-22 Atrogi Ab Combinations of beta 2-adrenergic receptor agonists and metformin for use in treating obesity and reducing body fat
WO2024184408A1 (en) 2023-03-06 2024-09-12 Atrogi Ab Combination of beta-2-adrenergic receptor agonists and glp-1 receptor agonists for use in treating hyperglycaemia
US12378216B2 (en) 2019-03-20 2025-08-05 Atrogi Ab Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618005A1 (de) * 1966-09-22 1971-09-09 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2354961A1 (de) * 1973-11-02 1975-06-05 Thomae Gmbh Dr K Neue verfahren zur herstellung von amino-phenyl-aethanolaminen
US5059422A (en) * 1985-07-29 1991-10-22 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US5169633A (en) * 1985-07-29 1992-12-08 American Cyanamid Company Continuous release phenylethanolamine derivative compositions
US10288602B2 (en) 2013-01-08 2019-05-14 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatement
US11648216B2 (en) 2017-09-13 2023-05-16 Atrogi Ab Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia
US11427539B2 (en) 2017-09-13 2022-08-30 Atrogi Ab Beta-hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia
US11357757B2 (en) 2017-09-13 2022-06-14 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia
US11793774B2 (en) 2017-09-13 2023-10-24 Atrogi Ab Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia
US12036210B2 (en) 2017-09-13 2024-07-16 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia
US12280023B2 (en) 2017-09-13 2025-04-22 Atrogi Ab Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia
US12378216B2 (en) 2019-03-20 2025-08-05 Atrogi Ab Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia
WO2023203223A1 (en) 2022-04-22 2023-10-26 Atrogi Ab Combinations of beta 2-adrenergic receptor agonists and beta 3-adrenergic receptor agonists, and medical uses thereof
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
WO2024170727A1 (en) 2023-02-16 2024-08-22 Atrogi Ab Combinations of beta 2-adrenergic receptor agonists and metformin for use in treating obesity and reducing body fat
WO2024184408A1 (en) 2023-03-06 2024-09-12 Atrogi Ab Combination of beta-2-adrenergic receptor agonists and glp-1 receptor agonists for use in treating hyperglycaemia

Also Published As

Publication number Publication date
SE405854B (sv) 1979-01-08
CH574903A5 (enrdf_load_stackoverflow) 1976-04-30
YU35870B (en) 1981-08-31
AT320642B (de) 1975-02-25
HU164697B (enrdf_load_stackoverflow) 1974-03-28
BG20337A3 (bg) 1975-11-05
PL79757B1 (enrdf_load_stackoverflow) 1975-06-30
HU166034B (enrdf_load_stackoverflow) 1974-12-28
DD108297A5 (enrdf_load_stackoverflow) 1974-09-12
JPS4857941A (enrdf_load_stackoverflow) 1973-08-14
JPS5422977B2 (enrdf_load_stackoverflow) 1979-08-10
CA987685A (en) 1976-04-20
ES408615A1 (es) 1975-10-01
JPS5512893B2 (enrdf_load_stackoverflow) 1980-04-04
DD103640A5 (enrdf_load_stackoverflow) 1974-02-05
DK150851B (da) 1987-07-06
AT320618B (de) 1975-02-25
JPS5293767A (en) 1977-08-06
SU468398A3 (ru) 1975-04-25
SE7505550L (enrdf_load_stackoverflow) 1975-05-14
FI792528A7 (fi) 1981-01-01
YU40763B (en) 1986-06-30
RO68219A (ro) 1980-03-15
YU281572A (en) 1981-02-28
YU252579A (en) 1983-01-21
CS170454B2 (enrdf_load_stackoverflow) 1976-08-27

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