DE2134439A1 - Antibakterielle Mittel und Verfahren zu deren Herstellung - Google Patents

Antibakterielle Mittel und Verfahren zu deren Herstellung

Info

Publication number
DE2134439A1
DE2134439A1 DE19712134439 DE2134439A DE2134439A1 DE 2134439 A1 DE2134439 A1 DE 2134439A1 DE 19712134439 DE19712134439 DE 19712134439 DE 2134439 A DE2134439 A DE 2134439A DE 2134439 A1 DE2134439 A1 DE 2134439A1
Authority
DE
Germany
Prior art keywords
formula
cooh
compound
salt
toxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19712134439
Other languages
German (de)
English (en)
Inventor
William Joesph; Cheney Lee Cannon;Fayetterville N.Y. Gottstein (V.St.A.). M
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE2134439A1 publication Critical patent/DE2134439A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19712134439 1970-10-05 1971-07-09 Antibakterielle Mittel und Verfahren zu deren Herstellung Ceased DE2134439A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7816570A 1970-10-05 1970-10-05

Publications (1)

Publication Number Publication Date
DE2134439A1 true DE2134439A1 (de) 1972-05-25

Family

ID=22142337

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712134439 Ceased DE2134439A1 (de) 1970-10-05 1971-07-09 Antibakterielle Mittel und Verfahren zu deren Herstellung

Country Status (13)

Country Link
US (1) US3714146A (enExample)
BG (3) BG20607A3 (enExample)
CS (1) CS176171B2 (enExample)
DE (1) DE2134439A1 (enExample)
ES (2) ES394335A1 (enExample)
FI (1) FI58133C (enExample)
GB (1) GB1314758A (enExample)
IL (1) IL37195A (enExample)
NO (2) NO145954C (enExample)
PL (2) PL85296B1 (enExample)
RO (2) RO61185A (enExample)
SE (1) SE383889B (enExample)
SU (2) SU574158A3 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50129587A (enExample) * 1974-03-28 1975-10-13

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846417A (en) * 1972-06-23 1974-11-05 Squibb & Sons Inc 1,4-cyclohexadienyl imidazolidinyl cephalosporanic acids and derivatives thereof
US4125716A (en) * 1977-12-16 1978-11-14 Bristol-Myers Company Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids
US5229509A (en) * 1989-01-10 1993-07-20 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670625A1 (de) * 1966-09-14 1970-08-06 Lilly Co Eli 7-alpha-Aminobenzyl-3-methylcephalosporinanaloge und ihre Herstellung
DE2006689A1 (de) * 1969-02-14 1970-08-27 Eli Lilly and Company, Indianapolis, Ind. (V.St.A.) Umwandlung von Penicillinsulfoxidestern in Desacetylkephalosporinester
BE747120A (fr) * 1969-12-05 1970-09-10 Glaxo Lab Ltd Procede pour obtenir des composes de cephalosporine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3464985A (en) * 1967-08-18 1969-09-02 Bristol Myers Co 7 - (d - alpha - amino - (acetamidophenylacetamido))-cephalosporanic acids and derivatives thereof
CY773A (en) * 1967-09-05 1975-03-01 Bristol Myers Co Antibacterial agents and a process for the preparation thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670625A1 (de) * 1966-09-14 1970-08-06 Lilly Co Eli 7-alpha-Aminobenzyl-3-methylcephalosporinanaloge und ihre Herstellung
DE2006689A1 (de) * 1969-02-14 1970-08-27 Eli Lilly and Company, Indianapolis, Ind. (V.St.A.) Umwandlung von Penicillinsulfoxidestern in Desacetylkephalosporinester
BE747120A (fr) * 1969-12-05 1970-09-10 Glaxo Lab Ltd Procede pour obtenir des composes de cephalosporine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
In Betracht gezogene ältere Patente: DE-PS 21 17 377 *
J. Org. Chem. 37, 1972, 2766 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50129587A (enExample) * 1974-03-28 1975-10-13

Also Published As

Publication number Publication date
NO145953C (no) 1982-06-30
SU574158A3 (ru) 1977-09-25
GB1314758A (en) 1973-04-26
NO145953B (no) 1982-03-22
PL85296B1 (en) 1976-04-30
ES394335A1 (es) 1974-11-01
NO145954B (no) 1982-03-22
SE383889B (sv) 1976-04-05
CS176171B2 (enExample) 1977-06-30
RO60513A (enExample) 1976-08-15
PL91952B1 (en) 1977-03-31
BG21034A3 (bg) 1976-01-20
ES419757A1 (es) 1976-06-01
US3714146A (en) 1973-01-30
SU625614A3 (ru) 1978-09-25
BG20607A3 (bg) 1975-12-05
RO61185A (enExample) 1976-07-15
FI58133C (fi) 1980-12-10
NO145954C (no) 1982-06-30
IL37195A (en) 1975-02-10
IL37195A0 (en) 1971-11-29
FI58133B (fi) 1980-08-29
BG20608A3 (bg) 1975-12-05

Similar Documents

Publication Publication Date Title
CH628901A5 (de) Verfahren zur herstellung von cephalosporinantibiotika.
DE3018590A1 (de) Bisester von methandiol mit penicillinen und penicillansaeure-1,1-dioxid
DE2824535B2 (de) Penkillansäure-l.l-dioxide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE1670625C3 (de) y-alpha-Aminobenzyl-S-methylcephalosporinanaloge und ihre Herstellung
DE2555858A1 (de) 3-thiosubstituierte cephalosporinverbindungen und verfahren zu ihrer herstellung
DE2606196C2 (enExample)
DE2258221C2 (de) Verfahren zur Herstellung von Penicillinen und Cepholosporinen mit einem weiteren Substituenten in 6- bzw. 7-Stellung
DE2263861A1 (de) Verfahren zur herstellung von 7acylamido-3-cephem-4-carbonsaeure
CH634330A5 (de) Verfahren zur herstellung von ungesaettigten derivaten der 7-acylamido-3-cephem-4-carbonsaeure.
CH630333A5 (de) Verfahren zur spaltung von benzylestern von carbonsaeuren.
DE2134439A1 (de) Antibakterielle Mittel und Verfahren zu deren Herstellung
DE2534926C2 (de) Verfahren zur Herstellung von Estern der 7-Oxo- und 7β-Hydroxy-cephalosporansäure und deren 3-substituierten Derivaten
DE2223667C2 (de) Verfahren zur Herstellung von 8-Oxo-5-thia-1-azabicyclo-[4,2,0]oct-2-en- oder -3-en-Verbindungen
DE2163789A1 (de) Verfahren zur Herstellung von Cephalosporinderivaten
DE2057381A1 (de) 2-Substituierte Thiazolidinverbindungen
DE2612926A1 (de) Neue acyl-derivate der 6-(alpha- amino-phenylacetamido)-penicillansaeure
DD202163A5 (de) Verfahren und zwischenstufen zur herstellung von 1,1-dixopenicillanoyloxymethyl-6 (2-amino-2-phenylacetamido)penicillanaten
DE2117377C2 (de) 6-(D-2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)-penicillansäure-Derivate, Verfahren zu ihrer Herstellung und Verfahren zur Herstellung von 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure
DE2801849A1 (de) Amino-spiro eckige klammer auf oxa- (oder thia-)-cycloalkan-penam eckige klammer zu -carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung
CH625528A5 (en) Process for the preparation of 3-methylenecepham sulphoxides
DE2461933A1 (de) Cephalosporinanaloga
DE2021073A1 (de) alpha-Amino-2,4,6-cycloheptatrienyl-methylcephalosporine und Verfahren zu ihrer Herstellung
DE2540804A1 (de) 3-heterothio-7-ureidocephalosporine
DE2716814A1 (de) Verfahren zur herstellung von 3-hydroxymethylcephemverbindungen
DE2236422C2 (de) Cephalosporinverbindungen und Verfahren zu deren Herstellung

Legal Events

Date Code Title Description
OD Request for examination
8178 Suspension cancelled
8131 Rejection