DE2131938A1 - Adenosinderivate und Verfahren zu ihrer Herstellung - Google Patents

Adenosinderivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE2131938A1
DE2131938A1 DE19712131938 DE2131938A DE2131938A1 DE 2131938 A1 DE2131938 A1 DE 2131938A1 DE 19712131938 DE19712131938 DE 19712131938 DE 2131938 A DE2131938 A DE 2131938A DE 2131938 A1 DE2131938 A1 DE 2131938A1
Authority
DE
Germany
Prior art keywords
hydrazine
radicals
parts
weight
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712131938
Other languages
German (de)
English (en)
Inventor
Mikio Honjo
Kenzo Kikuchi
Ryuji Marumoto
Yoshio Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE2131938A1 publication Critical patent/DE2131938A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE19712131938 1970-06-30 1971-06-26 Adenosinderivate und Verfahren zu ihrer Herstellung Pending DE2131938A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5750770 1970-06-30

Publications (1)

Publication Number Publication Date
DE2131938A1 true DE2131938A1 (de) 1972-01-05

Family

ID=13057634

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712131938 Pending DE2131938A1 (de) 1970-06-30 1971-06-26 Adenosinderivate und Verfahren zu ihrer Herstellung

Country Status (8)

Country Link
US (1) US3796700A (enExample)
BE (1) BE768925A (enExample)
CA (1) CA954856A (enExample)
DE (1) DE2131938A1 (enExample)
FR (1) FR2100839B1 (enExample)
GB (1) GB1351501A (enExample)
HU (1) HU163640B (enExample)
NL (1) NL7108858A (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402752A1 (en) * 1989-06-09 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-heteroaryl-purin-6-amines, a process for their preparation and their use as medicaments
US5155098A (en) * 1989-06-09 1992-10-13 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines, and pharmaceutical compositions and methods employing them
WO1993023417A1 (en) * 1992-05-14 1993-11-25 Novo Nordisk A/S Novel adenosine derivatives
US5364862A (en) * 1990-09-25 1994-11-15 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3922261A (en) * 1972-06-21 1975-11-25 Merck Patent Gmbh Adenosine derivative
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5066655A (en) * 1987-04-24 1991-11-19 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
USD337174S (en) 1991-05-16 1993-07-06 Sterling Roy J Roll on suntain oil applicator
US5432164A (en) * 1991-10-24 1995-07-11 Novo Nordisk A/S C2,N6 -disubstituted adenosine derivatives
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
CN1313861A (zh) 1998-06-23 2001-09-19 葛兰素集团有限公司 2－(嘌呤－9－基)－四氢呋喃－3,4－二醇衍生物
US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US6752981B1 (en) 1999-09-08 2004-06-22 Metabasis Therapeutics, Inc. Prodrugs for liver specific drug delivery
AR049384A1 (es) * 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
JP2017520545A (ja) 2014-07-02 2017-07-27 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用
CA3087932A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402752A1 (en) * 1989-06-09 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-heteroaryl-purin-6-amines, a process for their preparation and their use as medicaments
US5155098A (en) * 1989-06-09 1992-10-13 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines, and pharmaceutical compositions and methods employing them
US5364862A (en) * 1990-09-25 1994-11-15 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
WO1993023417A1 (en) * 1992-05-14 1993-11-25 Novo Nordisk A/S Novel adenosine derivatives
US5430027A (en) * 1992-05-14 1995-07-04 Novo Nordisk A/S 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias

Also Published As

Publication number Publication date
CA954856A (en) 1974-09-17
GB1351501A (en) 1974-05-01
HU163640B (enExample) 1973-09-27
NL7108858A (enExample) 1972-01-03
BE768925A (fr) 1971-11-03
US3796700A (en) 1974-03-12
FR2100839B1 (enExample) 1974-09-06
FR2100839A1 (enExample) 1972-03-24

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