DE2112026C3 - 3-Phenyl-l-(2-[pyrrolidinyl-(l)]-äthylamino)-3,4dihydroisochinolin, seine Herstellung und die es enthaltenden medizinischen Zusammensetzungen - Google Patents
3-Phenyl-l-(2-[pyrrolidinyl-(l)]-äthylamino)-3,4dihydroisochinolin, seine Herstellung und die es enthaltenden medizinischen ZusammensetzungenInfo
- Publication number
- DE2112026C3 DE2112026C3 DE2112026A DE2112026A DE2112026C3 DE 2112026 C3 DE2112026 C3 DE 2112026C3 DE 2112026 A DE2112026 A DE 2112026A DE 2112026 A DE2112026 A DE 2112026A DE 2112026 C3 DE2112026 C3 DE 2112026C3
- Authority
- DE
- Germany
- Prior art keywords
- phenyl
- dihydroisoquinoline
- pyrrolidinyl
- ethylamino
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707008932A FR2081572B1 (US07714131-20100511-C00001.png) | 1970-03-12 | 1970-03-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2112026A1 DE2112026A1 (de) | 1971-09-23 |
| DE2112026B2 DE2112026B2 (de) | 1979-03-08 |
| DE2112026C3 true DE2112026C3 (de) | 1979-10-25 |
Family
ID=9052168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2112026A Expired DE2112026C3 (de) | 1970-03-12 | 1971-03-12 | 3-Phenyl-l-(2-[pyrrolidinyl-(l)]-äthylamino)-3,4dihydroisochinolin, seine Herstellung und die es enthaltenden medizinischen Zusammensetzungen |
Country Status (18)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61109470U (US07714131-20100511-C00001.png) * | 1984-12-20 | 1986-07-11 | ||
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6291425B1 (en) * | 1999-09-01 | 2001-09-18 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US6426415B1 (en) | 1997-09-03 | 2002-07-30 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity |
| US6346536B1 (en) | 1997-09-03 | 2002-02-12 | Guilford Pharmaceuticals Inc. | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same |
| US20020028813A1 (en) * | 1997-09-03 | 2002-03-07 | Paul F. Jackson | Thioalkyl compounds, methods, and compositions for inhibiting parp activity |
| WO1999011622A1 (en) * | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Amino-substituted compounds, methods, and compositions for inhibiting parp activity |
| US6197785B1 (en) | 1997-09-03 | 2001-03-06 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6395749B1 (en) | 1998-05-15 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, methods, and compositions for inhibiting PARP activity |
| US6387902B1 (en) | 1998-12-31 | 2002-05-14 | Guilford Pharmaceuticals, Inc. | Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP |
| AU2001264595A1 (en) | 2000-05-19 | 2001-12-03 | Guilford Pharmaceuticals Inc. | Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses |
| US6348475B1 (en) | 2000-06-01 | 2002-02-19 | Guilford Pharmaceuticals Inc. | Methods, compounds and compositions for treating gout |
| US6545011B2 (en) | 2000-07-13 | 2003-04-08 | Guilford Pharmaceuticals Inc. | Substituted 4,9-dihydrocyclopenta[imn]phenanthridine-5-ones, derivatives thereof and their uses |
| CA3034994A1 (en) | 2008-06-03 | 2009-12-10 | Intermune, Inc. | Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3227085A (en) * | 1963-09-05 | 1966-01-04 | James L Ramer | Shot shell |
| DE1670694B2 (de) * | 1966-05-05 | 1976-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von tetrahydroisochinolinen |
| FR1583755A (US07714131-20100511-C00001.png) * | 1968-03-06 | 1969-12-05 | ||
| FR2028672A6 (US07714131-20100511-C00001.png) * | 1968-03-06 | 1970-10-16 | Rhone Poulenc Sa | |
| GB1244501A (en) * | 1968-03-09 | 1971-09-02 | Aspro Nicholas Ltd | Heterocyclic amines |
-
1970
- 1970-03-12 FR FR707008932A patent/FR2081572B1/fr not_active Expired
-
1971
- 1971-02-12 FI FI710404A patent/FI49034C/fi active
- 1971-03-04 NL NL7102897A patent/NL7102897A/xx not_active Application Discontinuation
- 1971-03-11 ZA ZA711602A patent/ZA711602B/xx unknown
- 1971-03-11 IE IE307/71A patent/IE35209B1/xx unknown
- 1971-03-11 SE SE03148/71A patent/SE360655B/xx unknown
- 1971-03-11 US US00123375A patent/US3759924A/en not_active Expired - Lifetime
- 1971-03-11 NO NO925/71A patent/NO133400C/no unknown
- 1971-03-11 CA CA107530A patent/CA933928A/en not_active Expired
- 1971-03-11 CH CH359771A patent/CH521347A/fr not_active IP Right Cessation
- 1971-03-11 IL IL36398A patent/IL36398A/en unknown
- 1971-03-11 JP JP1285971A patent/JPS5341156B1/ja active Pending
- 1971-03-11 BE BE764133A patent/BE764133A/xx unknown
- 1971-03-11 DK DK116471AA patent/DK126000B/da unknown
- 1971-03-12 DE DE2112026A patent/DE2112026C3/de not_active Expired
- 1971-03-12 AT AT216171A patent/AT303042B/de not_active IP Right Cessation
- 1971-03-12 ES ES389180A patent/ES389180A1/es not_active Expired
- 1971-04-19 GB GB23784/71A patent/GB1285016A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL36398A (en) | 1973-10-25 |
| NO133400B (US07714131-20100511-C00001.png) | 1976-01-19 |
| IL36398A0 (en) | 1971-05-26 |
| SE360655B (US07714131-20100511-C00001.png) | 1973-10-01 |
| IE35209B1 (en) | 1975-12-10 |
| IE35209L (en) | 1971-09-12 |
| DK126000B (da) | 1973-05-28 |
| CA933928A (en) | 1973-09-18 |
| US3759924A (en) | 1973-09-18 |
| BE764133A (fr) | 1971-09-13 |
| JPS5341156B1 (US07714131-20100511-C00001.png) | 1978-10-31 |
| NL7102897A (US07714131-20100511-C00001.png) | 1971-09-14 |
| CH521347A (fr) | 1972-04-15 |
| AT303042B (de) | 1972-11-10 |
| ZA711602B (en) | 1971-11-24 |
| ES389180A1 (es) | 1973-06-01 |
| FR2081572B1 (US07714131-20100511-C00001.png) | 1973-04-06 |
| FR2081572A1 (US07714131-20100511-C00001.png) | 1971-12-10 |
| FI49034B (US07714131-20100511-C00001.png) | 1974-12-02 |
| GB1285016A (en) | 1972-08-09 |
| DE2112026A1 (de) | 1971-09-23 |
| FI49034C (fi) | 1975-03-10 |
| DE2112026B2 (de) | 1979-03-08 |
| NO133400C (US07714131-20100511-C00001.png) | 1976-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |