DE2001604C2 - Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung - Google Patents

Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung

Info

Publication number
DE2001604C2
DE2001604C2 DE19702001604 DE2001604A DE2001604C2 DE 2001604 C2 DE2001604 C2 DE 2001604C2 DE 19702001604 DE19702001604 DE 19702001604 DE 2001604 A DE2001604 A DE 2001604A DE 2001604 C2 DE2001604 C2 DE 2001604C2
Authority
DE
Germany
Prior art keywords
polyethylene glycol
solution
oxytetracycline
molecular weight
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19702001604
Other languages
German (de)
English (en)
Other versions
DE2001604A1 (de
Inventor
Rolf Ernst Dr. Beutel
Kaethe Christel 7500 Karlsruhe Loehlbach
Helmut Wilhelm Dr. Raaf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer GmbH
Original Assignee
Pfizer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer GmbH filed Critical Pfizer GmbH
Priority to DE19702001604 priority Critical patent/DE2001604C2/de
Priority to GB3700770A priority patent/GB1286351A/en
Priority to JP11947870A priority patent/JPS4935410B1/ja
Priority to FR7100146A priority patent/FR2081434B1/fr
Publication of DE2001604A1 publication Critical patent/DE2001604A1/de
Application granted granted Critical
Publication of DE2001604C2 publication Critical patent/DE2001604C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19702001604 1970-01-15 1970-01-15 Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung Expired DE2001604C2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE19702001604 DE2001604C2 (de) 1970-01-15 1970-01-15 Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung
GB3700770A GB1286351A (en) 1970-01-15 1970-07-30 Oxytetracycline solutions containing polyethylene glycols
JP11947870A JPS4935410B1 (en:Method) 1970-01-15 1970-12-28
FR7100146A FR2081434B1 (en:Method) 1970-01-15 1971-01-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702001604 DE2001604C2 (de) 1970-01-15 1970-01-15 Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung

Publications (2)

Publication Number Publication Date
DE2001604A1 DE2001604A1 (de) 1971-08-19
DE2001604C2 true DE2001604C2 (de) 1983-04-14

Family

ID=5759662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702001604 Expired DE2001604C2 (de) 1970-01-15 1970-01-15 Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung

Country Status (4)

Country Link
JP (1) JPS4935410B1 (en:Method)
DE (1) DE2001604C2 (en:Method)
FR (1) FR2081434B1 (en:Method)
GB (1) GB1286351A (en:Method)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1163197A (en) * 1980-04-10 1984-03-06 Herman Horn Injectable oxytetracycline compositions
US6110905A (en) * 1994-07-09 2000-08-29 Norbrook Laboratories Limited Long-acting oxytetracycline composition
GB9413873D0 (en) * 1994-07-09 1994-08-31 Norbrook Lab Ltd Long-acting oxytetracycline composition
WO2006130599A2 (en) 2005-05-31 2006-12-07 Warsaw Orthopedic, Inc. Compositions and methods for treating a damaged cardiovascular element
US8840933B2 (en) 2006-05-03 2014-09-23 Warsaw Orthopedic, Inc. Method of treating neuronal injury by administering magnesium chloride and PEG
US8945623B2 (en) * 2006-05-03 2015-02-03 Warsaw Orthopedic, Inc. Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use
TW200815020A (en) * 2006-06-15 2008-04-01 Serenex Inc Stabilized tetracycline compositions
US8057458B2 (en) 2006-10-30 2011-11-15 Warsaw Orthopedic, Inc. Method for treating facet pain
US9675696B2 (en) 2006-11-14 2017-06-13 Warsaw Orthopedic, Inc. Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain
US8153112B2 (en) 2007-08-03 2012-04-10 Warsaw Orthopedic, Inc. Compositions and methods for treating cavity conditions
US9078808B2 (en) 2009-03-26 2015-07-14 Warsaw Orthopedic, Inc. Device to deliver magnesium in PEG formulation
US8852566B2 (en) 2009-03-26 2014-10-07 Warsaw Orthopedic, Inc. Compositions and methods for preferential distribution of active agents to injury sites
CA2756924A1 (en) 2009-03-26 2010-09-30 Warsaw Orthopedic, Inc. Methods of identifying potential components for targeted drug delivery compositions
US9244060B2 (en) 2009-03-26 2016-01-26 Warsaw Orthopedic, Inc. Site localization and methods for monitoring treatment of disturbed blood vessels
US8858924B2 (en) 2009-03-26 2014-10-14 Warsaw Orthopedic, Inc. Compositions and methods for treatment of hemorrhage

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3017323A (en) * 1957-07-02 1962-01-16 Pfizer & Co C Therapeutic compositions comprising polyhydric alcohol solutions of tetracycline-type antibiotics

Also Published As

Publication number Publication date
FR2081434B1 (en:Method) 1974-08-30
GB1286351A (en) 1972-08-23
DE2001604A1 (de) 1971-08-19
JPS4935410B1 (en:Method) 1974-09-21
FR2081434A1 (en:Method) 1971-12-03

Similar Documents

Publication Publication Date Title
DE2001604C2 (de) Verwendung von Polyäthylenglykol zur Herstellung von Oxytetracyclinlösungen zur parenteralen, peroralen und lokalen Anwendung
DE1767891C3 (de) Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
DE3042332C2 (en:Method)
EP0806955B1 (de) Enrofloxacin-injektions- oder infusionslösungen
DE2359333A1 (de) Verfahren zur herstellung eines dopapraeparats
DE3222250C2 (en:Method)
DE2515594C3 (de) Verfahren zur Herstellung eines stabilen, topisch aktiven Geles
DE2042323A1 (de) Blutbildendes Präparat
DE2603046C2 (de) 4'α- und 4'β-Amino-4'-desoxy-oleandrine, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate
DE2202690C3 (de) Antibiotikum 27 706 RP, Verfahren zu dessen Herstellung und Arzneimittel
DE2935776C2 (en:Method)
DE2501805A1 (de) Arzneimittelzubereitungen und verfahren zu ihrer herstellung
DE1795001A1 (de) Alkylsulfatsalze des 1-(p-Chlorbenzhydryl)-4-methylhomopiperazins
EP0108248B2 (de) Lösungsvermittlerfreie, wässrige Nitroglycerinlösung
DE2655130B2 (de) Eine praktisch lösungsmittelfreie Kristallform des Cefacetril-Natriumsalzes
DE1001455C2 (de) Verfahren zur Herstellung geschmacksfreier Zubereitungen basischer Antihistaminika
DE1620177B2 (de) N-(2-Hydroxyäthyl) -piperazinocarboxymethyl-te tr acy elin, dessen pharmakologisch verwendbaren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2357864A1 (de) Nicotinsaure salze von derivaten des biguanids, verfahren zu ihrer herstellung, sowie diese salze enthaltende arzneimittel
AT311553B (de) Verfahren zur Herstellung von Antibiotika
DE2500599A1 (de) Vincamin-2-ketoglutarat und verfahren zu seiner herstellung
DE2241076B2 (de) Tetracyclinkomplex und dessen Salze, Verfahren zu dessen Herstellung und diesen Komplex enthaltende pharmazeutische Zusammensetzungen
DE3745094B4 (de) Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung
AT347033B (de) Verfahren zum herstellen eines wasserloeslichen tetracyclinderivates
DE3881707T2 (de) Minoxidil-gel.
DE1924174C3 (de) Magnesiumorotatglycinate

Legal Events

Date Code Title Description
D2 Grant after examination
8364 No opposition during term of opposition