DE19954421A1 - Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen - Google Patents

Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen

Info

Publication number
DE19954421A1
DE19954421A1 DE19954421A DE19954421A DE19954421A1 DE 19954421 A1 DE19954421 A1 DE 19954421A1 DE 19954421 A DE19954421 A DE 19954421A DE 19954421 A DE19954421 A DE 19954421A DE 19954421 A1 DE19954421 A1 DE 19954421A1
Authority
DE
Germany
Prior art keywords
film
layer
release
polymer
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19954421A
Other languages
German (de)
English (en)
Inventor
Karin Ludwig
Markus Krumme
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Priority to DE19954421A priority Critical patent/DE19954421A1/de
Priority to ES00975993T priority patent/ES2260068T3/es
Priority to EP00975993A priority patent/EP1227802B1/de
Priority to AT05026782T priority patent/ATE465722T1/de
Priority to ES05026782T priority patent/ES2344954T3/es
Priority to IL14957200A priority patent/IL149572A0/xx
Priority to PT00975993T priority patent/PT1227802E/pt
Priority to US10/129,837 priority patent/US7037526B1/en
Priority to KR1020027006105A priority patent/KR100677837B1/ko
Priority to CNB008167354A priority patent/CN100531724C/zh
Priority to DK00975993T priority patent/DK1227802T3/da
Priority to AU13916/01A priority patent/AU777870B2/en
Priority to AT00975993T priority patent/ATE320245T1/de
Priority to EP05026782A priority patent/EP1634587B1/de
Priority to DE50015917T priority patent/DE50015917D1/de
Priority to DE50012412T priority patent/DE50012412D1/de
Priority to CA002391393A priority patent/CA2391393C/en
Priority to JP2001537927A priority patent/JP4825385B2/ja
Priority to PCT/EP2000/010861 priority patent/WO2001035934A1/de
Publication of DE19954421A1 publication Critical patent/DE19954421A1/de
Priority to IL149572A priority patent/IL149572A/en
Priority to US11/408,958 priority patent/US9084731B2/en
Priority to CY20061100798T priority patent/CY1105051T1/el
Priority to JP2011051364A priority patent/JP2011144193A/ja
Priority to US14/742,171 priority patent/US9211267B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Laminated Bodies (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19954421A 1999-11-12 1999-11-12 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen Withdrawn DE19954421A1 (de)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DE19954421A DE19954421A1 (de) 1999-11-12 1999-11-12 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
AU13916/01A AU777870B2 (en) 1999-11-12 2000-11-03 Film preparation for biphasic release of pharmacologically active or other substances
DE50015917T DE50015917D1 (de) 1999-11-12 2000-11-03 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
EP05026782A EP1634587B1 (de) 1999-11-12 2000-11-03 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
ES05026782T ES2344954T3 (es) 1999-11-12 2000-11-03 Preparacion en forma de pelicula para la liberacion bifasica de sustancias farmacologicamente activas u otras.
EP00975993A EP1227802B1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen
PT00975993T PT1227802E (pt) 1999-11-12 2000-11-03 Prepacao de pelicula para libertacao bifasica de substancias farmacologicamente activas ou outras
US10/129,837 US7037526B1 (en) 1999-11-12 2000-11-03 Film preparation for biphasic release of pharmacologically active or other substances
DE50012412T DE50012412D1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen
CNB008167354A CN100531724C (zh) 1999-11-12 2000-11-03 双相释放药理活性物质或其它物质的薄膜形制剂
DK00975993T DK1227802T3 (da) 1999-11-12 2000-11-03 Filmformigt præparat til bifase-frigivelse af farmakologisk aktive substanser eller andre substanser
ES00975993T ES2260068T3 (es) 1999-11-12 2000-11-03 Preparacion en forma de lamina para la liberacion bifasica de sustancias farmacologicamente activas u otras.
AT00975993T ATE320245T1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen
AT05026782T ATE465722T1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen
IL14957200A IL149572A0 (en) 1999-11-12 2000-11-03 Film preparation for biphasic release of pharmacologically active or other substances
KR1020027006105A KR100677837B1 (ko) 1999-11-12 2000-11-03 약리학적으로 활성이 있는 물질 또는 이와 다른 물질을 2상 방출하기 위한 필름 형태의 약제
CA002391393A CA2391393C (en) 1999-11-12 2000-11-03 Film preparation for biphasic release of pharmacologically active or other substances
JP2001537927A JP4825385B2 (ja) 1999-11-12 2000-11-03 薬理学的活性物質またはその他の物質の二相放出用薄膜製剤
PCT/EP2000/010861 WO2001035934A1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen
IL149572A IL149572A (en) 1999-11-12 2002-05-09 Thin coating preparation for biphasic release of pharmacologically or other active substances
US11/408,958 US9084731B2 (en) 1999-11-12 2006-04-24 Preparation in film form for biphasic release of pharmacologically active or other substances
CY20061100798T CY1105051T1 (el) 1999-11-12 2006-06-14 Παρασκευασμα σε μορφη υμενιου για τη διφασικη απελευθερωση ουσιων με φαρμακολογικη δραση ή αλλων ουσιων
JP2011051364A JP2011144193A (ja) 1999-11-12 2011-03-09 薬理学的活性物質またはその他の物質の二相放出用薄膜製剤
US14/742,171 US9211267B2 (en) 1999-11-12 2015-06-17 Preparation in film form for biphasic release of pharmacologically active or other substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19954421A DE19954421A1 (de) 1999-11-12 1999-11-12 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen

Publications (1)

Publication Number Publication Date
DE19954421A1 true DE19954421A1 (de) 2001-05-31

Family

ID=7928785

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19954421A Withdrawn DE19954421A1 (de) 1999-11-12 1999-11-12 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
DE50015917T Expired - Lifetime DE50015917D1 (de) 1999-11-12 2000-11-03 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
DE50012412T Expired - Lifetime DE50012412D1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE50015917T Expired - Lifetime DE50015917D1 (de) 1999-11-12 2000-11-03 Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
DE50012412T Expired - Lifetime DE50012412D1 (de) 1999-11-12 2000-11-03 Filmförmige zubereitung zur biphasigen freisetzung pharmakologisch wirksamer oder anderer substanzen

Country Status (15)

Country Link
US (3) US7037526B1 (xx)
EP (2) EP1634587B1 (xx)
JP (2) JP4825385B2 (xx)
KR (1) KR100677837B1 (xx)
CN (1) CN100531724C (xx)
AT (2) ATE320245T1 (xx)
AU (1) AU777870B2 (xx)
CA (1) CA2391393C (xx)
CY (1) CY1105051T1 (xx)
DE (3) DE19954421A1 (xx)
DK (1) DK1227802T3 (xx)
ES (2) ES2260068T3 (xx)
IL (2) IL149572A0 (xx)
PT (1) PT1227802E (xx)
WO (1) WO2001035934A1 (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20307771U1 (de) * 2003-05-19 2004-09-23 Cofresco Frischhalteprodukte Gmbh & Co. Kg Beschichtung und Beutel

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DE19954421A1 (de) 1999-11-12 2001-05-31 Lohmann Therapie Syst Lts Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
CA2493881C (en) * 2002-05-16 2011-07-12 Kyukyu Pharmaceutical Co., Ltd. Rapidly soluble film-shaped preparation
US20040131662A1 (en) 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US20040191302A1 (en) 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US9561182B2 (en) 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US8999372B2 (en) 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20050186257A1 (en) * 2004-02-20 2005-08-25 Todd Manegold Dissolvable film and method of manufacture
KR20190104428A (ko) 2005-12-29 2019-09-09 안트로제네시스 코포레이션 태반 줄기 세포 집단
US8455250B2 (en) 2005-12-29 2013-06-04 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US20070175484A1 (en) * 2006-01-30 2007-08-02 Staab Robert J Condoms for beneficial agents delivery
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
KR20210022148A (ko) 2007-09-28 2021-03-02 안트로제네시스 코포레이션 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법
MX2011001991A (es) 2008-08-20 2011-03-29 Anthrogenesis Corp Tratamiento de la apoplejia utilizando celulas placentarias aisladas.
EP3539380A3 (en) 2008-08-20 2019-12-18 Celularity, Inc. Improved cell composition and methods of making the same
DK2367932T3 (da) 2008-11-19 2019-09-23 Celularity Inc Amnion-afledte adhærente celler
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
DK2952191T3 (en) 2009-06-12 2018-12-10 Sunovion Pharmaceuticals Inc Sublingual apomorphine
ES2646750T3 (es) 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
EP2593542B1 (en) 2010-07-13 2018-01-03 Anthrogenesis Corporation Methods of generating natural killer cells
KR101802553B1 (ko) * 2010-09-23 2017-11-28 모노졸 알엑스, 엘엘씨 제약 생성물을 패키지 표면 상에 직접적으로 형성시키는 방법 및 시스템
CA3116942A1 (en) 2010-12-16 2012-06-21 Sunovion Pharmaceuticals Inc. Sublingual films comprising apomorphine and an organic base
JP5831239B2 (ja) 2012-01-16 2015-12-09 Tdk株式会社 バスバー及び電子機器
AU2012385956B2 (en) 2012-07-23 2017-03-30 Crayola, Llc Dissolvable films and methods of using the same
CN105142651A (zh) 2013-02-05 2015-12-09 人类起源公司 来自胎盘的自然杀伤细胞
EP3254112B1 (en) * 2015-02-05 2023-10-11 ATH (Australia) Limited Formulations comprising mercury-containing reagents for detecting disease
CA3127926A1 (en) 2015-04-21 2016-10-27 Sunovion Pharmaceuticals Inc. Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
CN105997958B (zh) * 2016-07-12 2019-03-26 中国人民解放军白求恩医务士官学校 一种口腔外用制剂及其制备方法
US11439162B2 (en) * 2018-10-11 2022-09-13 Vitiprints, LLC Dissolvable composition having indicia
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20307771U1 (de) * 2003-05-19 2004-09-23 Cofresco Frischhalteprodukte Gmbh & Co. Kg Beschichtung und Beutel

Also Published As

Publication number Publication date
US7037526B1 (en) 2006-05-02
ATE320245T1 (de) 2006-04-15
JP2003514009A (ja) 2003-04-15
CN100531724C (zh) 2009-08-26
EP1227802A1 (de) 2002-08-07
AU777870B2 (en) 2004-11-04
CA2391393A1 (en) 2001-05-25
IL149572A (en) 2007-08-19
ES2344954T3 (es) 2010-09-10
ES2260068T3 (es) 2006-11-01
US20060198878A1 (en) 2006-09-07
US20150272904A1 (en) 2015-10-01
JP4825385B2 (ja) 2011-11-30
CN1407888A (zh) 2003-04-02
US9084731B2 (en) 2015-07-21
EP1634587B1 (de) 2010-04-28
AU1391601A (en) 2001-05-30
DE50015917D1 (de) 2010-06-10
DK1227802T3 (da) 2006-07-24
ATE465722T1 (de) 2010-05-15
EP1634587A2 (de) 2006-03-15
KR20020058008A (ko) 2002-07-12
CA2391393C (en) 2008-07-15
EP1227802B1 (de) 2006-03-15
EP1634587A3 (de) 2008-09-17
IL149572A0 (en) 2002-11-10
WO2001035934A1 (de) 2001-05-25
PT1227802E (pt) 2006-08-31
JP2011144193A (ja) 2011-07-28
US9211267B2 (en) 2015-12-15
DE50012412D1 (de) 2006-05-11
CY1105051T1 (el) 2009-11-04
KR100677837B1 (ko) 2007-02-05

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Legal Events

Date Code Title Description
ON Later submitted papers
OP8 Request for examination as to paragraph 44 patent law
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20120601