DE19940130A1 - Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung - Google Patents
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen AnwendungInfo
- Publication number
- DE19940130A1 DE19940130A1 DE19940130A DE19940130A DE19940130A1 DE 19940130 A1 DE19940130 A1 DE 19940130A1 DE 19940130 A DE19940130 A DE 19940130A DE 19940130 A DE19940130 A DE 19940130A DE 19940130 A1 DE19940130 A1 DE 19940130A1
- Authority
- DE
- Germany
- Prior art keywords
- compound
- inhibitors
- pharmaceutical
- dipeptidyl peptidase
- cosmetic composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/06104—Dipeptides with the first amino acid being acidic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyethers (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19940130A DE19940130A1 (de) | 1999-08-24 | 1999-08-24 | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| CN00811936A CN1370181A (zh) | 1999-08-24 | 2000-08-20 | 局部使用的新的二肽基肽酶iv效应物 |
| EP07104464A EP1792910A2 (de) | 1999-08-24 | 2000-08-20 | Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| JP2001518409A JP2003519099A (ja) | 1999-08-24 | 2000-08-20 | 局所使用されるジペプチジルペプチダーゼｉｖの新しいエフェクター |
| BR0013577-1A BR0013577A (pt) | 1999-08-24 | 2000-08-20 | Efetores de dipeptidil peptidase iv para uso tópico |
| MXPA02001800A MXPA02001800A (es) | 1999-08-24 | 2000-08-20 | Nuevos efectores de dipeptidilpeptidasa iv para uso topico. |
| PT00953186T PT1206485E (pt) | 1999-08-24 | 2000-08-20 | Novos efectores da dipeptidil peptidase iv para a utilização tópica |
| AU65721/00A AU769404B2 (en) | 1999-08-24 | 2000-08-20 | New effectors of dipeptidyl peptidase IV for topical use |
| IL14817000A IL148170A0 (en) | 1999-08-24 | 2000-08-20 | Amino acid derivatives which influence the activity of dipeptidyl peptidase iv and pharmaceutical compositions containing the same |
| DE50014187T DE50014187D1 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
| PCT/EP2000/008118 WO2001014318A2 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
| AT00953186T ATE357455T1 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
| EP00953186A EP1206485B1 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
| ES00953186T ES2282130T3 (es) | 1999-08-24 | 2000-08-20 | Nuevos efectores de la dipeptidil peptidasa iv para la aplicacion topica. |
| NZ528770A NZ528770A (en) | 1999-08-24 | 2000-08-20 | New effectors of dipeptidyl peptidase IV for topical use |
| CA002379875A CA2379875A1 (en) | 1999-08-24 | 2000-08-20 | New effectors of dipeptidyl peptidase iv for topical use |
| KR1020027002338A KR20020040787A (ko) | 1999-08-24 | 2000-08-20 | 디펩티딜 펩티다제 ⅳ의 국소용 신규 효능제 |
| ZA200200794A ZA200200794B (en) | 1999-08-24 | 2002-01-29 | Effectors of dipeptidyl peptidase IV for topical use. |
| NO20020858A NO20020858L (no) | 1999-08-24 | 2002-02-22 | Nye effektorer av dipeptidyl peptidase IV for topisk anvendelse |
| US10/082,001 US6949515B2 (en) | 1999-08-24 | 2002-02-22 | Effectors of dipeptidyl peptidase IV for topical use |
| US11/069,926 US7335645B2 (en) | 1999-08-24 | 2005-03-01 | Effectors of dipeptidyl peptidase IV for topical use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19940130A DE19940130A1 (de) | 1999-08-24 | 1999-08-24 | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19940130A1 true DE19940130A1 (de) | 2001-03-01 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19940130A Withdrawn DE19940130A1 (de) | 1999-08-24 | 1999-08-24 | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| DE50014187T Expired - Fee Related DE50014187D1 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50014187T Expired - Fee Related DE50014187D1 (de) | 1999-08-24 | 2000-08-20 | Neue effektoren der dipeptidyl peptidase iv zur topischen anwendung |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6949515B2 (enExample) |
| EP (2) | EP1792910A2 (enExample) |
| JP (1) | JP2003519099A (enExample) |
| KR (1) | KR20020040787A (enExample) |
| CN (1) | CN1370181A (enExample) |
| AT (1) | ATE357455T1 (enExample) |
| AU (1) | AU769404B2 (enExample) |
| BR (1) | BR0013577A (enExample) |
| CA (1) | CA2379875A1 (enExample) |
| DE (2) | DE19940130A1 (enExample) |
| ES (1) | ES2282130T3 (enExample) |
| IL (1) | IL148170A0 (enExample) |
| MX (1) | MXPA02001800A (enExample) |
| NO (1) | NO20020858L (enExample) |
| NZ (1) | NZ528770A (enExample) |
| PT (1) | PT1206485E (enExample) |
| WO (1) | WO2001014318A2 (enExample) |
| ZA (1) | ZA200200794B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001081304A1 (en) * | 2000-04-26 | 2001-11-01 | Ferring Bv | Inhibitors of dipeptidyl peptidase iv |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999038501A2 (en) | 1998-02-02 | 1999-08-05 | Trustees Of Tufts College | Method of regulating glucose metabolism, and reagents related thereto |
| US6979697B1 (en) | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
| WO2003002553A2 (en) | 2001-06-27 | 2003-01-09 | Smithkline Beecham Corporation | Fluoropyrrolidines as dipeptidyl peptidase inhibitors |
| IL158923A0 (en) | 2001-06-27 | 2004-05-12 | Smithkline Beecham Corp | Fluoropyrrolidines as dipeptidyl peptidase inhibitors |
| ATE380175T1 (de) | 2001-06-27 | 2007-12-15 | Smithkline Beecham Corp | Pyrrolidine als dipeptidyl peptidase inhibitoren |
| US7368421B2 (en) * | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
| AU2002360453C1 (en) | 2001-11-26 | 2009-06-18 | The Brigham And Women's Hospital, Inc. | Methods for treating autoimmune disorders, and reagents related thereto |
| JP4771661B2 (ja) | 2001-11-26 | 2011-09-14 | トラスティーズ オブ タフツ カレッジ | Ｐｏｓｔ−プロリン開裂酵素の擬ペプチド性阻害剤 |
| US7550590B2 (en) | 2003-03-25 | 2009-06-23 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| ZA200508439B (en) | 2003-05-05 | 2007-03-28 | Probiodrug Ag | Medical use of inhibitors of glutaminyl and glutamate cyclases |
| WO2004099134A2 (en) * | 2003-05-05 | 2004-11-18 | Prosidion Ltd. | Glutaminyl based dp iv-inhibitors |
| JP2007511467A (ja) | 2003-05-14 | 2007-05-10 | タケダ サン ディエゴ インコーポレイテッド | ジペプチジルペプチダーゼインヒビター |
| WO2005016911A1 (en) | 2003-08-13 | 2005-02-24 | Takeda Pharmaceutical Company Limited | 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors |
| US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
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- 2000-08-20 WO PCT/EP2000/008118 patent/WO2001014318A2/de not_active Ceased
- 2000-08-20 PT PT00953186T patent/PT1206485E/pt unknown
- 2000-08-20 EP EP07104464A patent/EP1792910A2/de not_active Withdrawn
- 2000-08-20 CN CN00811936A patent/CN1370181A/zh active Pending
- 2000-08-20 JP JP2001518409A patent/JP2003519099A/ja not_active Withdrawn
- 2000-08-20 EP EP00953186A patent/EP1206485B1/de not_active Expired - Lifetime
- 2000-08-20 BR BR0013577-1A patent/BR0013577A/pt not_active Application Discontinuation
- 2000-08-20 AT AT00953186T patent/ATE357455T1/de not_active IP Right Cessation
- 2000-08-20 CA CA002379875A patent/CA2379875A1/en not_active Abandoned
- 2000-08-20 DE DE50014187T patent/DE50014187D1/de not_active Expired - Fee Related
- 2000-08-20 MX MXPA02001800A patent/MXPA02001800A/es unknown
- 2000-08-20 NZ NZ528770A patent/NZ528770A/en unknown
- 2000-08-20 AU AU65721/00A patent/AU769404B2/en not_active Ceased
- 2000-08-20 ES ES00953186T patent/ES2282130T3/es not_active Expired - Lifetime
- 2000-08-20 KR KR1020027002338A patent/KR20020040787A/ko not_active Withdrawn
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- 2002-02-22 US US10/082,001 patent/US6949515B2/en not_active Expired - Fee Related
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001081304A1 (en) * | 2000-04-26 | 2001-11-01 | Ferring Bv | Inhibitors of dipeptidyl peptidase iv |
| EP1693365A1 (en) * | 2000-04-26 | 2006-08-23 | Ferring B.V. | Inhibitors of dipeptidyl peptidase IV |
| US7189728B2 (en) | 2000-04-26 | 2007-03-13 | Ferring, Bv | Inhibitors of dipeptidyl peptidase IV |
Also Published As
| Publication number | Publication date |
|---|---|
| IL148170A0 (en) | 2002-09-12 |
| DE50014187D1 (de) | 2007-05-03 |
| AU6572100A (en) | 2001-03-19 |
| US20020165164A1 (en) | 2002-11-07 |
| US6949515B2 (en) | 2005-09-27 |
| EP1206485A2 (de) | 2002-05-22 |
| BR0013577A (pt) | 2002-04-30 |
| NO20020858D0 (no) | 2002-02-22 |
| EP1206485B1 (de) | 2007-03-21 |
| KR20020040787A (ko) | 2002-05-30 |
| PT1206485E (pt) | 2007-05-31 |
| AU769404B2 (en) | 2004-01-29 |
| ES2282130T3 (es) | 2007-10-16 |
| ZA200200794B (en) | 2003-03-26 |
| MXPA02001800A (es) | 2003-09-25 |
| WO2001014318A2 (de) | 2001-03-01 |
| CN1370181A (zh) | 2002-09-18 |
| NO20020858L (no) | 2002-02-22 |
| US7335645B2 (en) | 2008-02-26 |
| US20050209159A1 (en) | 2005-09-22 |
| CA2379875A1 (en) | 2001-03-01 |
| US20030092630A2 (en) | 2003-05-15 |
| EP1792910A2 (de) | 2007-06-06 |
| ATE357455T1 (de) | 2007-04-15 |
| WO2001014318A3 (de) | 2001-11-01 |
| NZ528770A (en) | 2005-02-25 |
| JP2003519099A (ja) | 2003-06-17 |
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