BR9306190A - Composto composiçao farmacéutica e processo para tratar um indivíduo sofrendo de um distúrbio cognitivo ou uma deficiéncia na atençao ou estímulo - Google Patents
Composto composiçao farmacéutica e processo para tratar um indivíduo sofrendo de um distúrbio cognitivo ou uma deficiéncia na atençao ou estímuloInfo
- Publication number
- BR9306190A BR9306190A BR9306190A BR9306190A BR9306190A BR 9306190 A BR9306190 A BR 9306190A BR 9306190 A BR9306190 A BR 9306190A BR 9306190 A BR9306190 A BR 9306190A BR 9306190 A BR9306190 A BR 9306190A
- Authority
- BR
- Brazil
- Prior art keywords
- stimulus
- treat
- pharmaceutical composition
- cognitive impairment
- individual suffering
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86265792A | 1992-04-01 | 1992-04-01 | |
| PCT/US1993/003104 WO1993020061A1 (en) | 1992-04-01 | 1993-03-31 | 4-[4'-piperidinyl or 3'-pirrolidinyl] substituted imidazoles as h3-receptor antagonists and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9306190A true BR9306190A (pt) | 1998-06-23 |
Family
ID=25338976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9306190A BR9306190A (pt) | 1992-04-01 | 1993-03-31 | Composto composiçao farmacéutica e processo para tratar um indivíduo sofrendo de um distúrbio cognitivo ou uma deficiéncia na atençao ou estímulo |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5633382A (pt) |
| EP (1) | EP0633882A1 (pt) |
| JP (1) | JPH07509219A (pt) |
| KR (1) | KR950700902A (pt) |
| AU (1) | AU3944593A (pt) |
| BR (1) | BR9306190A (pt) |
| CA (1) | CA2133461A1 (pt) |
| FI (1) | FI944605A (pt) |
| HU (1) | HUT71353A (pt) |
| NO (1) | NO943687L (pt) |
| RU (1) | RU94044337A (pt) |
| SK (1) | SK118794A3 (pt) |
| WO (1) | WO1993020061A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07121939B2 (ja) * | 1991-12-18 | 1995-12-25 | シェリング・コーポレーション | 窒素含有４または５員複素環で置換されたイミダゾリルまたはイミダゾイルアルキル化合物 |
| US6407132B1 (en) | 1997-07-25 | 2002-06-18 | James Black Foundation Limited | Substituted imidazole derivatives and their use as histamine H3 receptor ligands |
| EP1027050B1 (en) * | 1997-10-27 | 2004-01-14 | Takeda Chemical Industries, Ltd. | 1,3-thiazoles as adenosine a3 receptor antagonists for the treatment of allergy, asthma and diabetes |
| EP1147092A1 (en) | 1999-01-18 | 2001-10-24 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6908926B1 (en) | 1999-04-16 | 2005-06-21 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| AU3957600A (en) * | 1999-04-26 | 2000-11-10 | Boehringer Ingelheim International Gmbh | Piperidyl-imidazole derivatives, their preparations and therapeutic uses |
| DE19940130A1 (de) | 1999-08-24 | 2001-03-01 | Probiodrug Ges Fuer Arzneim | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| US6610721B2 (en) | 2000-03-17 | 2003-08-26 | Novo Nordisk A/S | Imidazo heterocyclic compounds |
| US6437147B1 (en) | 2000-03-17 | 2002-08-20 | Novo Nordisk | Imidazole compounds |
| MXPA03001268A (es) | 2000-08-08 | 2004-09-06 | Johnson & Johnson | Ariloxipiperidinas sin imidazol. |
| DE60118754T2 (de) | 2000-08-08 | 2007-01-11 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclische verbindungen als h3 rezeptor liganden |
| DE60117814T2 (de) | 2000-08-08 | 2006-11-02 | Ortho-Mcneil Pharmaceutical, Inc. | Nicht-imidazol aryloxyalkylamine als h3 rezeptor liganden |
| FR2818978B1 (fr) * | 2000-12-28 | 2003-02-28 | Sod Conseils Rech Applic | Modulateurs de canaux sodiques derives de 2-piperidylimidazoles |
| US20030130199A1 (en) | 2001-06-27 | 2003-07-10 | Von Hoersten Stephan | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents |
| US6844316B2 (en) | 2001-09-06 | 2005-01-18 | Probiodrug Ag | Inhibitors of dipeptidyl peptidase I |
| RU2366652C2 (ru) * | 2002-02-01 | 2009-09-10 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Амиды аминоалкилзамещенных азетидинов, пирролидинов, пиперидинов и азепанов |
| US7332508B2 (en) * | 2002-12-18 | 2008-02-19 | Novo Nordisk A/S | Substituted homopiperidine, piperidine or pyrrolidine derivatives |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| ZA200508439B (en) | 2003-05-05 | 2007-03-28 | Probiodrug Ag | Medical use of inhibitors of glutaminyl and glutamate cyclases |
| DE202004021723U1 (de) * | 2003-05-05 | 2010-07-15 | Probiodrug Ag | Medizinische Verwendung von Hemmern von Glutaminyl- und Glutamatcyclasen |
| EP1620082B9 (en) * | 2003-05-05 | 2010-08-25 | Probiodrug AG | Medical use of inhibitors of glutaminyl and glutamate cyclases for treating alzheimer's disease and down syndrome |
| JP5707014B2 (ja) | 2003-10-15 | 2015-04-22 | プロビオドルグ エージー | グルタミニル、及びグルタミン酸シクラーゼのエフェクターの使用 |
| EP1713780B1 (en) | 2004-02-05 | 2012-01-18 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
| US20080139614A1 (en) * | 2004-11-23 | 2008-06-12 | Seabrook Guy R | Treatment Of Stroke With Histamine H3 Inverse Agonists Or Histamine H3 Antagonists |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| JP2017100949A (ja) * | 2014-04-01 | 2017-06-08 | 大日本住友製薬株式会社 | ５員環ヘテロアリール誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2579596B1 (fr) * | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| FR2630328B1 (fr) * | 1988-04-22 | 1990-08-24 | Inst Nat Sante Rech Med | Derive de l'histamine, sa preparation et son application en therapeutique |
| FR2661909B1 (fr) * | 1990-05-09 | 1997-08-14 | Inst Nat Sante Rech Med | Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation. |
| FR2671083B1 (fr) * | 1990-12-31 | 1994-12-23 | Inst Nat Sante Rech Med | Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques. |
| US5070101A (en) * | 1991-02-14 | 1991-12-03 | Mount Sinai School Of Medicine Of The City University Of New York | Method and pharmaceutical composition for the treatment of schizophrenia |
-
1993
- 1993-03-31 JP JP5517715A patent/JPH07509219A/ja active Pending
- 1993-03-31 CA CA002133461A patent/CA2133461A1/en not_active Abandoned
- 1993-03-31 RU RU94044337/04A patent/RU94044337A/ru unknown
- 1993-03-31 HU HU9402827A patent/HUT71353A/hu unknown
- 1993-03-31 EP EP93908724A patent/EP0633882A1/en not_active Withdrawn
- 1993-03-31 WO PCT/US1993/003104 patent/WO1993020061A1/en not_active Application Discontinuation
- 1993-03-31 AU AU39445/93A patent/AU3944593A/en not_active Abandoned
- 1993-03-31 SK SK1187-94A patent/SK118794A3/sk unknown
- 1993-03-31 BR BR9306190A patent/BR9306190A/pt not_active Application Discontinuation
-
1994
- 1994-06-15 US US08/259,926 patent/US5633382A/en not_active Expired - Lifetime
- 1994-09-30 KR KR1019940703408A patent/KR950700902A/ko not_active Application Discontinuation
- 1994-10-03 NO NO943687A patent/NO943687L/no unknown
- 1994-10-03 FI FI944605A patent/FI944605A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU94044337A (ru) | 1996-08-10 |
| CA2133461A1 (en) | 1993-10-14 |
| KR950700902A (ko) | 1995-02-20 |
| FI944605A (fi) | 1994-11-30 |
| FI944605A0 (fi) | 1994-10-03 |
| WO1993020061A1 (en) | 1993-10-14 |
| HUT71353A (en) | 1995-11-28 |
| EP0633882A1 (en) | 1995-01-18 |
| NO943687L (no) | 1994-11-21 |
| SK118794A3 (en) | 1995-06-07 |
| NO943687D0 (no) | 1994-10-03 |
| US5633382A (en) | 1997-05-27 |
| JPH07509219A (ja) | 1995-10-12 |
| HU9402827D0 (en) | 1994-12-28 |
| AU3944593A (en) | 1993-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA7 | Application deemed withdrawn (art. 18 par. 1 of law 5772/71) - being contrary to morals, good customs and public security, order and health |