NO943687D0 - 4-(4'-piperidinyl eller 3'-pirrolidinyl) substituerte imidazoler som H3-reseptorantagonister og terapeutiske anvendelser derav - Google Patents
4-(4'-piperidinyl eller 3'-pirrolidinyl) substituerte imidazoler som H3-reseptorantagonister og terapeutiske anvendelser deravInfo
- Publication number
- NO943687D0 NO943687D0 NO943687A NO943687A NO943687D0 NO 943687 D0 NO943687 D0 NO 943687D0 NO 943687 A NO943687 A NO 943687A NO 943687 A NO943687 A NO 943687A NO 943687 D0 NO943687 D0 NO 943687D0
- Authority
- NO
- Norway
- Prior art keywords
- pyrrolidinyl
- piperidinyl
- receptor antagonists
- therapeutic uses
- substituted imidazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86265792A | 1992-04-01 | 1992-04-01 | |
| PCT/US1993/003104 WO1993020061A1 (en) | 1992-04-01 | 1993-03-31 | 4-[4'-piperidinyl or 3'-pirrolidinyl] substituted imidazoles as h3-receptor antagonists and therapeutic uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO943687D0 true NO943687D0 (no) | 1994-10-03 |
| NO943687L NO943687L (no) | 1994-11-21 |
Family
ID=25338976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO943687A NO943687L (no) | 1992-04-01 | 1994-10-03 | 4-(4'-piperidinyl eller 3'-pirrolidinyl) substituerte imidazoler som H3-reseptorantagonister og terapeutiske anvendelser derav |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5633382A (no) |
| EP (1) | EP0633882A1 (no) |
| JP (1) | JPH07509219A (no) |
| KR (1) | KR950700902A (no) |
| AU (1) | AU3944593A (no) |
| BR (1) | BR9306190A (no) |
| CA (1) | CA2133461A1 (no) |
| FI (1) | FI944605A (no) |
| HU (1) | HUT71353A (no) |
| NO (1) | NO943687L (no) |
| RU (1) | RU94044337A (no) |
| SK (1) | SK118794A3 (no) |
| WO (1) | WO1993020061A1 (no) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2129679C (en) * | 1991-12-18 | 2000-05-09 | Neng-Yang Shih | Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring |
| US6407132B1 (en) | 1997-07-25 | 2002-06-18 | James Black Foundation Limited | Substituted imidazole derivatives and their use as histamine H3 receptor ligands |
| US6436966B1 (en) * | 1997-10-27 | 2002-08-20 | Takeda Chemical Ind., Ltd. | Adenosine A3 receptor antagonists |
| AU3033100A (en) | 1999-01-18 | 2000-08-01 | Boehringer Ingelheim International Gmbh | Substituted imidazoles, their preparation and use |
| US6908926B1 (en) | 1999-04-16 | 2005-06-21 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| AU3957600A (en) * | 1999-04-26 | 2000-11-10 | Boehringer Ingelheim International Gmbh | Piperidyl-imidazole derivatives, their preparations and therapeutic uses |
| DE19940130A1 (de) | 1999-08-24 | 2001-03-01 | Probiodrug Ges Fuer Arzneim | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
| US6610721B2 (en) | 2000-03-17 | 2003-08-26 | Novo Nordisk A/S | Imidazo heterocyclic compounds |
| US6437147B1 (en) | 2000-03-17 | 2002-08-20 | Novo Nordisk | Imidazole compounds |
| ES2261454T3 (es) | 2000-08-08 | 2006-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Compuestos biciclicos como ligandos del receptor h3. |
| ATE319696T1 (de) | 2000-08-08 | 2006-03-15 | Ortho Mcneil Pharm Inc | Nicht-imidazol aryloxyalkylamine als h3 rezeptor liganden |
| AU8112101A (en) | 2000-08-08 | 2002-02-18 | Ortho Mcneil Pharm Inc | Non-imidazole aryloxypiperidines |
| FR2818978B1 (fr) * | 2000-12-28 | 2003-02-28 | Sod Conseils Rech Applic | Modulateurs de canaux sodiques derives de 2-piperidylimidazoles |
| US20030130199A1 (en) | 2001-06-27 | 2003-07-10 | Von Hoersten Stephan | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents |
| US6844316B2 (en) | 2001-09-06 | 2005-01-18 | Probiodrug Ag | Inhibitors of dipeptidyl peptidase I |
| CN1625554A (zh) * | 2002-02-01 | 2005-06-08 | 诺沃挪第克公司 | 氨基烷基－取代的氮杂环丁烷、吡咯烷、哌啶与氮杂环庚烷的酰胺 |
| US7332508B2 (en) * | 2002-12-18 | 2008-02-19 | Novo Nordisk A/S | Substituted homopiperidine, piperidine or pyrrolidine derivatives |
| DE602004026289D1 (de) | 2003-05-05 | 2010-05-12 | Probiodrug Ag | Glutaminylcyclase-hemmer |
| EP1620082B9 (en) * | 2003-05-05 | 2010-08-25 | Probiodrug AG | Medical use of inhibitors of glutaminyl and glutamate cyclases for treating alzheimer's disease and down syndrome |
| CN101837127A (zh) | 2003-05-05 | 2010-09-22 | 前体生物药物股份公司 | 谷氨酰胺酰基和谷氨酸环化酶效应物的应用 |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| WO2005039548A2 (en) | 2003-10-15 | 2005-05-06 | Probiodrug Ag | Use of effectors of glutaminyl and glutamate cyclases |
| AU2005210004B2 (en) | 2004-02-05 | 2010-10-28 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| US20080139614A1 (en) * | 2004-11-23 | 2008-06-12 | Seabrook Guy R | Treatment Of Stroke With Histamine H3 Inverse Agonists Or Histamine H3 Antagonists |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| JP2017100949A (ja) * | 2014-04-01 | 2017-06-08 | 大日本住友製薬株式会社 | ５員環ヘテロアリール誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2579596B1 (fr) * | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| FR2630328B1 (fr) * | 1988-04-22 | 1990-08-24 | Inst Nat Sante Rech Med | Derive de l'histamine, sa preparation et son application en therapeutique |
| FR2661909B1 (fr) * | 1990-05-09 | 1997-08-14 | Inst Nat Sante Rech Med | Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation. |
| FR2671083B1 (fr) * | 1990-12-31 | 1994-12-23 | Inst Nat Sante Rech Med | Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques. |
| US5070101A (en) * | 1991-02-14 | 1991-12-03 | Mount Sinai School Of Medicine Of The City University Of New York | Method and pharmaceutical composition for the treatment of schizophrenia |
-
1993
- 1993-03-31 CA CA002133461A patent/CA2133461A1/en not_active Abandoned
- 1993-03-31 SK SK1187-94A patent/SK118794A3/sk unknown
- 1993-03-31 HU HU9402827A patent/HUT71353A/hu unknown
- 1993-03-31 EP EP93908724A patent/EP0633882A1/en not_active Withdrawn
- 1993-03-31 RU RU94044337/04A patent/RU94044337A/ru unknown
- 1993-03-31 AU AU39445/93A patent/AU3944593A/en not_active Abandoned
- 1993-03-31 WO PCT/US1993/003104 patent/WO1993020061A1/en not_active Application Discontinuation
- 1993-03-31 BR BR9306190A patent/BR9306190A/pt not_active Application Discontinuation
- 1993-03-31 JP JP5517715A patent/JPH07509219A/ja active Pending
-
1994
- 1994-06-15 US US08/259,926 patent/US5633382A/en not_active Expired - Lifetime
- 1994-09-30 KR KR1019940703408A patent/KR950700902A/ko not_active Application Discontinuation
- 1994-10-03 FI FI944605A patent/FI944605A/fi not_active Application Discontinuation
- 1994-10-03 NO NO943687A patent/NO943687L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK118794A3 (en) | 1995-06-07 |
| AU3944593A (en) | 1993-11-08 |
| RU94044337A (ru) | 1996-08-10 |
| FI944605A (fi) | 1994-11-30 |
| BR9306190A (pt) | 1998-06-23 |
| JPH07509219A (ja) | 1995-10-12 |
| EP0633882A1 (en) | 1995-01-18 |
| KR950700902A (ko) | 1995-02-20 |
| HU9402827D0 (en) | 1994-12-28 |
| US5633382A (en) | 1997-05-27 |
| NO943687L (no) | 1994-11-21 |
| CA2133461A1 (en) | 1993-10-14 |
| WO1993020061A1 (en) | 1993-10-14 |
| HUT71353A (en) | 1995-11-28 |
| FI944605A0 (fi) | 1994-10-03 |
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