DE19716154A1 - Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren - Google Patents

Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren

Info

Publication number
DE19716154A1
DE19716154A1 DE19716154A DE19716154A DE19716154A1 DE 19716154 A1 DE19716154 A1 DE 19716154A1 DE 19716154 A DE19716154 A DE 19716154A DE 19716154 A DE19716154 A DE 19716154A DE 19716154 A1 DE19716154 A1 DE 19716154A1
Authority
DE
Germany
Prior art keywords
acid
preparations according
lyophilized preparations
lyophilized
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19716154A
Other languages
German (de)
English (en)
Inventor
Wolfgang Dipl Chem Dr Roedel
Markus Dr Mattern
Gerhard Dr Winter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19716154A priority Critical patent/DE19716154A1/de
Priority to JP54494698A priority patent/JP2001524090A/ja
Priority to CA002288649A priority patent/CA2288649A1/en
Priority to KR1019997009652A priority patent/KR20010006562A/ko
Priority to PCT/EP1998/002131 priority patent/WO1998047490A1/de
Priority to BR9809103-4A priority patent/BR9809103A/pt
Priority to CN98806448A priority patent/CN1261271A/zh
Priority to TR1999/02575T priority patent/TR199902575T2/xx
Priority to AU77585/98A priority patent/AU744777B2/en
Priority to EP98925470A priority patent/EP0975335A1/de
Publication of DE19716154A1 publication Critical patent/DE19716154A1/de
Priority to US10/046,311 priority patent/US20020103126A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE19716154A 1997-04-18 1997-04-18 Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren Withdrawn DE19716154A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE19716154A DE19716154A1 (de) 1997-04-18 1997-04-18 Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren
BR9809103-4A BR9809103A (pt) 1997-04-18 1998-04-11 Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos
CA002288649A CA2288649A1 (en) 1997-04-18 1998-04-11 Stable pharmaceutical administration forms of peptides, proteins and nucleic acids
KR1019997009652A KR20010006562A (ko) 1997-04-18 1998-04-11 펩티드, 단백질 및 핵산의 안정한 약학 투여 형태물
PCT/EP1998/002131 WO1998047490A1 (de) 1997-04-18 1998-04-11 Stabile pharmazeutische darreichungsform für peptide, proteine und nukleinsäuren
JP54494698A JP2001524090A (ja) 1997-04-18 1998-04-11 ペプチド、タンパク質および核酸を投与するための安定製剤形態
CN98806448A CN1261271A (zh) 1997-04-18 1998-04-11 多肽、蛋白和核酸的稳定的药用施用形式
TR1999/02575T TR199902575T2 (xx) 1997-04-18 1998-04-11 Peptitler, proteinler ve nükleik asitler için stabil farmasötik uygulama formu.
AU77585/98A AU744777B2 (en) 1997-04-18 1998-04-11 Stable pharmaceutical administration forms of peptides, proteins and nucleic acids
EP98925470A EP0975335A1 (de) 1997-04-18 1998-04-11 Stabile pharmazeutische darreichungsform für peptide, proteine und nukleinsäuren
US10/046,311 US20020103126A1 (en) 1997-04-18 2002-01-16 Stable pharmaceutical form of administration for peptides, proteins and nucleic acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19716154A DE19716154A1 (de) 1997-04-18 1997-04-18 Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren

Publications (1)

Publication Number Publication Date
DE19716154A1 true DE19716154A1 (de) 1998-10-22

Family

ID=7826847

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19716154A Withdrawn DE19716154A1 (de) 1997-04-18 1997-04-18 Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren

Country Status (10)

Country Link
EP (1) EP0975335A1 (ja)
JP (1) JP2001524090A (ja)
KR (1) KR20010006562A (ja)
CN (1) CN1261271A (ja)
AU (1) AU744777B2 (ja)
BR (1) BR9809103A (ja)
CA (1) CA2288649A1 (ja)
DE (1) DE19716154A1 (ja)
TR (1) TR199902575T2 (ja)
WO (1) WO1998047490A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012756A2 (de) * 1998-08-28 2000-03-09 Thomas Koehler Mit nukleinsäuren beschichtete reaktionsräume, verfahren zu ihrer herstellung und ihre verwendung
WO2003030866A1 (de) * 2001-10-05 2003-04-17 Viscum Ag Stabile galenische gefriergetrocknete arzneimittelzubereitung von rekombinanten carbohydratbindenden polypeptiden
WO2005116081A2 (en) * 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
WO2009086166A1 (en) * 2007-12-19 2009-07-09 Ekr Therapeutics, Inc. Room temperature stable, lyophilized natriuretic peptide formulations
US8283165B2 (en) 2008-09-12 2012-10-09 Genvault Corporation Matrices and media for storage and stabilization of biomolecules

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1555033A3 (en) * 1998-03-13 2005-08-17 Wyeth Polynucleotide composition, method of preparation, and use thereof
DE69925113T2 (de) * 1998-03-13 2006-01-19 Wyeth Polynukleotidzusammensetzung, verfahren zu deren herstellung und verwendung
US7276359B1 (en) 1998-03-13 2007-10-02 Wyeth Polynucleotide composition, method of preparation, and use thereof
DE60034445T2 (de) * 1999-05-31 2008-01-03 Mitsubishi Chemical Corp. Gefriergetrocknete hgf-präparationen
EP1651275A1 (en) * 2003-08-05 2006-05-03 Fuji Photo Film B.V. Use of recombinant or synthetic gelatin-like proteins as stabiliser in lyophilized pharmaceutical compositions
GB0517688D0 (en) * 2005-08-31 2005-10-05 Cambridge Biostability Ltd Improvements in the stabilisation of biological materials
JP2016109911A (ja) 2014-12-08 2016-06-20 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． 表示装置、表示方法、及びプログラム
JP2016109914A (ja) 2014-12-08 2016-06-20 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． 表示装置、表示方法、及びプログラム
KR102369835B1 (ko) 2014-12-08 2022-03-04 삼성디스플레이 주식회사 표시 장치 및 표시 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63115822A (ja) * 1986-11-04 1988-05-20 Teijin Ltd 生理活性ポリペプチド類の経鼻投与用粉末状組成物
DE3729863A1 (de) * 1987-09-05 1989-03-16 Boehringer Mannheim Gmbh Stabilisierte erythropoietin-lyophilisate
DE4126983A1 (de) * 1991-08-15 1993-02-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke
DE4126984A1 (de) * 1991-08-15 1993-02-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von humanprotein-enthaltenden, gut vertraeglichen arzneimitteln fuer infusions- oder injektionszwecke
DE19538687A1 (de) * 1995-10-17 1997-04-24 Boehringer Mannheim Gmbh Stabile pharmazeutische Darreichungsformen enthaltend Parathormon

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012756A2 (de) * 1998-08-28 2000-03-09 Thomas Koehler Mit nukleinsäuren beschichtete reaktionsräume, verfahren zu ihrer herstellung und ihre verwendung
WO2000012756A3 (de) * 1998-08-28 2000-05-18 Thomas Koehler Mit nukleinsäuren beschichtete reaktionsräume, verfahren zu ihrer herstellung und ihre verwendung
WO2003030866A1 (de) * 2001-10-05 2003-04-17 Viscum Ag Stabile galenische gefriergetrocknete arzneimittelzubereitung von rekombinanten carbohydratbindenden polypeptiden
WO2005116081A2 (en) * 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
WO2005116081A3 (en) * 2004-05-24 2006-07-06 Genvault Corp Stable protein storage and stable nucleic acid storage in recoverable form
US8431384B2 (en) 2004-05-24 2013-04-30 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
WO2009086166A1 (en) * 2007-12-19 2009-07-09 Ekr Therapeutics, Inc. Room temperature stable, lyophilized natriuretic peptide formulations
US8283165B2 (en) 2008-09-12 2012-10-09 Genvault Corporation Matrices and media for storage and stabilization of biomolecules
US8951719B2 (en) 2008-09-12 2015-02-10 Gentegra, LLC. Matrices and media for storage and stabilization of biomolecules
US9637513B2 (en) 2008-09-12 2017-05-02 Gentegra Llc Matrices and media for storage and stabilization of biomolecules
US10160997B2 (en) 2008-09-12 2018-12-25 Gentegra Llc Matrices and media for storage and stabilization of biomolecules

Also Published As

Publication number Publication date
CN1261271A (zh) 2000-07-26
BR9809103A (pt) 2000-08-01
JP2001524090A (ja) 2001-11-27
TR199902575T2 (xx) 2000-02-21
KR20010006562A (ko) 2001-01-26
AU7758598A (en) 1998-11-13
AU744777B2 (en) 2002-03-07
WO1998047490A1 (de) 1998-10-29
EP0975335A1 (de) 2000-02-02
CA2288649A1 (en) 1998-10-29

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: ROCHE DIAGNOSTICS GMBH, 68305 MANNHEIM, DE

8141 Disposal/no request for examination