DE1950351C3 - l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel - Google Patents

l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Info

Publication number
DE1950351C3
DE1950351C3 DE19691950351 DE1950351A DE1950351C3 DE 1950351 C3 DE1950351 C3 DE 1950351C3 DE 19691950351 DE19691950351 DE 19691950351 DE 1950351 A DE1950351 A DE 1950351A DE 1950351 C3 DE1950351 C3 DE 1950351C3
Authority
DE
Germany
Prior art keywords
methylphenoxy
hydroxy
cyano
formula
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19691950351
Other languages
German (de)
English (en)
Other versions
DE1950351B2 (de
DE1950351A1 (de
Inventor
A Engelhardt
H Koppe
K Zeile
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BG018263A priority Critical patent/BG17528A3/xx
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Priority to DE19691950351 priority patent/DE1950351C3/de
Priority to BG015085A priority patent/BG17590A3/xx
Priority to CS646770A priority patent/CS162731B2/cs
Priority to BG018262A priority patent/BG17294A3/xx
Priority to CH546219D priority patent/CH546219A/xx
Priority to BG015776A priority patent/BG17293A3/xx
Priority to CH546221D priority patent/CH546221A/xx
Priority to CH697273A priority patent/CH553166A/xx
Priority to CH546220D priority patent/CH546220A/xx
Priority to BG018266A priority patent/BG17529A3/xx
Priority to CH1461770A priority patent/CH542814A/de
Priority to CH546222D priority patent/CH546222A/xx
Priority to BG018261A priority patent/BG17527A3/xx
Priority to CH546218D priority patent/CH546218A/xx
Priority to CH697773A priority patent/CH553167A/xx
Priority to BG018264A priority patent/BG17295A3/xx
Priority to BG018265A priority patent/BG17296A3/xx
Priority to CH697573A priority patent/CH542815A/de
Priority to CH696973A priority patent/CH555322A/xx
Priority to BG018268A priority patent/BG17531A3/xx
Priority to ES384244A priority patent/ES384244A1/es
Priority to SE1347570A priority patent/SE375094B/xx
Priority to SU1481523A priority patent/SU361563A1/ru
Priority to PL14378570A priority patent/PL84252B1/pl
Priority to SU1699774A priority patent/SU426360A3/ru
Priority to JP8675670A priority patent/JPS501262B1/ja
Priority to SU1705732A priority patent/SU423291A3/ru
Priority to PL17334370A priority patent/PL84637B1/pl
Priority to PL17334270A priority patent/PL84642B1/pl
Priority to SU1705074A priority patent/SU400081A1/ru
Priority to SU1705040A priority patent/SU400082A1/ru
Priority to SU1705733A priority patent/SU421182A3/ru
Priority to DK505570A priority patent/DK128237B/da
Priority to SU1705730A priority patent/SU417938A3/ru
Priority to SU1705731A priority patent/SU422137A3/ru
Priority to YU244470A priority patent/YU34516B/xx
Priority to AT1052871A priority patent/AT306698B/de
Priority to RO6461670A priority patent/RO56983A/ro
Priority to RO6727270A priority patent/RO58534A/ro
Priority to AT1052971A priority patent/AT306699B/de
Priority to AT1052571A priority patent/AT306695B/de
Priority to RO6727170A priority patent/RO59186A/ro
Priority to AT1052771A priority patent/AT306697B/de
Priority to AT900970A priority patent/AT302274B/de
Priority to AT1052471A priority patent/AT306694B/de
Priority to AT1053171A priority patent/AT306701B/de
Priority to RO6727070A priority patent/RO58533A/ro
Priority to RO6727370A priority patent/RO58548A/ro
Priority to AT1052371A priority patent/AT308072B/de
Priority to RO6726970A priority patent/RO59185A/ro
Priority to RO6728970A priority patent/RO58550A/ro
Priority to AT1052671A priority patent/AT306696B/de
Priority to RO6727470A priority patent/RO58549A/ro
Priority to AT1053071A priority patent/AT306700B/de
Priority to RO6726870A priority patent/RO58532A/ro
Publication of DE1950351A1 publication Critical patent/DE1950351A1/de
Priority to ES391135A priority patent/ES391135A1/es
Priority to ES391137A priority patent/ES391137A1/es
Priority to ES391138A priority patent/ES391138A1/es
Priority to ES391136A priority patent/ES391136A1/es
Priority to ES391141A priority patent/ES391141A1/es
Priority to ES391139A priority patent/ES391139A1/es
Priority to ES391140A priority patent/ES391140A1/es
Priority to ES391134A priority patent/ES391134A1/es
Priority to SU1699773A priority patent/SU503507A3/ru
Publication of DE1950351B2 publication Critical patent/DE1950351B2/de
Application granted granted Critical
Publication of DE1950351C3 publication Critical patent/DE1950351C3/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • E—FIXED CONSTRUCTIONS
    • E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
    • E05D—HINGES OR SUSPENSION DEVICES FOR DOORS, WINDOWS OR WINGS
    • E05D15/00—Suspension arrangements for wings
    • E05D15/40—Suspension arrangements for wings supported on arms movable in vertical planes
    • E05D15/44—Suspension arrangements for wings supported on arms movable in vertical planes with pivoted arms and vertically-sliding guides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19691950351 1969-08-05 1969-10-06 l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel Expired DE1950351C3 (de)

Priority Applications (65)

Application Number Priority Date Filing Date Title
BG018263A BG17528A3 (bg) 1969-10-06 1969-10-02 Метод за получаване на заместени алкиламинопропани
DE19691950351 DE1950351C3 (de) 1969-10-06 1969-10-06 l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
BG015085A BG17590A3 (bg) 1969-08-05 1970-07-02 Метод за получаване на нови пиримидинови производни
CS646770A CS162731B2 (nl) 1969-10-06 1970-09-23
BG018262A BG17294A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на нови 1-<2-циано-5-метилфенокси>-2-хидрокси- 3-алкиламинопропани
CH546219D CH546219A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
BG015776A BG17293A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на заместени алкиламинопропан
CH546221D CH546221A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
CH697273A CH553166A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
CH546220D CH546220A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
BG018266A BG17529A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на алкиламинопропани
CH1461770A CH542814A (de) 1969-10-06 1970-10-02 Verfahren zur Herstellung neuer 1-(2'-Cyano-5'-methyl-phenoxy)-2-hydroxy-3-alkylaminopropane
CH546222D CH546222A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
BG018261A BG17527A3 (bg) 1969-10-06 1970-10-02 Метод за получаванк на заместени алкиламинопрополи
CH546218D CH546218A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
CH697773A CH553167A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-sek.-alkylaminopropane.
BG018264A BG17295A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на заместени алкиламинопропани
BG018265A BG17296A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на заместени алкиламинопропани
CH697573A CH542815A (de) 1969-10-06 1970-10-02 Verfahren zur Herstellung neuer 1-(2'-Cyano-5'-methyl-phenoxy)-2-hydroxy-3-alkylaminopropane
CH696973A CH555322A (de) 1969-10-06 1970-10-02 Verfahren zur herstellung neuer 1-(2'-cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropane.
BG018268A BG17531A3 (bg) 1969-10-06 1970-10-02 Метод за получаване на алкиламинопропани
ES384244A ES384244A1 (es) 1969-10-06 1970-10-03 Procedimiento para la preparacion de 1 - (2-ciano -5- me- tilfenoxi) -2- hidroxi-3-alcohilo inferior - aminopropanos racemicos u opticamente activos y sus sales por adicion de acido.
SE1347570A SE375094B (nl) 1969-10-06 1970-10-05
SU1481523A SU361563A1 (ru) 1970-10-05 Способ получения 1-
PL14378570A PL84252B1 (en) 1969-10-06 1970-10-05 (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia [DE1950351A1]
SU1699774A SU426360A3 (ru) 1969-10-06 1970-10-05 Способ получения 1-
JP8675670A JPS501262B1 (nl) 1969-10-06 1970-10-05
SU1705732A SU423291A3 (nl) 1969-10-06 1970-10-05
PL17334370A PL84637B1 (en) 1969-10-06 1970-10-05 (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia [DE1950351A1]
PL17334270A PL84642B1 (en) 1969-10-06 1970-10-05 (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia [DE1950351A1]
SU1705074A SU400081A1 (ru) 1970-10-05 Способ получения оптически активного
SU1705040A SU400082A1 (ru) 1970-10-05 В птб
SU1705733A SU421182A3 (ru) 1969-10-06 1970-10-05 Способ получения 1-
DK505570A DK128237B (da) 1969-10-06 1970-10-05 Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive N-alkyl-substituerede (2-cyano-5-methylphenoxy)-propanolaminer eller fysiologisk acceptable syreadditionssalte deraf.
SU1705730A SU417938A3 (ru) 1969-10-06 1970-10-05 Способ получения 1-
SU1705731A SU422137A3 (ru) 1969-10-06 1970-10-05 Способ получения 1-
YU244470A YU34516B (en) 1969-10-06 1970-10-05 Process for preparing novel 1-(2-cyano-5-methylphenoxy)-2-hydroxy-3-alkylamino propanes
AT1052871A AT306698B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen, sowie von deren Säureadditionssalzen
RO6461670A RO56983A (nl) 1969-10-06 1970-10-06
RO6727270A RO58534A (nl) 1969-10-06 1970-10-06
AT1052971A AT306699B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen, sowie von deren Säureadditionssalzen
AT1052571A AT306695B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkyl-aminopropanen, sowie von deren Säureadditionssalzen
RO6727170A RO59186A (nl) 1969-10-06 1970-10-06
AT1052771A AT306697B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen, sowie von deren Säureadditionssalzen
AT900970A AT302274B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen sowie deren Säureadditionssalzen
AT1052471A AT306694B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkyl-aminopropanen, sowie von deren Säureadditionssalzen
AT1053171A AT306701B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-sek. alkylaminopropanen, sowie von deren Säureadditionssalzen
RO6727070A RO58533A (nl) 1969-10-06 1970-10-06
RO6727370A RO58548A (nl) 1969-10-06 1970-10-06
AT1052371A AT308072B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen
RO6726970A RO59185A (nl) 1969-10-06 1970-10-06
RO6728970A RO58550A (nl) 1969-10-06 1970-10-06
AT1052671A AT306696B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen, sowie von deren Säureadditionssalzen
RO6727470A RO58549A (nl) 1969-10-06 1970-10-06
AT1053071A AT306700B (de) 1969-10-06 1970-10-06 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-(2'-Cyano-5'-methylphenoxy)-2-hydroxy-3-alkylaminopropanen, sowie von deren Säureadditionssalzen
RO6726870A RO58532A (nl) 1969-10-06 1970-10-06
ES391135A ES391135A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de acido.
ES391137A ES391137A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noix) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de aci- do.
ES391138A ES391138A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de aci- do.
ES391136A ES391136A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de aci- do.
ES391141A ES391141A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos racemicos u opticamente activos y sus sales por adicion de acido.
ES391139A ES391139A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de aci- do.
ES391140A ES391140A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metil-fe-noxi) - 2 - hidroxi-3-alcohilo inferior-aminopropanos race- micos u opticamente activos y sus sales por adicion de aci- do.
ES391134A ES391134A1 (es) 1969-10-06 1971-05-13 Procedimiento para la preparacion de 1-(2-ciano-5-metilfe- nixi) - 2 - hidroxi-3-alcohiloinferior-aminopropanosrecemi- cos u opticamente activos y sus sales por adicion de acido.
SU1699773A SU503507A3 (ru) 1969-10-06 1971-09-21 Способ получени 1-(2-циано-5-метилфенокси)-2-окси-3-алкиламинопропанов

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691950351 DE1950351C3 (de) 1969-10-06 1969-10-06 l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
DE1950351A1 DE1950351A1 (de) 1971-04-29
DE1950351B2 DE1950351B2 (de) 1978-04-27
DE1950351C3 true DE1950351C3 (de) 1978-12-21

Family

ID=5747463

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691950351 Expired DE1950351C3 (de) 1969-08-05 1969-10-06 l-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-aIkylaminopropane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Country Status (13)

Country Link
JP (1) JPS501262B1 (nl)
AT (10) AT306700B (nl)
BG (8) BG17528A3 (nl)
CH (1) CH542814A (nl)
CS (1) CS162731B2 (nl)
DE (1) DE1950351C3 (nl)
DK (1) DK128237B (nl)
ES (9) ES384244A1 (nl)
PL (3) PL84252B1 (nl)
RO (9) RO58534A (nl)
SE (1) SE375094B (nl)
SU (6) SU421182A3 (nl)
YU (1) YU34516B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101950B (fi) 1996-12-12 1998-09-30 Uponor Innovation Ab Menetelmä ja laitteisto kierrätettävän muovimateriaalin hyödyntämiseks i ja puristinlaitteella tehty muovituote
RU2660811C1 (ru) * 2017-03-21 2018-07-10 Общество с ограниченной ответственностью Научно-производственное предприятие "Резонанс" (ООО НПП "Резонанс") Индукторная электрическая машина

Also Published As

Publication number Publication date
SU361563A3 (nl) 1972-12-07
ES391134A1 (es) 1973-07-16
PL84642B1 (en) 1976-04-30
ES391141A1 (es) 1973-07-16
BG17296A3 (bg) 1973-07-25
PL84637B1 (en) 1976-04-30
BG17295A3 (bg) 1973-07-25
AT306698B (de) 1973-04-25
SU503507A3 (ru) 1976-02-15
ES384244A1 (es) 1973-01-01
BG17293A3 (bg) 1973-07-25
SE375094B (nl) 1975-04-07
SU422137A3 (ru) 1974-03-30
ES391138A1 (es) 1973-07-16
AT306699B (de) 1973-04-25
YU244470A (en) 1979-02-28
BG17531A3 (bg) 1973-11-10
BG17528A3 (bg) 1973-11-10
RO58534A (nl) 1975-09-15
RO58532A (nl) 1975-09-15
YU34516B (en) 1979-09-10
AT308072B (de) 1973-06-25
BG17527A3 (bg) 1973-11-10
AT306696B (de) 1973-04-25
DE1950351B2 (de) 1978-04-27
RO58548A (nl) 1975-09-15
RO59185A (nl) 1976-01-15
AT306697B (de) 1973-04-25
ES391137A1 (es) 1973-07-16
SU400082A3 (nl) 1973-10-03
SU400081A3 (nl) 1973-10-03
AT306700B (de) 1973-04-25
JPS501262B1 (nl) 1975-01-16
AT302274B (de) 1972-10-10
DE1950351A1 (de) 1971-04-29
AT306701B (de) 1973-04-25
AT306694B (de) 1973-04-25
SU417938A3 (ru) 1974-02-28
SU423291A3 (nl) 1974-04-05
BG17294A3 (bg) 1973-07-25
CH542814A (de) 1973-10-15
CS162731B2 (nl) 1975-07-15
DK128237B (da) 1974-03-25
ES391139A1 (es) 1973-07-16
RO58533A (nl) 1975-08-15
BG17529A3 (bg) 1973-11-10
SU426360A3 (ru) 1974-04-30
ES391135A1 (es) 1973-07-16
SU421182A3 (ru) 1974-03-25
RO59186A (nl) 1976-01-15
RO56983A (nl) 1974-12-15
ES391140A1 (es) 1973-07-16
PL84252B1 (en) 1976-03-31
RO58549A (nl) 1975-08-15
ES391136A1 (es) 1973-07-16
RO58550A (nl) 1975-08-15
AT306695B (de) 1973-04-25

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