DE1915196A1 - Jodierte Anilinderivate und Verfahren zu ihrer Herstellung - Google Patents

Jodierte Anilinderivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE1915196A1
DE1915196A1 DE19691915196 DE1915196A DE1915196A1 DE 1915196 A1 DE1915196 A1 DE 1915196A1 DE 19691915196 DE19691915196 DE 19691915196 DE 1915196 A DE1915196 A DE 1915196A DE 1915196 A1 DE1915196 A1 DE 1915196A1
Authority
DE
Germany
Prior art keywords
formula
acid
compound
lower alkyl
tri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19691915196
Other languages
German (de)
English (en)
Inventor
Ackerman James Howard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DE1915196A1 publication Critical patent/DE1915196A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408—Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • C07D265/33—Two oxygen atoms, in positions 3 and 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
DE19691915196 1968-03-25 1969-03-25 Jodierte Anilinderivate und Verfahren zu ihrer Herstellung Pending DE1915196A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71558368A 1968-03-25 1968-03-25

Publications (1)

Publication Number Publication Date
DE1915196A1 true DE1915196A1 (de) 1969-11-20

Family

ID=24874658

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691915196 Pending DE1915196A1 (de) 1968-03-25 1969-03-25 Jodierte Anilinderivate und Verfahren zu ihrer Herstellung

Country Status (11)

Country Link
BE (1) BE730385A (https=)
BR (1) BR6907386D0 (https=)
CA (1) CA946846A (https=)
CH (1) CH504412A (https=)
DE (1) DE1915196A1 (https=)
FR (1) FR2004680A1 (https=)
GB (1) GB1228521A (https=)
IL (1) IL31862A (https=)
IT (1) IT974525B (https=)
NL (1) NL6904602A (https=)
NO (1) NO124252B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0391847A1 (de) * 1989-04-04 1990-10-10 Ciba-Geigy Ag 1-Phenyl-piperidin-2,4-dione mit herbizider Wirkung

Also Published As

Publication number Publication date
GB1228521A (https=) 1971-04-15
CA946846A (en) 1974-05-07
IL31862A (en) 1973-08-29
NO124252B (https=) 1972-03-27
IT974525B (it) 1974-07-10
FR2004680A1 (https=) 1969-11-28
IL31862A0 (en) 1969-05-28
CH504412A (fr) 1971-03-15
BR6907386D0 (pt) 1973-05-31
BE730385A (https=) 1969-09-25
NL6904602A (https=) 1969-09-29

Similar Documents

Publication Publication Date Title
DE69119329T2 (de) Actinonin-Derivate
DE2419970C3 (de) 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung
DE2559866C2 (de) 2,4,6-Trijodbenzoesäure-Derivate und ihre Verwendung als Kontrastmittel für Röntgenaufnahmen
DE2461802C2 (de) Pyrazincarboxamidderivate
DE2225149C2 (de) Oxofurylesterderivate der 6-(ą-Aminophenylacetamido)penicillansäure, Verfahren zu deren Herstellung und ihre Verwendung
DE2446100C3 (de) Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel
DE1915196A1 (de) Jodierte Anilinderivate und Verfahren zu ihrer Herstellung
EP0032388B1 (de) Ionische 5-C-substituierte 2,4,6-trijod-isophthalsäure-Derivate, deren Herstellung und diese enthaltende Röntgenkontrastmittel
DE3145465C2 (https=)
DE2362535C2 (de) 2-Amino-1,2,3,4-tetrahydronaphthalin-und 3-Aminochromanol-(4)-Verbindungen und Verfahren zu deren Herstellung
US3290366A (en) 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives
DE2528795A1 (de) 2,4,6-trijod-5-methoxyacetamido- n-methylisophthalamische saeureverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende roentgenkontrastmittel
DE1443297C3 (de) 20.07.61 USA 125373 5-Amino-2,4,6-trijodisophthalamidsäurederivate Verfahren zu ihrer Herstellung und diese enthaltende Röntgenkontrastmittel Mallinckrodt Chemical Works, St. Louis, Mo. (V.St.A.)
DE2637665A1 (de) 5-substituierte 5h-dibenz(b,f)azepin- derivate und verfahren zu deren herstellung
US3359278A (en) Nu-substituted-2, 4, 6-triiodoanilic acids and salts thereof
DE69835742T2 (de) Herstellung von tri-iodo-benzol-verbindungen
CH533619A (de) Verfahren zur Herstellung von Pyrrolderivaten
DE2405652C3 (de) 3,6,9-Trioxaundecan-1,11 -dioyl-bis-(3-carboxy-2,4,6-trijod-anilid), dessen Salze mit physiologisch verträglichen Basen, Verfahren zur Herstellung dieser Verbindungen und diese Verbindungen enthaltende Röntgenkontrastmittel
DE3013545A1 (de) Heterocyclische thiomethylierung in der 3-position von 7-aminocephalosporansaeuren
AT343113B (de) Verfahren zur herstellung von neuen 5- oder 6- substituierten benzoxazolen
AT211296B (de) Verfahren zur Herstellung von neuen Sulfamylanthranilsäuren
DE2404924A1 (de) Ergolinderivate
DE2235915C3 (de) N-eckige Klammer auf 3-Pyrrolidinyliden-(2'-amino-2,4,6-trijodbenzoyl eckige Klammer zu - aminosäuren, deren Herstellung und Verwendung
AT376417B (de) Verfahren zur herstellung von phenylaethanolaminen und ihren salzen
AT360017B (de) Verfahren zur herstellung des neuen 1-methyl-4- (3-carboxy-10,11-dihydro-5h-dibenzo-(a,d)- -cyclohepten-5-yliden)-piperidin (10,11-dihydro -3-carboxy-cyproheptadin), seines n-oxids und seiner salze