DE1911581C3 - Cephalosporinderivate - Google Patents

Cephalosporinderivate

Info

Publication number
DE1911581C3
DE1911581C3 DE19691911581 DE1911581A DE1911581C3 DE 1911581 C3 DE1911581 C3 DE 1911581C3 DE 19691911581 DE19691911581 DE 19691911581 DE 1911581 A DE1911581 A DE 1911581A DE 1911581 C3 DE1911581 C3 DE 1911581C3
Authority
DE
Germany
Prior art keywords
acid
procedure
sodium
cephalosporin derivatives
acetoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19691911581
Other languages
German (de)
English (en)
Other versions
DE1911581A1 (de
DE1911581B2 (de
Inventor
Kenneth Butler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Publication of DE1911581A1 publication Critical patent/DE1911581A1/de
Publication of DE1911581B2 publication Critical patent/DE1911581B2/de
Application granted granted Critical
Publication of DE1911581C3 publication Critical patent/DE1911581C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19691911581 1968-03-27 1969-03-07 Cephalosporinderivate Expired DE1911581C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71630568A 1968-03-27 1968-03-27

Publications (3)

Publication Number Publication Date
DE1911581A1 DE1911581A1 (de) 1969-11-06
DE1911581B2 DE1911581B2 (de) 1972-11-30
DE1911581C3 true DE1911581C3 (de) 1973-06-28

Family

ID=24877514

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691911581 Expired DE1911581C3 (de) 1968-03-27 1969-03-07 Cephalosporinderivate

Country Status (8)

Country Link
US (1) US3635961A (https=)
JP (1) JPS4925274B1 (https=)
BE (1) BE729514A (https=)
BR (1) BR6907491D0 (https=)
CH (1) CH498866A (https=)
DE (1) DE1911581C3 (https=)
FR (1) FR2004804B1 (https=)
GB (1) GB1243206A (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651050A (en) * 1969-01-23 1972-03-21 Pfizer Acylation of 6-aminopenicillanic acid and 7-aminocephalosporanic acid
US4000133A (en) * 1973-06-06 1976-12-28 Fujisawa Pharmaceutical Co., Ltd. Substituted 7-styryl-carbonyloxy-acetamido cephalosporanic
US3993758A (en) * 1974-01-18 1976-11-23 Beecham Group Limited Cephalosporin compounds
US4160086A (en) * 1974-04-27 1979-07-03 Beecham Group Limited 3-Heterocyclicthio-7-α-carboxy 2-aryl acetamido cephalosporanic acid
US3979384A (en) * 1975-03-20 1976-09-07 Merck & Co., Inc. C-3 Substituted cephalosporins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341532A (en) * 1967-02-15 1967-09-12 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
FR2004804B1 (https=) 1973-01-12
DE1911581A1 (de) 1969-11-06
BR6907491D0 (pt) 1973-03-13
BE729514A (https=) 1969-09-08
GB1243206A (en) 1971-08-18
FR2004804A1 (https=) 1969-12-05
DE1911581B2 (de) 1972-11-30
US3635961A (en) 1972-01-18
CH498866A (fr) 1970-11-15
JPS4925274B1 (https=) 1974-06-28

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
8339 Ceased/non-payment of the annual fee