DE1793789C3 - Verfahren zur Herstellung von einen Cysteinrest enthaltenden Peptiden - Google Patents

Verfahren zur Herstellung von einen Cysteinrest enthaltenden Peptiden

Info

Publication number
DE1793789C3
DE1793789C3 DE1793789A DE1793789A DE1793789C3 DE 1793789 C3 DE1793789 C3 DE 1793789C3 DE 1793789 A DE1793789 A DE 1793789A DE 1793789 A DE1793789 A DE 1793789A DE 1793789 C3 DE1793789 C3 DE 1793789C3
Authority
DE
Germany
Prior art keywords
cysteine
acetamidomethylcysteine
group
acid
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1793789A
Other languages
German (de)
English (en)
Other versions
DE1793789B2 (de
DE1793789A1 (de
Inventor
Ralph Franz Plains Hirschmann
John David Rahway Milkowski
Daniel Frank Plainfield Veber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1793789A1 publication Critical patent/DE1793789A1/de
Publication of DE1793789B2 publication Critical patent/DE1793789B2/de
Application granted granted Critical
Publication of DE1793789C3 publication Critical patent/DE1793789C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE1793789A 1967-08-07 1968-08-05 Verfahren zur Herstellung von einen Cysteinrest enthaltenden Peptiden Expired DE1793789C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65866567A 1967-08-07 1967-08-07

Publications (3)

Publication Number Publication Date
DE1793789A1 DE1793789A1 (de) 1975-01-16
DE1793789B2 DE1793789B2 (de) 1979-06-21
DE1793789C3 true DE1793789C3 (de) 1980-02-14

Family

ID=24642155

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1793789A Expired DE1793789C3 (de) 1967-08-07 1968-08-05 Verfahren zur Herstellung von einen Cysteinrest enthaltenden Peptiden

Country Status (7)

Country Link
US (1) US3560521A (enExample)
JP (1) JPS538687B1 (enExample)
CH (1) CH498088A (enExample)
DE (1) DE1793789C3 (enExample)
FR (1) FR1576147A (enExample)
GB (2) GB1225019A (enExample)
NL (1) NL166254C (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH517705A (de) * 1969-12-16 1972-01-15 Ciba Geigy Ag Verfahren zur Herstellung von Cystin-haltigen Peptiden
BE785933A (fr) * 1971-07-07 1973-01-08 Ciba Geigy Procede de preparation de peptides contenant de la cystine
US3929758A (en) * 1974-09-12 1975-12-30 Armour Pharma Cyclization of cysteine-containing peptides
US4111924A (en) * 1976-01-05 1978-09-05 Takeda Chemical Industries, Ltd. Method for removal of thiol-protecting groups
US4113877A (en) * 1977-09-16 1978-09-12 Merck & Co., Inc. Substituted 2-aminomethylphenyl sulfamates

Also Published As

Publication number Publication date
GB1225019A (en) 1971-03-17
DE1793119A1 (de) 1972-04-06
DE1793119B2 (de) 1976-12-02
NL166254C (nl) 1981-07-15
FR1576147A (enExample) 1969-07-25
US3560521A (en) 1971-02-02
JPS538687B1 (enExample) 1978-03-31
GB1225018A (en) 1971-03-17
CH498088A (de) 1970-10-31
DE1793789B2 (de) 1979-06-21
NL166254B (nl) 1981-02-16
DE1793789A1 (de) 1975-01-16
NL6810421A (enExample) 1969-02-11

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)