DE1768762A1 - Verfahren zur Herstellung von Thallium- und Organothalliumsalzen von Peptidcarbamaten und -thiocarbamaten - Google Patents
Verfahren zur Herstellung von Thallium- und Organothalliumsalzen von Peptidcarbamaten und -thiocarbamatenInfo
- Publication number
- DE1768762A1 DE1768762A1 DE19681768762 DE1768762A DE1768762A1 DE 1768762 A1 DE1768762 A1 DE 1768762A1 DE 19681768762 DE19681768762 DE 19681768762 DE 1768762 A DE1768762 A DE 1768762A DE 1768762 A1 DE1768762 A1 DE 1768762A1
- Authority
- DE
- Germany
- Prior art keywords
- acid
- organothallium
- thallium
- group
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims 19
- 150000003839 salts Chemical class 0.000 title claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 title claims 9
- BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 title claims 5
- 229910052716 thallium Inorganic materials 0.000 title claims 4
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 title claims 3
- 150000004657 carbamic acid derivatives Chemical class 0.000 title claims 2
- 238000002360 preparation method Methods 0.000 title claims 2
- 239000002253 acid Substances 0.000 claims 11
- 239000003153 chemical reaction reagent Substances 0.000 claims 9
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 6
- -1 N-carboxyamino acid anhydrides Chemical class 0.000 claims 5
- 239000012736 aqueous medium Substances 0.000 claims 4
- 239000002609 medium Substances 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 230000035484 reaction time Effects 0.000 claims 3
- ZLUSCZLCHQSJRU-UHFFFAOYSA-N thallium(1+) Chemical class [Tl+] ZLUSCZLCHQSJRU-UHFFFAOYSA-N 0.000 claims 3
- 150000008065 acid anhydrides Chemical class 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 150000004820 halides Chemical class 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims 2
- VZYDKJOUEPFKMW-UHFFFAOYSA-N 2,3-dihydroxybenzenesulfonic acid Chemical compound OC1=CC=CC(S(O)(=O)=O)=C1O VZYDKJOUEPFKMW-UHFFFAOYSA-N 0.000 claims 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 claims 1
- 241000711981 Sais Species 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 238000005267 amalgamation Methods 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- ZINJLDJMHCUBIP-UHFFFAOYSA-N ethametsulfuron-methyl Chemical compound CCOC1=NC(NC)=NC(NC(=O)NS(=O)(=O)C=2C(=CC=CC=2)C(=O)OC)=N1 ZINJLDJMHCUBIP-UHFFFAOYSA-N 0.000 claims 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940098779 methanesulfonic acid Drugs 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
- 150000003871 sulfonates Chemical class 0.000 claims 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 claims 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65023667A | 1967-06-30 | 1967-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1768762A1 true DE1768762A1 (de) | 1971-12-02 |
Family
ID=24608059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19681768762 Pending DE1768762A1 (de) | 1967-06-30 | 1968-06-27 | Verfahren zur Herstellung von Thallium- und Organothalliumsalzen von Peptidcarbamaten und -thiocarbamaten |
Country Status (6)
| Country | Link |
|---|---|
| BR (1) | BR6800205D0 (enrdf_load_stackoverflow) |
| CH (1) | CH508662A (enrdf_load_stackoverflow) |
| DE (1) | DE1768762A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1570328A (enrdf_load_stackoverflow) |
| GB (1) | GB1195776A (enrdf_load_stackoverflow) |
| NL (1) | NL6808554A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1186986B (de) * | 1958-09-19 | 1965-02-11 | Jacob Moench Fa | Verschluss fuer Taschen, Koffer od. dgl. |
| DE1199937B (de) * | 1960-07-08 | 1965-09-02 | Bengtsson Sigurd W | Zweiteiliger Verschluss aus Kunststoff fuer Taschen oder andere mit einem Deckel versehene Behaelter od. dgl. |
| WO1980000252A1 (en) * | 1978-07-18 | 1980-02-21 | Kabi Ab | Bradykinin-inhibiting tripeptide derivatives |
-
1968
- 1968-06-18 NL NL6808554A patent/NL6808554A/xx unknown
- 1968-06-25 CH CH939768A patent/CH508662A/de not_active IP Right Cessation
- 1968-06-27 DE DE19681768762 patent/DE1768762A1/de active Pending
- 1968-06-27 BR BR20020568A patent/BR6800205D0/pt unknown
- 1968-06-28 FR FR1570328D patent/FR1570328A/fr not_active Expired
- 1968-06-28 GB GB3094668A patent/GB1195776A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1186986B (de) * | 1958-09-19 | 1965-02-11 | Jacob Moench Fa | Verschluss fuer Taschen, Koffer od. dgl. |
| DE1199937B (de) * | 1960-07-08 | 1965-09-02 | Bengtsson Sigurd W | Zweiteiliger Verschluss aus Kunststoff fuer Taschen oder andere mit einem Deckel versehene Behaelter od. dgl. |
| WO1980000252A1 (en) * | 1978-07-18 | 1980-02-21 | Kabi Ab | Bradykinin-inhibiting tripeptide derivatives |
| AT387393B (de) * | 1978-07-18 | 1989-01-10 | Kabi Ab | Verfahren zur herstellung von neuen tripeptidderivaten |
Also Published As
| Publication number | Publication date |
|---|---|
| CH508662A (de) | 1971-06-15 |
| GB1195776A (en) | 1970-06-24 |
| NL6808554A (enrdf_load_stackoverflow) | 1968-12-31 |
| FR1570328A (enrdf_load_stackoverflow) | 1969-06-06 |
| BR6800205D0 (pt) | 1973-04-26 |
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