DE1768334C3 - Schwefelhaltige Bisphenole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel - Google Patents
Schwefelhaltige Bisphenole, Verfahren zu deren Herstellung und diese enthaltende ArzneimittelInfo
- Publication number
- DE1768334C3 DE1768334C3 DE19681768334 DE1768334A DE1768334C3 DE 1768334 C3 DE1768334 C3 DE 1768334C3 DE 19681768334 DE19681768334 DE 19681768334 DE 1768334 A DE1768334 A DE 1768334A DE 1768334 C3 DE1768334 C3 DE 1768334C3
- Authority
- DE
- Germany
- Prior art keywords
- ecm
- crystals
- production
- solution
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/36—Sulfur-, selenium-, or tellurium-containing compounds
- C08K5/37—Thiols
- C08K5/375—Thiols containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63765067A | 1967-05-11 | 1967-05-11 | |
US63764967A | 1967-05-11 | 1967-05-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
DE1768334A1 DE1768334A1 (de) | 1971-11-11 |
DE1768334B2 DE1768334B2 (de) | 1977-10-13 |
DE1768334C3 true DE1768334C3 (de) | 1978-06-01 |
Family
ID=27092902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19681768334 Expired DE1768334C3 (de) | 1967-05-11 | 1968-05-02 | Schwefelhaltige Bisphenole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
Country Status (3)
Country | Link |
---|---|
DE (1) | DE1768334C3 (US06811534-20041102-M00003.png) |
FR (2) | FR8063M (US06811534-20041102-M00003.png) |
GB (1) | GB1199871A (US06811534-20041102-M00003.png) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1421108A (en) * | 1973-09-07 | 1976-01-14 | Exxon Research Engineering Co | Sulphurised phenols |
IL69691A (en) * | 1982-09-23 | 1988-01-31 | Merck Frosst Canada Inc | Leukotriene antagonists,their preparation and pharmaceutical compositions containing them |
ATE22072T1 (de) * | 1982-09-30 | 1986-09-15 | Merck Frosst Canada Inc | Leukotrienantagonisten, deren herstellung und diese enthaltende zusammensetzungen. |
EP0152022B1 (de) * | 1984-02-03 | 1988-10-05 | Ciba-Geigy Ag | Di-(substituiertes hydroxyphenylthio)-alkane und -cycloalkane und sie enthaltende Stoffzusammensetzungen |
US4560799A (en) | 1984-02-03 | 1985-12-24 | Ciba-Geigy Corporation | Tri- and Tetra-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers and stabilized compositions |
US5401883A (en) * | 1987-01-20 | 1995-03-28 | Merrell Dow Pharmaceuticals Inc. | Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4'-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol) |
CA1339222C (en) * | 1987-01-20 | 1997-08-05 | Merrell Dow Pharmaceuticals Inc. | Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4'-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol) |
US4975467A (en) * | 1987-03-17 | 1990-12-04 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions |
US4900757A (en) * | 1988-12-08 | 1990-02-13 | Merrell Dow Pharmaceuticals Inc. | Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane |
US4954528A (en) * | 1988-12-08 | 1990-09-04 | Merrell Dow Pharmaceuticals Inc. | Hypocholesterolemic use of bis(3,5-di-tertiary-butly-4-hydroxyphenylthio)methane |
AU5965890A (en) * | 1989-07-14 | 1991-02-22 | Biodor U.S. Holding | New antiviral agents |
US4959392A (en) * | 1989-07-24 | 1990-09-25 | Merrell Dow Pharmaceuticals Inc. | Method of treating diabetes mellitus |
US5677291A (en) * | 1993-12-10 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols |
US5795876A (en) * | 1996-04-30 | 1998-08-18 | Hoechst Marion Rousssel, Inc. | Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2, 6-di-alkyl-4-silyl-phenols |
US6114572A (en) * | 1996-11-20 | 2000-09-05 | Hoechst Marion Roussel, Inc. | Substituted phenols and thiophenols useful as antioxidant agents |
AU2002300328B2 (en) * | 1997-05-14 | 2006-04-13 | Atherogenics, Inc | Compounds and methods for the inhibition of the expression of VCAM-1 |
US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
AU2006202461B2 (en) * | 1997-05-14 | 2009-12-03 | Atherogenics, Inc. | Compositions and methods for the inhibition of the expression of VCAM-1 |
WO1998051662A2 (en) * | 1997-05-14 | 1998-11-19 | Atherogenics, Inc. | Compounds and methods for the inhibition of the expression of vcam-1 |
EP1695959A1 (en) * | 1997-05-14 | 2006-08-30 | Atherogenics, Inc. | Compouds and methods for the inhibition of the expression of VCAM-1 |
US6852878B2 (en) | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
US6121463A (en) * | 1997-06-24 | 2000-09-19 | Hoechst Marion Roussel, Inc. | Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents |
US6133467A (en) * | 1997-06-25 | 2000-10-17 | Hoechst Marion Roussel, Inc. | 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxy-phenylsilyl)methyloxy]phenol |
US20070260087A1 (en) | 2004-04-20 | 2007-11-08 | Atherogenics, Inc. | Process of Preparing Esters and Ethers of Probucol and Derivatives Thereof |
WO2006063408A1 (en) * | 2004-12-17 | 2006-06-22 | Stocker Ronald O | Compositions and methods for treating cardiovascular disorders |
EP2139320A4 (en) | 2007-03-26 | 2010-09-08 | Salutria Pharmaceuticals Llc | METHODS AND COMPOSITIONS OF PROBUCOL DERIVATIVES FOR THE TREATMENT OF DIABETES |
-
1968
- 1968-05-01 GB GB20551/68A patent/GB1199871A/en not_active Expired
- 1968-05-02 DE DE19681768334 patent/DE1768334C3/de not_active Expired
- 1968-05-09 FR FR151151A patent/FR8063M/fr not_active Expired
- 1968-05-09 FR FR1561853D patent/FR1561853A/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR1561853A (US06811534-20041102-M00003.png) | 1969-03-28 |
DE1768334B2 (de) | 1977-10-13 |
GB1199871A (en) | 1970-07-22 |
FR8063M (US06811534-20041102-M00003.png) | 1970-07-06 |
DE1768334A1 (de) | 1971-11-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C3 | Grant after two publication steps (3rd publication) |