DE1768033A1 - Pharmazeutische Praeparate mit antagonistischer Wirkung gegenueber Adrenalin - Google Patents
Pharmazeutische Praeparate mit antagonistischer Wirkung gegenueber AdrenalinInfo
- Publication number
- DE1768033A1 DE1768033A1 DE19681768033 DE1768033A DE1768033A1 DE 1768033 A1 DE1768033 A1 DE 1768033A1 DE 19681768033 DE19681768033 DE 19681768033 DE 1768033 A DE1768033 A DE 1768033A DE 1768033 A1 DE1768033 A1 DE 1768033A1
- Authority
- DE
- Germany
- Prior art keywords
- acetyl
- carvacrol
- pharmaceutical preparations
- adrenaline
- effect against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 4
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 title description 12
- 230000003042 antagnostic effect Effects 0.000 title description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 6
- 230000002378 acidificating effect Effects 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 1
- 239000000047 product Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 241000700198 Cavia Species 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- OIQOAYVCKAHSEJ-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol;hexadecanoic acid;octadecanoic acid Chemical compound OCCOCC(OCCO)COCCO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O OIQOAYVCKAHSEJ-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691926011 DE1926011A1 (de) | 1968-03-22 | 1969-05-21 | Pharmazeutisches Praeparat mit antagonistischer Wirkung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR101148A FR6488M (enrdf_load_stackoverflow) | 1967-03-31 | 1967-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1768033A1 true DE1768033A1 (de) | 1971-02-11 |
Family
ID=8627982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19681768033 Pending DE1768033A1 (de) | 1967-03-31 | 1968-03-22 | Pharmazeutische Praeparate mit antagonistischer Wirkung gegenueber Adrenalin |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE712911A (enrdf_load_stackoverflow) |
| CH (1) | CH484048A (enrdf_load_stackoverflow) |
| DE (1) | DE1768033A1 (enrdf_load_stackoverflow) |
| FR (1) | FR6488M (enrdf_load_stackoverflow) |
| LU (1) | LU55790A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6804484A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2666507A1 (fr) * | 1990-09-07 | 1992-03-13 | Sarget Lab | Compositions pharmaceutiques pour l'administration topique de moxisylyte et de desacetyl moxisylyte et leurs utilisations en therapeutique. |
-
1967
- 1967-03-31 FR FR101148A patent/FR6488M/fr not_active Expired
-
1968
- 1968-03-22 DE DE19681768033 patent/DE1768033A1/de active Pending
- 1968-03-28 BE BE712911A patent/BE712911A/xx not_active IP Right Cessation
- 1968-03-29 NL NL6804484A patent/NL6804484A/xx unknown
- 1968-03-29 LU LU55790D patent/LU55790A1/xx unknown
- 1968-03-29 CH CH467468A patent/CH484048A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR6488M (enrdf_load_stackoverflow) | 1968-11-25 |
| CH484048A (fr) | 1970-01-15 |
| NL6804484A (enrdf_load_stackoverflow) | 1968-10-01 |
| LU55790A1 (enrdf_load_stackoverflow) | 1968-06-17 |
| BE712911A (enrdf_load_stackoverflow) | 1968-07-31 |
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