DE1445901A1 - Verfahren zur Herstellung von Benzodiazepinderivaten - Google Patents

Verfahren zur Herstellung von Benzodiazepinderivaten

Info

Publication number
DE1445901A1
DE1445901A1 DE19641445901 DE1445901A DE1445901A1 DE 1445901 A1 DE1445901 A1 DE 1445901A1 DE 19641445901 DE19641445901 DE 19641445901 DE 1445901 A DE1445901 A DE 1445901A DE 1445901 A1 DE1445901 A1 DE 1445901A1
Authority
DE
Germany
Prior art keywords
phenyl
dihydro
hydrogen
oxidation
benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19641445901
Other languages
German (de)
English (en)
Inventor
Sternbach Leo Henryk
Fryer Rodney Ian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE1445901A1 publication Critical patent/DE1445901A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19641445901 1963-07-10 1964-06-30 Verfahren zur Herstellung von Benzodiazepinderivaten Pending DE1445901A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US294142A US3247187A (en) 1963-07-10 1963-07-10 Oxidation of 1, 4-benzodiazepines to 1, 4-benzodiazepin-2-ones

Publications (1)

Publication Number Publication Date
DE1445901A1 true DE1445901A1 (de) 1969-02-06

Family

ID=23132071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19641445901 Pending DE1445901A1 (de) 1963-07-10 1964-06-30 Verfahren zur Herstellung von Benzodiazepinderivaten

Country Status (11)

Country Link
US (1) US3247187A (enExample)
BE (1) BE650261A (enExample)
BR (1) BR6460685D0 (enExample)
CH (1) CH458371A (enExample)
DE (1) DE1445901A1 (enExample)
DK (1) DK120600B (enExample)
ES (1) ES301865A1 (enExample)
GB (1) GB1036577A (enExample)
NL (1) NL6407796A (enExample)
NO (1) NO117639B (enExample)
OA (1) OA00949A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361742A (en) * 1964-12-07 1968-01-02 Hoffmann La Roche 5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
US3405123A (en) * 1965-02-08 1968-10-08 Hoffmann La Roche Process for preparing 1, 4-benzodiazepin-2-ones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176009A (en) * 1965-03-30 Hydrolysis of l-acylated-j-acyloxy benzodiazepines
US3121076A (en) * 1964-02-11 Benzodiazepinones and processes

Also Published As

Publication number Publication date
DK120600B (da) 1971-06-21
US3247187A (en) 1966-04-19
NO117639B (enExample) 1969-09-08
BR6460685D0 (pt) 1973-07-19
GB1036577A (en) 1966-07-20
CH458371A (de) 1968-06-30
OA00949A (fr) 1968-03-22
BE650261A (enExample) 1965-01-08
ES301865A1 (es) 1965-02-01
NL6407796A (enExample) 1965-01-11

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