DE122007000033I1 - Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln - Google Patents

Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln

Info

Publication number
DE122007000033I1
DE122007000033I1 DE200712000033 DE122007000033C DE122007000033I1 DE 122007000033 I1 DE122007000033 I1 DE 122007000033I1 DE 200712000033 DE200712000033 DE 200712000033 DE 122007000033 C DE122007000033 C DE 122007000033C DE 122007000033 I1 DE122007000033 I1 DE 122007000033I1
Authority
DE
Germany
Prior art keywords
disassembled
particles
producing
human papillomavirus
papillomavirus vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE200712000033
Other languages
German (de)
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26824774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122007000033(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE122007000033I1 publication Critical patent/DE122007000033I1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE200712000033 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln Pending DE122007000033I1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12652899P 1999-03-26 1999-03-26
US09/524,624 US6245568B1 (en) 1999-03-26 2000-03-13 Human papilloma virus vaccine with disassembled and reassembled virus-like particles
PCT/US2000/007595 WO2000057906A1 (en) 1999-03-26 2000-03-22 Human papillomavirus vaccine with disassembled and reassembled virus-like particles

Publications (1)

Publication Number Publication Date
DE122007000033I1 true DE122007000033I1 (de) 2007-08-09

Family

ID=26824774

Family Applications (4)

Application Number Title Priority Date Filing Date
DE200712000033 Pending DE122007000033I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln
DE60030698T Expired - Lifetime DE60030698T2 (de) 1999-03-26 2000-03-22 Verfahren zur herstellung eines human-papillomavirus-vakzins mit disassemblierten und reassemblierten virus-aehnlichen partikeln
DE200712000032 Pending DE122007000032I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und Reassembliertenn Virusaehnlichen Partikeln
DE200712000034 Pending DE122007000034I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln

Family Applications After (3)

Application Number Title Priority Date Filing Date
DE60030698T Expired - Lifetime DE60030698T2 (de) 1999-03-26 2000-03-22 Verfahren zur herstellung eines human-papillomavirus-vakzins mit disassemblierten und reassemblierten virus-aehnlichen partikeln
DE200712000032 Pending DE122007000032I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und Reassembliertenn Virusaehnlichen Partikeln
DE200712000034 Pending DE122007000034I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln

Country Status (19)

Country Link
US (2) US6245568B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP1165126B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP4594534B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR20020013516A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR023166A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE339222T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU778937B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2368391C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (4) CY1105779T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (4) DE122007000033I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1165126T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2270822T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR07C0026I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LT (1) LTC1165126I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (3) LU91328I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (3) NL300268I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT1165126E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI1165126T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2000057906A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US6962777B1 (en) * 1997-09-05 2005-11-08 Medimmune, Inc. In vitro method for disassembly/reassembly of papillomavirus virus-like particles (vlps), homogeneous vlp and capsomere compositions produced by said methods; use thereof as vehicle for improved purification, and delivery of active agents
WO2001042780A1 (en) * 1999-12-09 2001-06-14 Medimmune, Inc. IN VITRO METHOD FOR DISASSEMBLY/REASSEMBLY OF PAPILLOMAVIRUS VIRUS-LIKE PARTICLES (VLPs)
CN100350972C (zh) * 2001-07-26 2007-11-28 启龙股份公司 含有铝佐剂和组氨酸的疫苗
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US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
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AU2003213060A1 (en) * 2002-02-14 2003-09-04 Novavax, Inc. Optimization of gene sequences of chimeric virus-like particles for expression in insect cells
GB0206359D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
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DE10237639A1 (de) * 2002-08-13 2004-02-26 Martin-Luther-Universität Halle-Wittenberg Verfahren zur Herstellung von virusanalogen Partikeln durch in vitro-Assemblierung von Kapsomeren oder von Kapsomeren, an die biologisch aktive Makromoleküle gebunden sind, bei gleichzeitiger Verpackung der Makromoleküle
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
AU2003287980B2 (en) 2002-11-01 2009-06-25 Glaxosmithkline Biologicals S.A. Drying process
DE60336581D1 (de) 2002-12-20 2011-05-12 Glaxosmithkline Biolog Sa Verwendung von HPV16 und HPV18 VLPs als Vakzine gegen eine oder mehrere onkogene HPV des Typus 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
US7858098B2 (en) * 2002-12-20 2010-12-28 Glaxosmithkline Biologicals, S.A. Vaccine
EP1785433A4 (en) * 2004-07-01 2008-10-01 Tokyo Inst Tech VIRAL PARTICLE-LIKE CONSTRUCTION AND PROCESS FOR FORMING THE SAME IN PHYSIOLOGICAL CONDITIONS
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CN101460636A (zh) * 2006-05-11 2009-06-17 伯克顿迪金森公司 从细胞中提取蛋白质的方法
US9207240B2 (en) 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
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FI3831406T3 (fi) 2010-08-23 2024-08-06 Wyeth Llc Neisseria meningitidis rlp2086 -antigeenien stabiileja formulaatioita
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KR101559622B1 (ko) * 2012-07-30 2015-10-13 중앙대학교 산학협력단 인유두종바이러스 바이러스 유사입자의 고효율 정제방법
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CN118021947A (zh) 2017-01-31 2024-05-14 辉瑞大药厂 脑膜炎奈瑟菌组合物及其使用方法
WO2018152505A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Efficient cell free production of papillomavirus gene transfer vectors
KR102651043B1 (ko) 2017-10-30 2024-03-22 다케다 야쿠힌 고교 가부시키가이샤 지질-외피보유 바이러스의 불활성화를 위한 환경 친화적 세제
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Also Published As

Publication number Publication date
FR07C0026I2 (fr) 2012-08-03
DE60030698T2 (de) 2007-07-19
CY2007008I1 (el) 2009-11-04
CA2368391A1 (en) 2000-10-05
DE122007000032I1 (de) 2007-08-09
LU91328I9 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2019-03-01
LTPA2007002I1 (lt) 2020-03-25
CY2007010I1 (el) 2009-11-04
AU3909300A (en) 2000-10-16
LU91326I9 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2018-12-31
CA2368391C (en) 2011-06-07
JP4594534B2 (ja) 2010-12-08
NL300268I1 (nl) 2007-05-01
CY2007009I1 (el) 2010-07-28
EP1165126A1 (en) 2002-01-02
NL300270I1 (nl) 2007-05-01
ES2270822T3 (es) 2007-04-16
JP2002540167A (ja) 2002-11-26
PT1165126E (pt) 2006-12-29
CY2007010I2 (el) 2009-11-04
AR023166A1 (es) 2002-09-04
US20010021385A1 (en) 2001-09-13
DK1165126T3 (da) 2007-01-08
NL300269I1 (nl) 2007-05-01
DE122007000034I1 (de) 2007-08-09
FR07C0026I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2007-04-27
ATE339222T1 (de) 2006-10-15
DE60030698D1 (de) 2006-10-26
NL300269I2 (nl) 2008-07-01
AU778937B2 (en) 2004-12-23
LU91327I2 (fr) 2007-05-14
WO2000057906A1 (en) 2000-10-05
LU91327I9 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2019-03-01
CY2007009I2 (el) 2010-07-28
LU91328I2 (fr) 2007-05-14
CY1105779T1 (el) 2010-07-28
LTC1165126I2 (lt) 2020-04-27
SI1165126T1 (sl) 2006-12-31
LU91326I2 (fr) 2007-05-14
KR20020013516A (ko) 2002-02-20
EP1165126B1 (en) 2006-09-13
CY2007008I2 (el) 2009-11-04
US6245568B1 (en) 2001-06-12

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