DE10013732A1 - Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems - Google Patents
Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-SystemsInfo
- Publication number
- DE10013732A1 DE10013732A1 DE10013732A DE10013732A DE10013732A1 DE 10013732 A1 DE10013732 A1 DE 10013732A1 DE 10013732 A DE10013732 A DE 10013732A DE 10013732 A DE10013732 A DE 10013732A DE 10013732 A1 DE10013732 A1 DE 10013732A1
- Authority
- DE
- Germany
- Prior art keywords
- kcnq5
- protein
- polynucleotide
- kcnq3
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 101000994656 Homo sapiens Potassium voltage-gated channel subfamily KQT member 5 Proteins 0.000 title claims abstract description 86
- 102100034365 Potassium voltage-gated channel subfamily KQT member 5 Human genes 0.000 title claims abstract description 85
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- WPSYTTKBGAZSCX-UHFFFAOYSA-N Clofilium Chemical compound CCCCCCC[N+](CC)(CC)CCCCC1=CC=C(Cl)C=C1 WPSYTTKBGAZSCX-UHFFFAOYSA-N 0.000 description 3
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- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 description 1
- UPJKSWLLCONYMW-UHFFFAOYSA-N 5'-Adenosine monophosphate Natural products COc1cc(O)c(C(=O)C)c(OC2OC(COC3OC(C)C(O)C(O)C3O)C(O)C(O)C2O)c1 UPJKSWLLCONYMW-UHFFFAOYSA-N 0.000 description 1
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- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10013732A DE10013732A1 (de) | 2000-03-21 | 2000-03-21 | Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems |
| AT01909831T ATE336508T1 (de) | 2000-03-21 | 2001-03-13 | Kaliumkanalprotein kcnq5, ein ziel für erkrankungen des zentralen nervensystems und herz-gefäss-systems |
| DE60122301T DE60122301T2 (de) | 2000-03-21 | 2001-03-13 | Kaliumkanalprotein kcnq5, ein ziel für erkrankungen des zentralen nervensystems und herz-gefäss-systems |
| JP2001569011A JP5622345B2 (ja) | 2000-03-21 | 2001-03-13 | 中枢神経系疾患および心血管系疾患の標的であるカリウムチャネルタンパク質ｋｃｎｑ５ |
| EP01909831A EP1268545B1 (en) | 2000-03-21 | 2001-03-13 | Potassium channel protein kcnq5, a target for diseases of central nervous system and cardiovascular system |
| PCT/EP2001/002791 WO2001070811A1 (en) | 2000-03-21 | 2001-03-13 | Potassium channel protein kcnq5, a target for diseases of central nervous system and cardiovascular system |
| AU2001237438A AU2001237438A1 (en) | 2000-03-21 | 2001-03-13 | Potassium channel protein kcnq5, a target for diseases of central nervous systemand cardiovascular system |
| US09/813,148 US6617131B2 (en) | 2000-03-21 | 2001-03-21 | Nucleic acid molecule encoding the potassium channel protein, KCNQ5 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10013732A DE10013732A1 (de) | 2000-03-21 | 2000-03-21 | Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10013732A1 true DE10013732A1 (de) | 2001-09-27 |
Family
ID=7635606
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10013732A Withdrawn DE10013732A1 (de) | 2000-03-21 | 2000-03-21 | Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems |
| DE60122301T Expired - Lifetime DE60122301T2 (de) | 2000-03-21 | 2001-03-13 | Kaliumkanalprotein kcnq5, ein ziel für erkrankungen des zentralen nervensystems und herz-gefäss-systems |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60122301T Expired - Lifetime DE60122301T2 (de) | 2000-03-21 | 2001-03-13 | Kaliumkanalprotein kcnq5, ein ziel für erkrankungen des zentralen nervensystems und herz-gefäss-systems |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1268545B1 (https=) |
| JP (1) | JP5622345B2 (https=) |
| AT (1) | ATE336508T1 (https=) |
| AU (1) | AU2001237438A1 (https=) |
| DE (2) | DE10013732A1 (https=) |
| WO (1) | WO2001070811A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1173465A4 (en) * | 1999-04-14 | 2002-10-02 | Merck & Co Inc | INNOVATIVE HUMAN POTENTIAL-DEPENDENT CHANNELS |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6649371B1 (en) | 1999-06-11 | 2003-11-18 | Neurosearch A/S | Potassium channel KCNQ5 and sequences encoding the same |
| WO2001092526A1 (en) * | 2000-05-26 | 2001-12-06 | Bristol-Myers Squibb Company | Human kcnq5 potassium channel, methods and compositions thereof |
| DE10342022A1 (de) | 2003-09-11 | 2005-04-07 | Voith Paper Patent Gmbh | Aufwickelvorrichtung |
| WO2007084497A1 (en) * | 2006-01-19 | 2007-07-26 | Wyeth | A novel rat voltage-gated potassium channel |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999007832A1 (en) * | 1997-08-12 | 1999-02-18 | Bristol-Myers Squibb Company | Kcnq potassium channels and methods of modulating same |
| EP1037900A4 (en) * | 1997-10-24 | 2006-08-30 | Univ Utah Res Found | KNCQ2 AND KNCQ3, GENES OF THE POTASSIUM CHANNEL HAVING MUTATION IN BENIGN FAMILY NEONATAL CONVULSIONS (BFNC) AND OTHER EPILEPSIES |
| GB9726339D0 (en) * | 1997-12-13 | 1998-02-11 | Zeneca Ltd | Human-derived tissue-specific potassium channel |
| AU2092700A (en) * | 1999-01-26 | 2000-08-18 | Neurosearch A/S | Novel potassium channels and genes encoding these potassium channels |
| ATE346152T1 (de) * | 1999-04-14 | 2006-12-15 | Merck & Co Inc | Neuartige menschliche kalium-potentialabhängige kanäle |
| JP4833467B2 (ja) * | 1999-06-11 | 2011-12-07 | ニューロサーチ、アクティーゼルスカブ | 新規カリウムチャネル及び同カリウムチャネルをコードする遺伝子 |
-
2000
- 2000-03-21 DE DE10013732A patent/DE10013732A1/de not_active Withdrawn
-
2001
- 2001-03-13 AT AT01909831T patent/ATE336508T1/de not_active IP Right Cessation
- 2001-03-13 WO PCT/EP2001/002791 patent/WO2001070811A1/en not_active Ceased
- 2001-03-13 AU AU2001237438A patent/AU2001237438A1/en not_active Abandoned
- 2001-03-13 JP JP2001569011A patent/JP5622345B2/ja not_active Expired - Fee Related
- 2001-03-13 DE DE60122301T patent/DE60122301T2/de not_active Expired - Lifetime
- 2001-03-13 EP EP01909831A patent/EP1268545B1/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1173465A4 (en) * | 1999-04-14 | 2002-10-02 | Merck & Co Inc | INNOVATIVE HUMAN POTENTIAL-DEPENDENT CHANNELS |
Also Published As
| Publication number | Publication date |
|---|---|
| DE60122301T2 (de) | 2007-09-13 |
| EP1268545A1 (en) | 2003-01-02 |
| AU2001237438A1 (en) | 2001-10-03 |
| ATE336508T1 (de) | 2006-09-15 |
| EP1268545B1 (en) | 2006-08-16 |
| JP5622345B2 (ja) | 2014-11-12 |
| JP2004512009A (ja) | 2004-04-22 |
| DE60122301D1 (de) | 2006-09-28 |
| WO2001070811A1 (en) | 2001-09-27 |
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| 8127 | New person/name/address of the applicant |
Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, 65929 FRANKFURT, |
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| 8141 | Disposal/no request for examination |