DD300105A5 - Neue R(-)3-Quinuliclidinol - Derivate - Google Patents
Neue R(-)3-Quinuliclidinol - Derivate Download PDFInfo
- Publication number
- DD300105A5 DD300105A5 DD341777A DD34177790A DD300105A5 DD 300105 A5 DD300105 A5 DD 300105A5 DD 341777 A DD341777 A DD 341777A DD 34177790 A DD34177790 A DD 34177790A DD 300105 A5 DD300105 A5 DD 300105A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- phenyl
- oxo
- carboxylate
- octyl
- compounds
- Prior art date
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- 150000001875 compounds Chemical class 0.000 claims abstract description 79
- 238000000034 method Methods 0.000 claims abstract description 23
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 17
- -1 3-quinuclidinyl Chemical group 0.000 claims abstract description 13
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 11
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- 150000003839 salts Chemical class 0.000 claims description 9
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- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 claims 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8920929A IT1230881B (it) | 1989-06-20 | 1989-06-20 | Derivati del r(-) 3-chinuclidinolo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD300105A5 true DD300105A5 (de) | 1992-05-21 |
Family
ID=11174223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD341777A DD300105A5 (de) | 1989-06-20 | 1990-06-18 | Neue R(-)3-Quinuliclidinol - Derivate |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5164386A (pl) |
| EP (1) | EP0404737A3 (pl) |
| JP (1) | JPH0331279A (pl) |
| KR (1) | KR910000720A (pl) |
| AU (1) | AU634787B2 (pl) |
| CA (1) | CA2019251A1 (pl) |
| DD (1) | DD300105A5 (pl) |
| FI (1) | FI94131C (pl) |
| HU (1) | HUT54151A (pl) |
| IE (1) | IE902208A1 (pl) |
| IL (1) | IL94763A (pl) |
| IT (1) | IT1230881B (pl) |
| NO (1) | NO174053C (pl) |
| NZ (1) | NZ234157A (pl) |
| PL (1) | PL164218B1 (pl) |
| PT (1) | PT94408A (pl) |
| RU (1) | RU2034843C1 (pl) |
| YU (1) | YU47356B (pl) |
| ZA (1) | ZA904736B (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| AU7618991A (en) * | 1990-05-14 | 1991-11-14 | Syntex (U.S.A.) Inc. | Novel tricyclic compounds |
| US5202318A (en) * | 1990-05-14 | 1993-04-13 | Syntex (U.S.A.) Inc. | Tricyclic compounds acting at serotonin receptor subtypes |
| AU652407B2 (en) * | 1991-01-10 | 1994-08-25 | Pfizer Inc. | N-alkyl quinuclidinium salts as substance P antagonists |
| US5340826A (en) * | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
| US7214686B2 (en) * | 1997-06-30 | 2007-05-08 | Targacept, Inc. | Pharmaceutical compositions and methods for effecting dopamine release |
| EE05404B1 (et) | 2000-12-28 | 2011-04-15 | Almirall Prodesfarma Ag | Kinuklidiini derivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette nhtud respiratoorsete, kuseelundite v?i mao-soolte haiguste ravimiseks, ning seda sisaldav ravimkompositsioon |
| WO2014105655A1 (en) | 2012-12-24 | 2014-07-03 | Neurogastrx, Inc. | Methods for treating gi tract disorders |
| WO2015200369A1 (en) | 2014-06-24 | 2015-12-30 | Neurogastrx, Inc. | Prodrugs of metopimazine |
| KR102423577B1 (ko) | 2017-04-07 | 2022-07-21 | 삼성전자주식회사 | 가전기기 |
| US10836757B1 (en) | 2020-04-02 | 2020-11-17 | Neurogastrx, Inc. | Polymorphic forms of metopimazine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3290316A (en) * | 1962-08-03 | 1966-12-06 | Hoffmann La Roche | Alpha-3-pyridylmandelic acid and derivatives thereof |
| DE3429830A1 (de) * | 1983-08-26 | 1985-03-07 | Sandoz-Patent-GmbH, 7850 Lörrach | Automatische carbonsaeure- und sulfonsaeureester oder -amide |
| CA1307790C (en) * | 1987-08-04 | 1992-09-22 | Ian Anthony Cliffe | Ethers |
| IL87674A (en) * | 1987-09-08 | 1993-08-18 | Lilly Co Eli | Azabicycloalkyl esters and amides of heterocyclic acids, their preparation and pharmaceutical compositions containing them |
| US4921982A (en) * | 1988-07-21 | 1990-05-01 | Eli Lilly And Company | 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists |
| IT1231413B (it) * | 1987-09-23 | 1991-12-04 | Angeli Inst Spa | Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht |
| US4975437A (en) * | 1989-12-14 | 1990-12-04 | Marion Laboratories, Inc. | Isomers of 1-azabicyclo(2.2.2)oct-3-yl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-nitropyridine-3-carboxylate |
-
1989
- 1989-06-20 IT IT8920929A patent/IT1230881B/it active
-
1990
- 1990-06-18 IL IL9476390A patent/IL94763A/en not_active IP Right Cessation
- 1990-06-18 PL PL90285669A patent/PL164218B1/pl unknown
- 1990-06-18 DD DD341777A patent/DD300105A5/de unknown
- 1990-06-19 YU YU120290A patent/YU47356B/sh unknown
- 1990-06-19 KR KR1019900008991A patent/KR910000720A/ko not_active Application Discontinuation
- 1990-06-19 EP EP19900830281 patent/EP0404737A3/en not_active Withdrawn
- 1990-06-19 JP JP2161192A patent/JPH0331279A/ja active Pending
- 1990-06-19 IE IE220890A patent/IE902208A1/en unknown
- 1990-06-19 FI FI903077A patent/FI94131C/fi not_active IP Right Cessation
- 1990-06-19 NO NO902710A patent/NO174053C/no unknown
- 1990-06-19 PT PT94408A patent/PT94408A/pt not_active Application Discontinuation
- 1990-06-19 HU HU903908A patent/HUT54151A/hu unknown
- 1990-06-19 ZA ZA904736A patent/ZA904736B/xx unknown
- 1990-06-19 CA CA002019251A patent/CA2019251A1/en not_active Abandoned
- 1990-06-20 NZ NZ234157A patent/NZ234157A/xx unknown
- 1990-06-20 US US07/541,106 patent/US5164386A/en not_active Expired - Fee Related
- 1990-06-20 AU AU57649/90A patent/AU634787B2/en not_active Ceased
-
1992
- 1992-03-10 RU SU925011061A patent/RU2034843C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0331279A (ja) | 1991-02-12 |
| NO174053B (no) | 1993-11-29 |
| FI903077A0 (fi) | 1990-06-19 |
| NZ234157A (en) | 1992-09-25 |
| EP0404737A3 (en) | 1992-03-11 |
| ZA904736B (en) | 1992-02-26 |
| AU634787B2 (en) | 1993-03-04 |
| NO902710L (no) | 1990-12-21 |
| FI94131B (fi) | 1995-04-13 |
| US5164386A (en) | 1992-11-17 |
| PT94408A (pt) | 1991-02-08 |
| PL164218B1 (pl) | 1994-07-29 |
| RU2034843C1 (ru) | 1995-05-10 |
| IE902208L (en) | 1990-12-20 |
| IE902208A1 (en) | 1991-01-02 |
| IT8920929A0 (it) | 1989-06-20 |
| YU47356B (sh) | 1995-01-31 |
| IT1230881B (it) | 1991-11-08 |
| NO902710D0 (no) | 1990-06-19 |
| YU120290A (sh) | 1992-12-21 |
| HU903908D0 (en) | 1990-11-28 |
| PL285669A1 (en) | 1991-03-11 |
| IL94763A0 (en) | 1991-04-15 |
| IL94763A (en) | 1994-08-26 |
| EP0404737A2 (en) | 1990-12-27 |
| AU5764990A (en) | 1991-01-03 |
| NO174053C (no) | 1994-03-16 |
| FI94131C (fi) | 1995-07-25 |
| CA2019251A1 (en) | 1990-12-20 |
| HUT54151A (en) | 1991-01-28 |
| KR910000720A (ko) | 1991-01-30 |
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