DD298912A5 - Verfahren zur herstellung von 3-aminopyrrolen - Google Patents

Verfahren zur herstellung von 3-aminopyrrolen Download PDF

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Publication number
DD298912A5
DD298912A5 DD89334670A DD33467089A DD298912A5 DD 298912 A5 DD298912 A5 DD 298912A5 DD 89334670 A DD89334670 A DD 89334670A DD 33467089 A DD33467089 A DD 33467089A DD 298912 A5 DD298912 A5 DD 298912A5
Authority
DD
German Democratic Republic
Prior art keywords
odor
alkyl
substituted
dor
aryl
Prior art date
Application number
DD89334670A
Other languages
German (de)
English (en)
Inventor
Juergen Liebscher
Alexander Knoll
Alexej Uschmajew
Andreas Rolfs
Dieter Lohmann
Gottfried Faust
Eveline Morgenstern
Peter Scharfenberg
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@������������@��k�� filed Critical �������@������������@��k��
Priority to DD89334670A priority Critical patent/DD298912A5/de
Priority to SI9012173A priority patent/SI20323B/sl
Priority to YU217390A priority patent/YU48469B/sh
Priority to DE59010759T priority patent/DE59010759D1/de
Priority to JP2311258A priority patent/JPH07113015B2/ja
Priority to RU94002476A priority patent/RU2120796C1/ru
Priority to HU907176A priority patent/HUT56343A/hu
Priority to US07/614,459 priority patent/US5502051A/en
Priority to EP90121958A priority patent/EP0431371B1/fr
Priority to ES90121958T priority patent/ES2108005T3/es
Priority to SU904831894A priority patent/RU2060991C1/ru
Priority to FI905689A priority patent/FI102169B1/fi
Publication of DD298912A5 publication Critical patent/DD298912A5/de
Priority to HR930229A priority patent/HRP930229A2/xx
Priority to US08/446,000 priority patent/US5684160A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD89334670A 1989-11-17 1989-11-17 Verfahren zur herstellung von 3-aminopyrrolen DD298912A5 (de)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DD89334670A DD298912A5 (de) 1989-11-17 1989-11-17 Verfahren zur herstellung von 3-aminopyrrolen
SI9012173A SI20323B (en) 1989-11-17 1990-11-15 3-Aminopyrrole, process for preparation and its use as a pharmaceutical composition or medicine
YU217390A YU48469B (sh) 1989-11-17 1990-11-15 3-aminopiroli, postupak za njihovu izradu, kao i izrada farmaceutskih sastava koji ih sadrže 3-aminopirroles
US07/614,459 US5502051A (en) 1989-11-17 1990-11-16 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use
JP2311258A JPH07113015B2 (ja) 1989-11-17 1990-11-16 ３―アミノピロール、その製造方法およびその薬品または薬剤としての使用
RU94002476A RU2120796C1 (ru) 1989-11-17 1990-11-16 Фармацевтическая композиция, обладающая антиконвульсивной и анальгетической активностью
HU907176A HUT56343A (en) 1989-11-17 1990-11-16 Process for producing 3-aminopyrrol derivatives and pahrmaceutical compositions comprising same
DE59010759T DE59010759D1 (de) 1989-11-17 1990-11-16 3-Aminopyrrole, Verfahren zu ihrer Herstellung und ihre Verwendung als Antikonvulsiva
EP90121958A EP0431371B1 (fr) 1989-11-17 1990-11-16 3-Aminopyrroles, procédé pour leur préparation et leur utilisation comme anticonvulsifs
ES90121958T ES2108005T3 (es) 1989-11-17 1990-11-16 3-aminopirroles, procedimiento para su preparacion y su utilizacion como anti-convulsivos.
SU904831894A RU2060991C1 (ru) 1989-11-17 1990-11-16 3-аминопирролы и фармацевтическое средство, обладающее антиконвульсивным действием
FI905689A FI102169B1 (fi) 1989-11-17 1990-11-16 3-aminopyrrolit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina
HR930229A HRP930229A2 (en) 1989-11-17 1993-02-24 3-aminopyrroles, process for their preparation and their use as medicaments
US08/446,000 US5684160A (en) 1989-11-17 1995-05-19 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD89334670A DD298912A5 (de) 1989-11-17 1989-11-17 Verfahren zur herstellung von 3-aminopyrrolen

Publications (1)

Publication Number Publication Date
DD298912A5 true DD298912A5 (de) 1992-03-19

Family

ID=5613902

Family Applications (1)

Application Number Title Priority Date Filing Date
DD89334670A DD298912A5 (de) 1989-11-17 1989-11-17 Verfahren zur herstellung von 3-aminopyrrolen

Country Status (10)

Country Link
US (2) US5502051A (fr)
EP (1) EP0431371B1 (fr)
JP (1) JPH07113015B2 (fr)
DD (1) DD298912A5 (fr)
DE (1) DE59010759D1 (fr)
ES (1) ES2108005T3 (fr)
FI (1) FI102169B1 (fr)
HU (1) HUT56343A (fr)
RU (2) RU2120796C1 (fr)
YU (1) YU48469B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4227479A1 (de) * 1992-08-20 1994-02-24 Dresden Arzneimittel Verfahren zur Herstellung von 1-unsubstituierten 3-Aminopyrrolen
US5792778A (en) * 1995-08-10 1998-08-11 Merck & Co., Inc. 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
US5837719A (en) * 1995-08-10 1998-11-17 Merck & Co., Inc. 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
WO1997016441A1 (fr) * 1995-10-31 1997-05-09 Merck & Co., Inc. Pyrroles aryliques de substitution, compositions renfermant de telles composes et methodes d'utilisation de ces substances
US5908858A (en) 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
DE19629976A1 (de) * 1996-07-25 1998-01-29 Dresden Arzneimittel Verwendung von 4-(p-Halogenphenyl)-3-morpholinopyrrol-2-carbonsäuremethylester zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen
US5776954A (en) * 1996-10-30 1998-07-07 Merck & Co., Inc. Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
US7122666B2 (en) 1999-07-21 2006-10-17 Sankyo Company, Limited Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses
EP2170062A4 (fr) 2007-07-12 2010-12-29 Tragara Pharmaceuticals Inc Procédés et compositions pour le traitement du cancer, de tumeurs et de troubles liés à des tumeurs
US9944597B2 (en) 2013-09-16 2018-04-17 The Board Of Regents Of The University Of Texas System Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198502A (en) * 1973-08-22 1980-04-15 Gruppo Lepetit S.P.A. Aminopyrrole derivatives
US4748183A (en) * 1986-06-13 1988-05-31 Warner-Lambert Company N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof

Also Published As

Publication number Publication date
EP0431371B1 (fr) 1997-09-10
FI102169B (fi) 1998-10-30
FI102169B1 (fi) 1998-10-30
RU2120796C1 (ru) 1998-10-27
YU217390A (sh) 1993-05-28
US5684160A (en) 1997-11-04
RU2060991C1 (ru) 1996-05-27
FI905689A0 (fi) 1990-11-16
ES2108005T3 (es) 1997-12-16
JPH07113015B2 (ja) 1995-12-06
DE59010759D1 (de) 1997-10-16
EP0431371A1 (fr) 1991-06-12
US5502051A (en) 1996-03-26
JPH03271271A (ja) 1991-12-03
HUT56343A (en) 1991-08-28
HU907176D0 (en) 1991-05-28
YU48469B (sh) 1998-08-14
FI905689A (fi) 1991-05-18

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Legal Events

Date Code Title Description
RPV Change in the person, the name or the address of the representative (searches according to art. 11 and 12 extension act)

Free format text: PATENTANWAELTE WEICKMANN & WEICKMANN, 81679 MUENCHEN

ENJ Ceased due to non-payment of renewal fee