YU48469B - 3-aminopiroli, postupak za njihovu izradu, kao i izrada farmaceutskih sastava koji ih sadrže 3-aminopirroles - Google Patents
3-aminopiroli, postupak za njihovu izradu, kao i izrada farmaceutskih sastava koji ih sadrže 3-aminopirrolesInfo
- Publication number
- YU48469B YU48469B YU217390A YU217390A YU48469B YU 48469 B YU48469 B YU 48469B YU 217390 A YU217390 A YU 217390A YU 217390 A YU217390 A YU 217390A YU 48469 B YU48469 B YU 48469B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- cooch3
- clc6h4
- cooc2h5
- preparation
- brc6h4
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
3-Aminopiroli formule I u kojoj supstituenti R1 do R6 imaju značenja koja odgovaraju sledećim kombinacijama: R1 R2 R3 R4 R5 R6 H COOCH3 CH3 CH3 C6H5 H H COOC2H5 H C6H5 (CH2)4 H COOCH3 (CH2)4 C6H5 H H COOC2H5 (CH2)4 C6H5 H H COOCH3 (CH2)5 4-ClC6H4 H H COOC2H5 (CH2)5 4-CH3C6H5 H H COOH (CH2)2-O-(CH2)2 C6H5 H H COONa (CH2)2-O-(CH2)2 C6H5 H H COOCH3 (CH2)2-O-(CH2)2 3-BrC6H4 H H COOCH3 (CH2)2-O-(CH2)2 4-BrC6H5 H H COOCH3 (CH2)2-O-(CH2)2 4-CH3CH2C6H4 H H COOCH3 (CH2)2-O-(CH2)2 4-FC6H5 H H COOCH3 (CH2)2-O-(CH2)2 3-CH3OC6H4 H H COOCH3 (CH2)2-O-(CH2)2 4-C6H5C6H4 H H COOCH3 (CH2)2-O-(CH2)2 3,4-(CH3O)2C6H3 H H COOCH2C6H5 (CH2)2-O-(CH2)2 C6H5 H H CONHC6H5 (CH2)2-O-(CH2)2 C6H5 H H COCH3 (CH2)2-O-(CH2)2 4-ClC6H4 H CH3 COOCH3 (CH2)2-O-(CH2)2 C6H5 H CH3 COOCH3 (CH2)2-O-(CH2)2 4-CH3C6H4 H CH3 COOCH3 (CH2)2-O-(CH2)2 4-ClC6H4 H CH3 COOC2H5 (CH2)2-O-(CH2)2 4-ClC6H4 H CH3 COOCH3 (CH2)2-O-(CH2)2 4-BrC6H4 H C2H5 COOCH3 (CH2)2-O-(CH2)2 4-BrC6H4 H CH2C6H5 COOCH3 (CH2)2-O-(CH2)2 C6H5 H CH2C6H5 COOCH3 (CH2)2-O-(CH2)2 4-ClC6H4 H CH2COOC2H5 COOCH3 (CH2)2-O-(CH2)2 C6H5 H Prijava sadrži još 2 nezavisna i 3 zavisna zahteva.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI9012173A SI20323B (en) | 1989-11-17 | 1990-11-15 | 3-Aminopyrrole, process for preparation and its use as a pharmaceutical composition or medicine |
HR930229A HRP930229A2 (en) | 1989-11-17 | 1993-02-24 | 3-aminopyrroles, process for their preparation and their use as medicaments |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DD89334670A DD298912A5 (de) | 1989-11-17 | 1989-11-17 | Verfahren zur herstellung von 3-aminopyrrolen |
Publications (2)
Publication Number | Publication Date |
---|---|
YU217390A YU217390A (sh) | 1993-05-28 |
YU48469B true YU48469B (sh) | 1998-08-14 |
Family
ID=5613902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU217390A YU48469B (sh) | 1989-11-17 | 1990-11-15 | 3-aminopiroli, postupak za njihovu izradu, kao i izrada farmaceutskih sastava koji ih sadrže 3-aminopirroles |
Country Status (10)
Country | Link |
---|---|
US (2) | US5502051A (sh) |
EP (1) | EP0431371B1 (sh) |
JP (1) | JPH07113015B2 (sh) |
DD (1) | DD298912A5 (sh) |
DE (1) | DE59010759D1 (sh) |
ES (1) | ES2108005T3 (sh) |
FI (1) | FI102169B (sh) |
HU (1) | HUT56343A (sh) |
RU (2) | RU2060991C1 (sh) |
YU (1) | YU48469B (sh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4227479A1 (de) * | 1992-08-20 | 1994-02-24 | Dresden Arzneimittel | Verfahren zur Herstellung von 1-unsubstituierten 3-Aminopyrrolen |
US5792778A (en) * | 1995-08-10 | 1998-08-11 | Merck & Co., Inc. | 2-substituted aryl pyrroles, compositions containing such compounds and methods of use |
US5837719A (en) * | 1995-08-10 | 1998-11-17 | Merck & Co., Inc. | 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use |
AU7482396A (en) * | 1995-10-31 | 1997-05-22 | Merck & Co., Inc. | Substituted aryl pyrroles, compositions containing such compounds and methods of use |
US5908858A (en) | 1996-04-05 | 1999-06-01 | Sankyo Company, Limited | 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses |
DE19629976A1 (de) * | 1996-07-25 | 1998-01-29 | Dresden Arzneimittel | Verwendung von 4-(p-Halogenphenyl)-3-morpholinopyrrol-2-carbonsäuremethylester zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen |
US5776954A (en) * | 1996-10-30 | 1998-07-07 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
US7122666B2 (en) * | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
CN101801188A (zh) | 2007-07-12 | 2010-08-11 | 特拉加拉医药品公司 | 治疗癌症、肿瘤和肿瘤相关性疾病的方法和组合物 |
US9944597B2 (en) | 2013-09-16 | 2018-04-17 | The Board Of Regents Of The University Of Texas System | Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198502A (en) * | 1973-08-22 | 1980-04-15 | Gruppo Lepetit S.P.A. | Aminopyrrole derivatives |
US4748183A (en) * | 1986-06-13 | 1988-05-31 | Warner-Lambert Company | N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof |
-
1989
- 1989-11-17 DD DD89334670A patent/DD298912A5/de not_active IP Right Cessation
-
1990
- 1990-11-15 YU YU217390A patent/YU48469B/sh unknown
- 1990-11-16 FI FI905689A patent/FI102169B/fi not_active IP Right Cessation
- 1990-11-16 DE DE59010759T patent/DE59010759D1/de not_active Expired - Fee Related
- 1990-11-16 RU SU904831894A patent/RU2060991C1/ru active
- 1990-11-16 JP JP2311258A patent/JPH07113015B2/ja not_active Expired - Lifetime
- 1990-11-16 RU RU94002476A patent/RU2120796C1/ru active
- 1990-11-16 US US07/614,459 patent/US5502051A/en not_active Expired - Fee Related
- 1990-11-16 HU HU907176A patent/HUT56343A/hu unknown
- 1990-11-16 EP EP90121958A patent/EP0431371B1/de not_active Expired - Lifetime
- 1990-11-16 ES ES90121958T patent/ES2108005T3/es not_active Expired - Lifetime
-
1995
- 1995-05-19 US US08/446,000 patent/US5684160A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH03271271A (ja) | 1991-12-03 |
DD298912A5 (de) | 1992-03-19 |
FI905689A0 (fi) | 1990-11-16 |
US5684160A (en) | 1997-11-04 |
EP0431371B1 (de) | 1997-09-10 |
US5502051A (en) | 1996-03-26 |
RU2120796C1 (ru) | 1998-10-27 |
JPH07113015B2 (ja) | 1995-12-06 |
HUT56343A (en) | 1991-08-28 |
ES2108005T3 (es) | 1997-12-16 |
YU217390A (sh) | 1993-05-28 |
FI905689A (fi) | 1991-05-18 |
DE59010759D1 (de) | 1997-10-16 |
FI102169B1 (fi) | 1998-10-30 |
RU2060991C1 (ru) | 1996-05-27 |
FI102169B (fi) | 1998-10-30 |
HU907176D0 (en) | 1991-05-28 |
EP0431371A1 (de) | 1991-06-12 |
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