DD295164A5 - Verfahren zur herstellung von tigogenin-beta-cellobiosid - Google Patents

Verfahren zur herstellung von tigogenin-beta-cellobiosid Download PDF

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Publication number
DD295164A5
DD295164A5 DD90341563A DD34156390A DD295164A5 DD 295164 A5 DD295164 A5 DD 295164A5 DD 90341563 A DD90341563 A DD 90341563A DD 34156390 A DD34156390 A DD 34156390A DD 295164 A5 DD295164 A5 DD 295164A5
Authority
DD
German Democratic Republic
Prior art keywords
tigogenin
cellobioside
formula
synthesis
inert solvent
Prior art date
Application number
DD90341563A
Other languages
German (de)
English (en)
Inventor
Frank J Urban
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD295164A5 publication Critical patent/DD295164A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
DD90341563A 1989-06-13 1990-06-12 Verfahren zur herstellung von tigogenin-beta-cellobiosid DD295164A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/365,588 US5010185A (en) 1989-06-13 1989-06-13 Processes for tigogenin beta-cellobioside

Publications (1)

Publication Number Publication Date
DD295164A5 true DD295164A5 (de) 1991-10-24

Family

ID=23439483

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90341563A DD295164A5 (de) 1989-06-13 1990-06-12 Verfahren zur herstellung von tigogenin-beta-cellobiosid

Country Status (23)

Country Link
US (1) US5010185A (cs)
EP (1) EP0403150B1 (cs)
JP (1) JPH0637514B2 (cs)
KR (1) KR920002146B1 (cs)
AT (1) ATE114155T1 (cs)
AU (1) AU619986B2 (cs)
CA (1) CA2018722A1 (cs)
CZ (1) CZ279909B6 (cs)
DD (1) DD295164A5 (cs)
DE (1) DE69014152T2 (cs)
DK (1) DK0403150T3 (cs)
ES (1) ES2063269T3 (cs)
FI (1) FI902937A7 (cs)
HU (1) HU210689B (cs)
IE (1) IE64057B1 (cs)
IL (1) IL94650A (cs)
NO (1) NO902600L (cs)
NZ (1) NZ234028A (cs)
PL (3) PL163259B1 (cs)
PT (1) PT94337A (cs)
RU (1) RU2042688C1 (cs)
YU (1) YU47515B (cs)
ZA (1) ZA904527B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294703A (en) * 1992-05-01 1994-03-15 Eastman Kodak Company Process for preparing α-D-cellobiose octaacetate
AU4044293A (en) * 1992-06-26 1994-01-24 Pfizer Inc. Process for steroidal peracyl glycosides
AU4226593A (en) * 1992-06-26 1994-01-24 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
FI946081L (fi) * 1992-06-26 1994-12-23 Pfizer Steroidaalinen beta-0-sellobiosidihepta-alkanoaattimenetelmä
US5530107A (en) * 1992-10-15 1996-06-25 Pfizer Inc. Method for making steroidal peracyl glycosides
CZ280195A3 (en) * 1993-04-28 1996-02-14 Pfizer Crystalline spirostanyl glycoside, monohydrate thereof, pharmaceutical composition based thereon and process for preparing crystalline steroidal glycoside
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
ES2074006B1 (es) * 1993-07-05 1996-03-16 Pfizer Glicosidos esteroidales para tratar hipercolesterolemia.
GB9806513D0 (en) * 1998-03-26 1998-05-27 Phytopharm Ltd Membrane-bound receptors
JP4589869B2 (ja) * 2002-07-12 2010-12-01 塩野義製薬株式会社 酸触媒として機能するゼオライト類似体の簡易な製造法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia

Also Published As

Publication number Publication date
KR910000779A (ko) 1991-01-30
NO902600L (no) 1990-12-14
KR920002146B1 (ko) 1992-03-12
HU210689B (en) 1995-06-28
JPH0637514B2 (ja) 1994-05-18
CZ289090A3 (en) 1995-04-12
ZA904527B (en) 1992-01-29
FI902937A0 (fi) 1990-06-12
IL94650A0 (en) 1991-04-15
JPH0331297A (ja) 1991-02-12
IE64057B1 (en) 1995-07-12
DK0403150T3 (da) 1995-01-16
HUT54708A (en) 1991-03-28
PL163258B1 (pl) 1994-02-28
PL289135A1 (en) 1992-02-24
YU47515B (sh) 1995-10-03
FI902937A7 (fi) 1990-12-14
CA2018722A1 (en) 1990-12-13
HU903816D0 (en) 1990-11-28
EP0403150A2 (en) 1990-12-19
ES2063269T3 (es) 1995-01-01
IL94650A (en) 1994-11-11
DE69014152T2 (de) 1995-03-23
CZ279909B6 (cs) 1995-08-16
PL163219B1 (pl) 1994-02-28
IE902101L (en) 1990-12-13
DE69014152D1 (de) 1994-12-22
RU2042688C1 (ru) 1995-08-27
PT94337A (pt) 1991-02-08
NO902600D0 (no) 1990-06-12
AU619986B2 (en) 1992-02-06
ATE114155T1 (de) 1994-12-15
YU114590A (en) 1991-10-31
PL163259B1 (pl) 1994-02-28
PL289136A1 (en) 1992-02-24
NZ234028A (en) 1991-10-25
AU5707990A (en) 1991-08-01
EP0403150B1 (en) 1994-11-17
US5010185A (en) 1991-04-23
EP0403150A3 (en) 1992-06-17
PL285593A1 (en) 1991-07-01
IE902101A1 (en) 1991-01-02

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