IL94650A - Process for sythesis of tigogenin betacellobioside and certain novel cellobioside intermediates therefor - Google Patents
Process for sythesis of tigogenin betacellobioside and certain novel cellobioside intermediates thereforInfo
- Publication number
- IL94650A IL94650A IL9465090A IL9465090A IL94650A IL 94650 A IL94650 A IL 94650A IL 9465090 A IL9465090 A IL 9465090A IL 9465090 A IL9465090 A IL 9465090A IL 94650 A IL94650 A IL 94650A
- Authority
- IL
- Israel
- Prior art keywords
- tigogenin
- cellobioside
- formula
- beta
- inert solvent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compounds Of Unknown Constitution (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/365,588 US5010185A (en) | 1989-06-13 | 1989-06-13 | Processes for tigogenin beta-cellobioside |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL94650A0 IL94650A0 (en) | 1991-04-15 |
| IL94650A true IL94650A (en) | 1994-11-11 |
Family
ID=23439483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9465090A IL94650A (en) | 1989-06-13 | 1990-06-06 | Process for sythesis of tigogenin betacellobioside and certain novel cellobioside intermediates therefor |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5010185A (cs) |
| EP (1) | EP0403150B1 (cs) |
| JP (1) | JPH0637514B2 (cs) |
| KR (1) | KR920002146B1 (cs) |
| AT (1) | ATE114155T1 (cs) |
| AU (1) | AU619986B2 (cs) |
| CA (1) | CA2018722A1 (cs) |
| CZ (1) | CZ279909B6 (cs) |
| DD (1) | DD295164A5 (cs) |
| DE (1) | DE69014152T2 (cs) |
| DK (1) | DK0403150T3 (cs) |
| ES (1) | ES2063269T3 (cs) |
| FI (1) | FI902937A7 (cs) |
| HU (1) | HU210689B (cs) |
| IE (1) | IE64057B1 (cs) |
| IL (1) | IL94650A (cs) |
| NO (1) | NO902600L (cs) |
| NZ (1) | NZ234028A (cs) |
| PL (3) | PL163259B1 (cs) |
| PT (1) | PT94337A (cs) |
| RU (1) | RU2042688C1 (cs) |
| YU (1) | YU47515B (cs) |
| ZA (1) | ZA904527B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5294703A (en) * | 1992-05-01 | 1994-03-15 | Eastman Kodak Company | Process for preparing α-D-cellobiose octaacetate |
| AU4044293A (en) * | 1992-06-26 | 1994-01-24 | Pfizer Inc. | Process for steroidal peracyl glycosides |
| AU4226593A (en) * | 1992-06-26 | 1994-01-24 | Pfizer Inc. | Steroidal glycosides for treating hypercholesterolemia |
| FI946081L (fi) * | 1992-06-26 | 1994-12-23 | Pfizer | Steroidaalinen beta-0-sellobiosidihepta-alkanoaattimenetelmä |
| US5530107A (en) * | 1992-10-15 | 1996-06-25 | Pfizer Inc. | Method for making steroidal peracyl glycosides |
| CZ280195A3 (en) * | 1993-04-28 | 1996-02-14 | Pfizer | Crystalline spirostanyl glycoside, monohydrate thereof, pharmaceutical composition based thereon and process for preparing crystalline steroidal glycoside |
| US5502038A (en) * | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
| ES2074006B1 (es) * | 1993-07-05 | 1996-03-16 | Pfizer | Glicosidos esteroidales para tratar hipercolesterolemia. |
| GB9806513D0 (en) * | 1998-03-26 | 1998-05-27 | Phytopharm Ltd | Membrane-bound receptors |
| JP4589869B2 (ja) * | 2002-07-12 | 2010-12-01 | 塩野義製薬株式会社 | 酸触媒として機能するゼオライト類似体の簡易な製造法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4602005A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis |
| US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
-
1989
- 1989-06-13 US US07/365,588 patent/US5010185A/en not_active Expired - Fee Related
-
1990
- 1990-06-06 DK DK90306143.0T patent/DK0403150T3/da active
- 1990-06-06 IL IL9465090A patent/IL94650A/en not_active IP Right Cessation
- 1990-06-06 EP EP90306143A patent/EP0403150B1/en not_active Expired - Lifetime
- 1990-06-06 AT AT90306143T patent/ATE114155T1/de not_active IP Right Cessation
- 1990-06-06 ES ES90306143T patent/ES2063269T3/es not_active Expired - Lifetime
- 1990-06-06 JP JP2148456A patent/JPH0637514B2/ja not_active Expired - Lifetime
- 1990-06-06 DE DE69014152T patent/DE69014152T2/de not_active Expired - Fee Related
- 1990-06-11 CZ CS902890A patent/CZ279909B6/cs not_active IP Right Cessation
- 1990-06-11 PT PT94337A patent/PT94337A/pt not_active Application Discontinuation
- 1990-06-11 CA CA002018722A patent/CA2018722A1/en not_active Abandoned
- 1990-06-12 HU HU903816A patent/HU210689B/hu not_active IP Right Cessation
- 1990-06-12 AU AU57079/90A patent/AU619986B2/en not_active Ceased
- 1990-06-12 IE IE210190A patent/IE64057B1/en not_active IP Right Cessation
- 1990-06-12 RU SU904830049A patent/RU2042688C1/ru active
- 1990-06-12 NZ NZ234028A patent/NZ234028A/xx unknown
- 1990-06-12 DD DD90341563A patent/DD295164A5/de not_active IP Right Cessation
- 1990-06-12 PL PL90289136A patent/PL163259B1/pl unknown
- 1990-06-12 KR KR1019900008599A patent/KR920002146B1/ko not_active Expired
- 1990-06-12 YU YU114590A patent/YU47515B/sh unknown
- 1990-06-12 ZA ZA904527A patent/ZA904527B/xx unknown
- 1990-06-12 FI FI902937A patent/FI902937A7/fi not_active IP Right Cessation
- 1990-06-12 PL PL90289135A patent/PL163258B1/pl unknown
- 1990-06-12 PL PL90285593A patent/PL163219B1/pl unknown
- 1990-06-12 NO NO90902600A patent/NO902600L/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Jansson et al. | 2-(Trimethylsilyl) ethyl glycosides. Transformation into glycopyranosyl chlorides | |
| US5621087A (en) | Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide | |
| IL94650A (en) | Process for sythesis of tigogenin betacellobioside and certain novel cellobioside intermediates therefor | |
| JP3231765B2 (ja) | デメチルエピポドフィロトキシンの製造方法 | |
| US4758383A (en) | Ergosta-1,5,7,22-tetraen-3β-ol and its use as an intermediate for 1α-hydroxy vitamin D2 | |
| IE53323B1 (en) | Process for the preparation of isosorbide-2-nitrate | |
| US5262531A (en) | Process for preparing 2'-deoxy-β-adenosine | |
| US4923640A (en) | Process for the production of 17α-ethinyl-17β-hydroxy-18-methyl-4,15-estradien-3-one and new intermediate products for this process | |
| EP0829472B1 (en) | Improved process for producing 4-hydroxy-2-pyrrolidone | |
| WO1994000478A1 (en) | Steroidal beta-o-cellobioside heptaalkanoate process | |
| Pozsgay et al. | Synthesis of glycosyl esters and glycosyl hemiacetals from methylthioglycosides | |
| Chida et al. | Facile syntheses of some L-sugar derivatives from L-quebrachitol | |
| US4301276A (en) | Synthesis of daunosamine hydrochloride and intermediates used in its preparation | |
| US5756712A (en) | Peptidodisaccharides as oligosaccharide mimetics | |
| JP2003527397A (ja) | ペルベンジル化１−ｏ−グリコシドの製法 | |
| US4855417A (en) | Anomeric deacetylation | |
| US4880917A (en) | Process for hydrolyzing 2,6-dideoxy-2,6-iminoheptononitrile derivatives using trifluoroacetic acid and dinitrogen tetroxide | |
| US4456766A (en) | Process for the production of N-acetyl-2,3-dehydro-aminocarboxylic acid esters | |
| EP0627396B1 (en) | Cyclohexene diol derivatives | |
| US5606041A (en) | Process for steroidal peracyl glycosides | |
| US4127589A (en) | 4,5-Seco-steroids | |
| Allevi et al. | Synthesis of 7α, 12α-dihydroxy-3α-[2-(β-d-glucopyranosyl) acetyl]-5β-cholan-24-oic acid | |
| HU211082B (hu) | Eljárás tigogenin-ortoészter-származékok előállítására | |
| JPS6039279B2 (ja) | エピデスモステロ−ル誘導体 | |
| EP0582153A1 (en) | Method of preparing 4-deoxy-D-mannose |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |