DD285994A5 - Verfahren zur herstellung eines hbv-impfstoffes - Google Patents
Verfahren zur herstellung eines hbv-impfstoffes Download PDFInfo
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- DD285994A5 DD285994A5 DD88334295A DD33429588A DD285994A5 DD 285994 A5 DD285994 A5 DD 285994A5 DD 88334295 A DD88334295 A DD 88334295A DD 33429588 A DD33429588 A DD 33429588A DD 285994 A5 DD285994 A5 DD 285994A5
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US932587A | 1987-01-30 | 1987-01-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
DD285994A5 true DD285994A5 (de) | 1991-01-10 |
Family
ID=21736956
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD88334296A DD285612A5 (de) | 1987-01-30 | 1988-01-29 | Verfahren zur herstellung eines hiv-impfstoffes |
DD88334295A DD285994A5 (de) | 1987-01-30 | 1988-01-29 | Verfahren zur herstellung eines hbv-impfstoffes |
DD88334294A DD284899A5 (de) | 1987-01-30 | 1988-01-29 | Verfahren zur herstellung eines plasmodium-impfstoffes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD88334296A DD285612A5 (de) | 1987-01-30 | 1988-01-29 | Verfahren zur herstellung eines hiv-impfstoffes |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD88334294A DD284899A5 (de) | 1987-01-30 | 1988-01-29 | Verfahren zur herstellung eines plasmodium-impfstoffes |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0278940A3 (no) |
JP (1) | JPS6463382A (no) |
KR (1) | KR880009130A (no) |
CN (1) | CN1031395A (no) |
AP (1) | AP56A (no) |
AU (1) | AU1093088A (no) |
DD (3) | DD285612A5 (no) |
DK (1) | DK43188A (no) |
FI (1) | FI880428A (no) |
HU (1) | HUT50876A (no) |
IL (1) | IL85216A0 (no) |
MA (1) | MA21169A1 (no) |
NO (1) | NO880395L (no) |
NZ (1) | NZ223297A (no) |
OA (1) | OA08801A (no) |
PT (1) | PT86640B (no) |
SU (1) | SU1746887A3 (no) |
TN (1) | TNSN88004A1 (no) |
YU (1) | YU17488A (no) |
ZA (1) | ZA88488B (no) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE207535T1 (de) * | 1987-06-22 | 2001-11-15 | Medeva Holdings Bv | Hepatitis-b-oberflächenantigen enthaltendes peptid |
IL89991A0 (en) * | 1988-04-25 | 1989-12-15 | Phillips Petroleum Co | Expression of hepatitis b pres2 protein in methylotrophic yeasts |
EP0345792A3 (en) * | 1988-06-10 | 1991-05-02 | F. Hoffmann-La Roche Ag | Htlv-i / hiv-1 fusion proteins |
FR2635532B1 (fr) * | 1988-07-29 | 1992-05-22 | Pasteur Institut | Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant |
US5130247A (en) * | 1989-09-19 | 1992-07-14 | Merck & Co., Inc. | Expression of fusion protein of HIV envelope and HBsAG |
US5130248A (en) * | 1989-09-19 | 1992-07-14 | Merck & Co., Inc. | Expression of fusion protein of HIV envelope and HBsAg |
EP0421626A1 (en) * | 1989-09-19 | 1991-04-10 | Merck & Co. Inc. | Vaccine for aids and hepatitis B |
EP0491077A1 (en) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | A composition used as a therapeutic agent against chronic viral hepatic diseases |
DE69228698T2 (de) * | 1991-11-16 | 1999-09-16 | Smithkline Beecham Biologicals S.A., Rixensart | HYBRIDES PROTEIN ZWISCHEN CS AUS PLASMODIUM UND HBsAG |
WO1993013120A1 (en) * | 1991-12-23 | 1993-07-08 | Chiron Corporation | Hbv amplifier probes for use in solution phase sandwich hybridization assays |
US6297048B1 (en) | 1992-02-04 | 2001-10-02 | Chiron Corporation | Hepatitis therapeutics |
US5928902A (en) * | 1992-02-27 | 1999-07-27 | Smithkline Beecham Biologicals (S.A.) | Hybrid protein between CS from plasmodium and HBsAg |
US6169171B1 (en) | 1992-02-27 | 2001-01-02 | Smithkline Beecham Biologicals (S.A.) | Hybrid protein between CS from plasmodium and HBSAG |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
AU671623B2 (en) * | 1992-03-06 | 1996-09-05 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and biotinylated peptides used therein |
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
EP0565794A1 (en) * | 1992-04-14 | 1993-10-20 | British Biotech Pharmaceuticals Limited | Induction of CTL responses |
PT835663E (pt) | 1992-05-23 | 2010-01-04 | Glaxosmithkline Biolog Sa | Vacinas combinadas compreendendo o antigénio de superfície da hepatite b e outros antigénios |
CN1063343C (zh) * | 1993-04-27 | 2001-03-21 | 中国科学院上海生物化学研究所 | 氨端带前表面抗原决定簇的乙型肝炎表面抗原蛋白 |
US6235888B1 (en) | 1994-10-05 | 2001-05-22 | The General Hospital Corporation | Hepatitis C virus vaccine |
RU2189254C2 (ru) * | 1995-06-06 | 2002-09-20 | Америкэн Хоум Продактс Корпорэйшн | Вакцины против вирусов гепатита |
JP4383530B2 (ja) | 1996-04-05 | 2009-12-16 | ノバルティス バクシンズ アンド ダイアグノスティックス, インコーポレーテッド | 細胞巨大分子合成の阻害が減少したアルファウイルスベクター |
CA2266656A1 (en) | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
GB9623233D0 (en) | 1996-11-07 | 1997-01-08 | Smithkline Beecham Biolog | Vaccine composition |
CA2773698C (en) | 1998-10-16 | 2015-05-19 | Glaxosmithkline Biologicals S.A. | Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof |
UA79735C2 (uk) * | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
CN100381171C (zh) * | 2004-12-30 | 2008-04-16 | 成都生物制品研究所 | 含前s1、前s2和s抗原决定簇的乙肝表面抗原复合颗粒 |
CN102675430B (zh) * | 2005-08-12 | 2014-08-27 | 上海贺普药业股份有限公司 | 乙型肝炎病毒表面l蛋白相关肽 |
BRPI0708912B8 (pt) | 2006-03-14 | 2021-07-27 | Univ Oregon Health & Science | métodos in vitro para detecção de mycobacterium tuberculosis e de células t expressando cd8 que especificamente reconhecem seq id no: 11 em um indivíduo |
MX2009002560A (es) | 2006-09-07 | 2009-03-20 | Glaxosmithkline Biolog Sa | Vacuna. |
KR100836745B1 (ko) * | 2007-01-31 | 2008-06-10 | (주)두비엘 | Hbv 백신 및 그의 제조 방법 |
EP2444410A3 (en) | 2007-02-28 | 2012-08-08 | The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
EA201490303A1 (ru) | 2007-05-02 | 2014-05-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина |
EP2293813A4 (en) | 2008-05-23 | 2012-07-11 | Univ Michigan | NANOEMULSION VACCINES |
WO2010099472A2 (en) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Spanx-b polypeptides and their use |
GB201105981D0 (en) | 2011-04-08 | 2011-05-18 | Glaxosmithkline Biolog Sa | Novel process |
WO2014043518A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use |
EP3331554B1 (en) | 2015-08-03 | 2022-05-11 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2145092B (en) * | 1983-01-28 | 1988-04-07 | Univ New York | Protective peptide antigen |
AU584580B2 (en) * | 1982-09-08 | 1989-06-01 | Smith Kline - Rit | Hepatitis B virus vaccine |
DE3585578D1 (de) * | 1984-06-18 | 1992-04-16 | Chiron Corp | Hepatitisoberflaechenantigenpartikelvakzin. |
EP0401941A3 (en) * | 1984-07-11 | 1991-04-17 | Takeda Chemical Industries, Ltd. | Hepatitis b virus surface antigen and production thereof |
GB8421282D0 (en) * | 1984-08-22 | 1984-09-26 | Connaught Lab | Multispecific antigenic proteins |
EP0175261B1 (en) * | 1984-09-12 | 1991-12-11 | Chiron Corporation | Hybrid particle immunogens |
EP0180012A1 (de) * | 1984-10-27 | 1986-05-07 | Wolfram H. Prof. Dr. Gerlich | Immunogene Polypeptidsequenz des Hepatitis B-Virus |
CN86100979A (zh) * | 1985-02-07 | 1986-12-17 | 史密丝克莱恩贝克曼公司 | 疟疾疫苗的制备方法 |
US4774175A (en) * | 1985-03-01 | 1988-09-27 | Centocor, Inc. | Immunochemical methods for the detection of antibody against HTLV-III |
US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
WO1986006077A1 (en) * | 1985-04-08 | 1986-10-23 | Amgen | A method and a hybrid promoter for controlling exogenous gene transcription |
FR2581394B1 (fr) * | 1985-05-02 | 1988-08-05 | Grp Genie Genetique | Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes |
US4816564A (en) * | 1986-01-31 | 1989-03-28 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
CA1310602C (en) * | 1986-06-03 | 1992-11-24 | Hajime Horii | Yeast promoter and process for preparing heterologous protein |
-
1988
- 1988-01-25 ZA ZA88488A patent/ZA88488B/xx unknown
- 1988-01-25 AP APAP/P/1988/000078A patent/AP56A/en active
- 1988-01-25 EP EP88870008A patent/EP0278940A3/en not_active Withdrawn
- 1988-01-26 NZ NZ223297A patent/NZ223297A/en unknown
- 1988-01-26 SU SU884355055A patent/SU1746887A3/ru active
- 1988-01-26 IL IL85216A patent/IL85216A0/xx unknown
- 1988-01-27 OA OA59269A patent/OA08801A/xx unknown
- 1988-01-27 PT PT86640A patent/PT86640B/pt not_active IP Right Cessation
- 1988-01-28 AU AU10930/88A patent/AU1093088A/en not_active Abandoned
- 1988-01-28 DK DK043188A patent/DK43188A/da not_active Application Discontinuation
- 1988-01-29 DD DD88334296A patent/DD285612A5/de unknown
- 1988-01-29 FI FI880428A patent/FI880428A/fi not_active IP Right Cessation
- 1988-01-29 HU HU88409A patent/HUT50876A/hu unknown
- 1988-01-29 YU YU00174/88A patent/YU17488A/xx unknown
- 1988-01-29 DD DD88334295A patent/DD285994A5/de not_active IP Right Cessation
- 1988-01-29 JP JP63021137A patent/JPS6463382A/ja active Pending
- 1988-01-29 MA MA21406A patent/MA21169A1/fr unknown
- 1988-01-29 DD DD88334294A patent/DD284899A5/de not_active IP Right Cessation
- 1988-01-29 NO NO880395A patent/NO880395L/no unknown
- 1988-01-30 KR KR1019880000825A patent/KR880009130A/ko not_active Application Discontinuation
- 1988-01-30 CN CN88100483A patent/CN1031395A/zh active Pending
- 1988-02-03 TN TNTNSN88004A patent/TNSN88004A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
YU17488A (en) | 1991-02-28 |
AU1093088A (en) | 1988-08-04 |
TNSN88004A1 (fr) | 1990-07-10 |
FI880428A (fi) | 1988-09-13 |
EP0278940A2 (en) | 1988-08-17 |
SU1746887A3 (ru) | 1992-07-07 |
DK43188D0 (da) | 1988-01-28 |
IL85216A0 (en) | 1988-07-31 |
OA08801A (fr) | 1989-03-31 |
FI880428A0 (fi) | 1988-01-29 |
PT86640A (pt) | 1988-02-01 |
EP0278940A3 (en) | 1988-12-07 |
PT86640B (pt) | 1992-01-31 |
NO880395L (no) | 1988-08-01 |
MA21169A1 (fr) | 1988-10-01 |
NZ223297A (en) | 1991-06-25 |
HUT50876A (en) | 1990-03-28 |
ZA88488B (en) | 1988-10-26 |
AP56A (en) | 1989-09-26 |
DD284899A5 (de) | 1990-11-28 |
DK43188A (da) | 1988-07-31 |
NO880395D0 (no) | 1988-01-29 |
JPS6463382A (en) | 1989-03-09 |
KR880009130A (ko) | 1988-09-14 |
AP8800078A0 (en) | 1987-11-01 |
CN1031395A (zh) | 1989-03-01 |
DD285612A5 (de) | 1990-12-19 |
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