DD245874A5 - Verfahren zur herstellung fluorierter benzyltriazolverbindungen - Google Patents

Verfahren zur herstellung fluorierter benzyltriazolverbindungen Download PDF

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Publication number
DD245874A5
DD245874A5 DD86289243A DD28924386A DD245874A5 DD 245874 A5 DD245874 A5 DD 245874A5 DD 86289243 A DD86289243 A DD 86289243A DD 28924386 A DD28924386 A DD 28924386A DD 245874 A5 DD245874 A5 DD 245874A5
Authority
DD
German Democratic Republic
Prior art keywords
triazole
item
carbamyl
formula
produces
Prior art date
Application number
DD86289243A
Other languages
German (de)
English (en)
Inventor
Rene Meier
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD245874A5 publication Critical patent/DD245874A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD86289243A 1985-04-18 1986-04-16 Verfahren zur herstellung fluorierter benzyltriazolverbindungen DD245874A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (1)

Publication Number Publication Date
DD245874A5 true DD245874A5 (de) 1987-05-20

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86289243A DD245874A5 (de) 1985-04-18 1986-04-16 Verfahren zur herstellung fluorierter benzyltriazolverbindungen

Country Status (22)

Country Link
EP (1) EP0199262B1 (xx)
JP (1) JPS61243068A (xx)
KR (1) KR900008810B1 (xx)
AU (1) AU599024B2 (xx)
CA (1) CA1272201A (xx)
CY (1) CY1751A (xx)
DD (1) DD245874A5 (xx)
DE (1) DE3677626D1 (xx)
DK (1) DK169720B1 (xx)
ES (2) ES8800176A1 (xx)
FI (1) FI93544C (xx)
GR (1) GR861004B (xx)
HK (1) HK1494A (xx)
HU (1) HU203327B (xx)
IE (1) IE58472B1 (xx)
IL (1) IL78510A (xx)
MX (1) MX9203628A (xx)
NO (1) NO164295C (xx)
NZ (1) NZ215871A (xx)
PH (1) PH22568A (xx)
PT (1) PT82400B (xx)
ZA (1) ZA862873B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
WO1997040025A1 (en) * 1996-04-19 1997-10-30 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
JP3537147B2 (ja) 1996-07-11 2004-06-14 ノバルティス アクチエンゲゼルシャフト １―置換４―シアノ―１，２，３―トリアゾールの製造法
TW403740B (en) * 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
JP2013525413A (ja) * 2010-04-30 2013-06-20 ラボラトリオス レスヴィ，エス．エル． ルフィナマイド中間体の改良された製造方法
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014120994A1 (en) * 2013-01-31 2014-08-07 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
WO2017097311A1 (en) 2015-12-11 2017-06-15 Aarhus Universitet Rufinamide for use in the treatment of myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
GR861004B (en) 1986-08-12
DK175686A (da) 1986-10-19
DE3677626D1 (de) 1991-04-04
NO164295B (no) 1990-06-11
AU5631986A (en) 1986-10-23
IL78510A0 (en) 1986-08-31
ES557641A0 (es) 1988-07-01
DK175686D0 (da) 1986-04-17
NZ215871A (en) 1989-01-27
NO164295C (no) 1990-09-19
HK1494A (en) 1994-01-14
IL78510A (en) 1992-05-25
HU203327B (en) 1991-07-29
KR900008810B1 (ko) 1990-11-30
FI93544C (fi) 1995-04-25
EP0199262B1 (de) 1991-02-27
KR860008152A (ko) 1986-11-12
HUT40792A (en) 1987-02-27
JPS61243068A (ja) 1986-10-29
ZA862873B (en) 1986-12-30
JPH0564949B2 (xx) 1993-09-16
CA1272201A (en) 1990-07-31
FI93544B (fi) 1995-01-13
ES554024A0 (es) 1987-10-16
PT82400B (pt) 1988-08-17
PT82400A (en) 1986-05-01
ES8800176A1 (es) 1987-10-16
MX9203628A (es) 1992-09-01
CY1751A (en) 1994-06-03
DK169720B1 (da) 1995-01-23
EP0199262A3 (en) 1987-08-26
IE58472B1 (en) 1993-09-22
FI861573A (fi) 1986-10-19
FI861573A0 (fi) 1986-04-14
PH22568A (en) 1988-10-17
AU599024B2 (en) 1990-07-12
ES8802501A1 (es) 1988-07-01
NO861486L (no) 1986-10-20
IE861015L (en) 1986-10-18
EP0199262A2 (de) 1986-10-29

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