DD209828A5 - Verfahren zur herstellung von 2-guanidino-4-(2-subst.-amino-4-imidazolyl)thiazolen - Google Patents
Verfahren zur herstellung von 2-guanidino-4-(2-subst.-amino-4-imidazolyl)thiazolen Download PDFInfo
- Publication number
- DD209828A5 DD209828A5 DD83250744A DD25074483A DD209828A5 DD 209828 A5 DD209828 A5 DD 209828A5 DD 83250744 A DD83250744 A DD 83250744A DD 25074483 A DD25074483 A DD 25074483A DD 209828 A5 DD209828 A5 DD 209828A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- formula
- alkyl
- meaning
- item
- nhr
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Lubricants (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/376,486 US4435396A (en) | 1982-05-10 | 1982-05-10 | Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD209828A5 true DD209828A5 (de) | 1984-05-23 |
Family
ID=23485203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD83250744A DD209828A5 (de) | 1982-05-10 | 1983-05-09 | Verfahren zur herstellung von 2-guanidino-4-(2-subst.-amino-4-imidazolyl)thiazolen |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4435396A (es) |
| EP (1) | EP0094191B1 (es) |
| JP (1) | JPS58206588A (es) |
| KR (1) | KR860000931B1 (es) |
| AT (1) | ATE33649T1 (es) |
| AU (2) | AU539244B2 (es) |
| CA (1) | CA1201120A (es) |
| CS (1) | CS252461B2 (es) |
| DD (1) | DD209828A5 (es) |
| DE (1) | DE3376322D1 (es) |
| DK (1) | DK163829B (es) |
| EG (1) | EG17029A (es) |
| ES (1) | ES522223A0 (es) |
| FI (1) | FI78481C (es) |
| GR (1) | GR79279B (es) |
| GT (1) | GT198302123A (es) |
| HU (2) | HU190899B (es) |
| IE (1) | IE55229B1 (es) |
| IL (1) | IL68630A (es) |
| NO (1) | NO159932C (es) |
| NZ (1) | NZ204158A (es) |
| PL (1) | PL141199B1 (es) |
| PT (1) | PT76662B (es) |
| SU (1) | SU1195907A3 (es) |
| YU (1) | YU42857B (es) |
| ZA (1) | ZA833286B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554276A (en) * | 1983-10-03 | 1985-11-19 | Pfizer Inc. | 2-Amino-5-hydroxy-4-methylpyrimidine derivatives |
| US4673677A (en) * | 1983-10-03 | 1987-06-16 | Pfizer Inc. | Method for treatment of gastrointestinal disorders |
| US4560690A (en) * | 1984-04-30 | 1985-12-24 | Pfizer Inc. | 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents |
| US4636498A (en) * | 1984-10-11 | 1987-01-13 | Pfizer Inc. | Formulation of antiinflammatory drugs |
| US4632993A (en) * | 1984-10-11 | 1986-12-30 | Pfizer Inc. | Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide |
| WO1986003203A1 (en) * | 1984-11-22 | 1986-06-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienylthiazole derivatives |
| US4814341A (en) * | 1986-08-26 | 1989-03-21 | Reiter Lawrence A | 2-guanidino-4-(2-furyl) thiazoles as antiulcer agents |
| ES2031514T3 (es) * | 1986-08-29 | 1992-12-16 | Pfizer Inc. | 2-guanidino-4-ariltiazoles para el tratamiento de ulceras pepticas. |
| DE3750023T2 (de) * | 1986-10-29 | 1994-09-29 | Pfizer | Verfahren zur Herstellung von 2-(1-Pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)Thiazol und dessen kristallinisches Dihydrochlorid-Trihydrat. |
| CA2165344A1 (en) * | 1993-06-15 | 1994-12-22 | Peter C. Canning | Immune stimulants in bacterial infections |
| KR101406433B1 (ko) | 2008-09-22 | 2014-06-13 | 카이맨 케미칼 컴파니 인코포레이티드 | Ｈ-ｐｇｄｓ 억제제로서 다중헤테로아릴 화합물 및 프로스타글란딘 ｄ2 매개된 질병의 치료를 위한 그의 용도 |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3519637A (en) | 1966-12-06 | 1970-07-07 | Hoffmann La Roche | 1-(4-thiazolylmethyl)nitroimidazole derivatives |
| DE2142585A1 (de) * | 1971-08-20 | 1973-02-22 | Schering Ag | 2-(5-nitro-2-thiazolyl)-benzimidazole |
| FR2284601A1 (fr) * | 1974-09-10 | 1976-04-09 | Inst Francais Du Petrole | Composes guanidino-heterocycliques alkyles, leur preparation et leur utilisation comme additifs pour carburants et lubrifiants |
| US4220654A (en) | 1979-06-04 | 1980-09-02 | Merck & Co., Inc. | Cyclic imidazole cyanoguanidines |
| US4374843A (en) | 1980-10-14 | 1983-02-22 | Pfizer Inc. | 2-Guanidino-4-heteroarylthiazoles |
-
1982
- 1982-05-10 US US06/376,486 patent/US4435396A/en not_active Expired - Fee Related
-
1983
- 1983-05-03 SU SU833585699A patent/SU1195907A3/ru active
- 1983-05-04 GR GR71297A patent/GR79279B/el unknown
- 1983-05-04 AT AT83302495T patent/ATE33649T1/de not_active IP Right Cessation
- 1983-05-04 EP EP83302495A patent/EP0094191B1/en not_active Expired
- 1983-05-04 DE DE8383302495T patent/DE3376322D1/de not_active Expired
- 1983-05-05 CS CS833184A patent/CS252461B2/cs unknown
- 1983-05-05 YU YU996/83A patent/YU42857B/xx unknown
- 1983-05-06 HU HU831581A patent/HU190899B/hu not_active IP Right Cessation
- 1983-05-06 CA CA000427596A patent/CA1201120A/en not_active Expired
- 1983-05-06 HU HU862387A patent/HU196377B/hu not_active IP Right Cessation
- 1983-05-06 GT GT198302123A patent/GT198302123A/es unknown
- 1983-05-06 PL PL1983241840A patent/PL141199B1/pl unknown
- 1983-05-06 NZ NZ204158A patent/NZ204158A/en unknown
- 1983-05-07 EG EG275/83A patent/EG17029A/xx active
- 1983-05-09 DK DK205883A patent/DK163829B/da not_active Application Discontinuation
- 1983-05-09 ES ES522223A patent/ES522223A0/es active Granted
- 1983-05-09 NO NO831632A patent/NO159932C/no unknown
- 1983-05-09 DD DD83250744A patent/DD209828A5/de not_active IP Right Cessation
- 1983-05-09 IL IL68630A patent/IL68630A/xx unknown
- 1983-05-09 IE IE1061/83A patent/IE55229B1/en unknown
- 1983-05-09 FI FI831595A patent/FI78481C/fi not_active IP Right Cessation
- 1983-05-09 AU AU14363/83A patent/AU539244B2/en not_active Ceased
- 1983-05-09 KR KR1019830001962A patent/KR860000931B1/ko not_active IP Right Cessation
- 1983-05-09 ZA ZA833286A patent/ZA833286B/xx unknown
- 1983-05-09 PT PT76662A patent/PT76662B/pt unknown
- 1983-05-10 JP JP58081601A patent/JPS58206588A/ja active Pending
-
1984
- 1984-07-18 AU AU30815/84A patent/AU566755B2/en not_active Ceased
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NPV | Change in the person, the name or the address of the representative (addendum to changes before extension act) | ||
| ENJ | Ceased due to non-payment of renewal fee |