DD151750A5 - Verfahren zur herstellung von thiadiazolo-und oxadiazolotetrahydroisochinolinen - Google Patents

Verfahren zur herstellung von thiadiazolo-und oxadiazolotetrahydroisochinolinen Download PDF

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Publication number
DD151750A5
DD151750A5 DD80222268A DD22226880A DD151750A5 DD 151750 A5 DD151750 A5 DD 151750A5 DD 80222268 A DD80222268 A DD 80222268A DD 22226880 A DD22226880 A DD 22226880A DD 151750 A5 DD151750 A5 DD 151750A5
Authority
DD
German Democratic Republic
Prior art keywords
tetrahydroisoquinoline
acetyl
preparation
amino
thiadiazolo
Prior art date
Application number
DD80222268A
Other languages
German (de)
English (en)
Inventor
William E Bondinell
Gerald R Girard
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of DD151750A5 publication Critical patent/DD151750A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD80222268A 1979-07-02 1980-06-30 Verfahren zur herstellung von thiadiazolo-und oxadiazolotetrahydroisochinolinen DD151750A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5434379A 1979-07-02 1979-07-02

Publications (1)

Publication Number Publication Date
DD151750A5 true DD151750A5 (de) 1981-11-04

Family

ID=21990408

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80222268A DD151750A5 (de) 1979-07-02 1980-06-30 Verfahren zur herstellung von thiadiazolo-und oxadiazolotetrahydroisochinolinen

Country Status (30)

Country Link
EP (1) EP0023761B1 (ro)
JP (1) JPS5610192A (ro)
KR (1) KR840000396B1 (ro)
AR (1) AR225925A1 (ro)
AT (1) ATE6515T1 (ro)
AU (1) AU531641B2 (ro)
BG (1) BG51250A3 (ro)
CA (1) CA1129415A (ro)
CS (1) CS215064B2 (ro)
DD (1) DD151750A5 (ro)
DE (1) DE3066826D1 (ro)
DK (1) DK151029C (ro)
ES (1) ES492971A0 (ro)
FI (1) FI67221C (ro)
GR (1) GR69206B (ro)
HU (1) HU179382B (ro)
IE (1) IE50290B1 (ro)
IL (1) IL60426A (ro)
IN (1) IN160542B (ro)
MX (1) MX6317E (ro)
NO (1) NO801951L (ro)
NZ (1) NZ194156A (ro)
PH (1) PH17042A (ro)
PL (2) PL230619A1 (ro)
PT (1) PT71458A (ro)
RO (1) RO79707A (ro)
SU (1) SU1072809A3 (ro)
YU (1) YU171180A (ro)
ZA (1) ZA802987B (ro)
ZW (1) ZW14680A1 (ro)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352809A (en) * 1981-09-04 1982-10-05 Smithkline Corporation Method of producing alpha2 antagonism

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988339A (en) * 1974-02-08 1976-10-26 Smithkline Corporation Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase
US3939164A (en) * 1974-02-08 1976-02-17 Smithkline Corporation 7 AND 8-Halo substituted 1,2,3,4-tetrahydroisoquinoline compounds

Also Published As

Publication number Publication date
FI67221B (fi) 1984-10-31
EP0023761B1 (en) 1984-03-07
JPS5610192A (en) 1981-02-02
NO801951L (no) 1981-01-05
HU179382B (en) 1982-10-28
ES8105736A1 (es) 1981-06-01
IL60426A (en) 1984-03-30
DK151029B (da) 1987-10-12
DK274280A (da) 1981-01-03
AU5967780A (en) 1981-01-15
KR830002791A (ko) 1983-05-30
YU171180A (en) 1983-09-30
NZ194156A (en) 1983-03-15
RO79707A (ro) 1982-08-17
IE801352L (en) 1981-01-02
ES492971A0 (es) 1981-06-01
PH17042A (en) 1984-05-17
EP0023761A1 (en) 1981-02-11
CA1129415A (en) 1982-08-10
DK151029C (da) 1988-03-07
DE3066826D1 (en) 1984-04-12
BG51250A3 (en) 1993-03-15
ATE6515T1 (de) 1984-03-15
ZW14680A1 (en) 1980-09-24
CS215064B2 (en) 1982-07-30
PL225377A1 (ro) 1981-08-21
PL127098B1 (en) 1983-09-30
KR840000396B1 (ko) 1984-03-30
IE50290B1 (en) 1986-03-19
PT71458A (en) 1980-07-01
GR69206B (ro) 1982-05-07
FI802112A (fi) 1981-01-03
FI67221C (fi) 1985-02-11
IN160542B (ro) 1987-07-18
IL60426A0 (en) 1980-09-16
ZA802987B (en) 1981-05-27
AU531641B2 (en) 1983-09-01
SU1072809A3 (ru) 1984-02-07
MX6317E (es) 1985-04-01
PL230619A1 (ro) 1981-12-11
AR225925A1 (es) 1982-05-14

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