DD140746A5 - Verfahren zur herstellung von prostaglandinantagonisten - Google Patents
Verfahren zur herstellung von prostaglandinantagonisten Download PDFInfo
- Publication number
- DD140746A5 DD140746A5 DD78206923A DD20692378A DD140746A5 DD 140746 A5 DD140746 A5 DD 140746A5 DD 78206923 A DD78206923 A DD 78206923A DD 20692378 A DD20692378 A DD 20692378A DD 140746 A5 DD140746 A5 DD 140746A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- acid
- thiepin
- mixture
- dihydro
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81919977A | 1977-07-26 | 1977-07-26 | |
| US91721278A | 1978-06-23 | 1978-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD140746A5 true DD140746A5 (de) | 1980-03-26 |
Family
ID=27124337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD78206923A DD140746A5 (de) | 1977-07-26 | 1978-07-25 | Verfahren zur herstellung von prostaglandinantagonisten |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0011067B1 (es) |
| JP (1) | JPS5444691A (es) |
| AR (2) | AR226527A1 (es) |
| AU (1) | AU517813B2 (es) |
| CA (1) | CA1128048A (es) |
| DD (1) | DD140746A5 (es) |
| DE (1) | DE2861754D1 (es) |
| DK (1) | DK330578A (es) |
| ES (5) | ES471871A1 (es) |
| FI (1) | FI782323A (es) |
| GR (1) | GR67276B (es) |
| IE (1) | IE47553B1 (es) |
| IT (1) | IT1107485B (es) |
| NO (1) | NO782539L (es) |
| PL (3) | PL116355B1 (es) |
| PT (1) | PT68303A (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536507A (en) * | 1977-07-26 | 1985-08-20 | Merck & Co., Inc. | Prostaglandin antagonists |
| PT71280B (en) * | 1979-06-01 | 1981-09-17 | Merck & Co Inc | Process for preparing prostaglandin antagonists |
| US4237160A (en) * | 1979-11-27 | 1980-12-02 | Merck Sharp & Dohme (I.A.) Corp. | 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists |
| EP0029587B1 (en) * | 1979-11-27 | 1984-06-13 | Merck Sharp & Dohme (I.A.) Corp. | 3-hydroxymethyldibenzo(b,f)thiepins and dibenzo(b,f)thiepin-3-carboxaldehydes as prostaglandin antagonists, process for their preparation and pharmaceutical compositions |
| NO811187L (no) * | 1980-11-24 | 1982-05-25 | Merck & Co Inc | Fremgangsmaate ved fremstilling av 7-fluor-dibenzo-(b,f)-thiepinderivater |
| US4535171A (en) * | 1982-11-18 | 1985-08-13 | Merck Frosst Canada, Inc. | Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists |
| US4622403A (en) * | 1983-10-11 | 1986-11-11 | Merck Frosst Canada, Inc. | 6-H dibenz[b,f]thiepin compounds |
| US4663347A (en) | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
| CA1309557C (en) | 1985-06-18 | 1992-10-27 | Robert N. Young | Leukotriene antagonists |
| EP0239306B1 (en) | 1986-03-27 | 1993-06-02 | Merck Frosst Canada Inc. | Tetrahydrocarbazole esters |
| HUT61980A (en) | 1990-10-12 | 1993-03-29 | Merck Frosst Canada Inc | Process for producing saturated hydroxyalkylquinoline acids and pharmaceutical compositions comprising such compounds as active ingredient |
| US5410054A (en) * | 1993-07-20 | 1995-04-25 | Merck Frosst Canada, Inc. | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis |
| EP0885610A4 (en) * | 1996-01-19 | 1999-04-21 | Nippon Suisan Kaisha Ltd | RELAXING SMOOTH MUSCLES OF THE TRACHEA |
| DK1182200T3 (da) | 1999-06-03 | 2005-12-27 | Nippon Suisan Kaisha Ltd | Tricykliske kondenserede heterocykliske forbindelser, fremgangsmåde til fremstilling deraf og anvendelse deraf |
| TWI275495B (en) * | 2004-09-21 | 2007-03-11 | Sony Corp | Printer and printing method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4101667A (en) * | 1975-05-30 | 1978-07-18 | Nippon Chemiphar Co., Ltd. | Benzo[b,f]thiepin derivatives |
| JPS5346989A (en) * | 1976-10-06 | 1978-04-27 | Nippon Chemiphar Co Ltd | Novel dibenzo(b,f)thiepin derivatives and their preparation |
| JPS6021156B2 (ja) * | 1976-12-03 | 1985-05-25 | 日本ケミフア株式会社 | ベンゾチエピン誘導体およびその製法 |
-
1978
- 1978-07-17 PT PT68303A patent/PT68303A/pt unknown
- 1978-07-19 IT IT50375/78A patent/IT1107485B/it active
- 1978-07-19 AU AU38177/78A patent/AU517813B2/en not_active Expired
- 1978-07-19 GR GR56820A patent/GR67276B/el unknown
- 1978-07-19 ES ES471871A patent/ES471871A1/es not_active Expired
- 1978-07-21 AR AR273031A patent/AR226527A1/es active
- 1978-07-21 EP EP78300183A patent/EP0011067B1/en not_active Expired
- 1978-07-21 DE DE7878300183T patent/DE2861754D1/de not_active Expired
- 1978-07-24 NO NO782539A patent/NO782539L/no unknown
- 1978-07-25 IE IE1488/78A patent/IE47553B1/en unknown
- 1978-07-25 FI FI782323A patent/FI782323A/fi not_active Application Discontinuation
- 1978-07-25 DD DD78206923A patent/DD140746A5/de unknown
- 1978-07-25 CA CA308,068A patent/CA1128048A/en not_active Expired
- 1978-07-25 DK DK330578A patent/DK330578A/da not_active Application Discontinuation
- 1978-07-26 PL PL1978208653A patent/PL116355B1/pl unknown
- 1978-07-26 PL PL1978219619A patent/PL117756B1/pl unknown
- 1978-07-26 JP JP9054978A patent/JPS5444691A/ja active Granted
- 1978-07-26 PL PL1978225727A patent/PL120813B1/pl unknown
-
1979
- 1979-04-02 ES ES479216A patent/ES479216A1/es not_active Expired
- 1979-04-02 ES ES479217A patent/ES479217A1/es not_active Expired
- 1979-04-02 ES ES479215A patent/ES479215A1/es not_active Expired
- 1979-04-02 ES ES479218A patent/ES479218A1/es not_active Expired
- 1979-09-20 AR AR278140A patent/AR222666A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IT7850375A0 (it) | 1978-07-19 |
| AR222666A1 (es) | 1981-06-15 |
| ES479216A1 (es) | 1979-07-01 |
| CA1128048A (en) | 1982-07-20 |
| ES471871A1 (es) | 1979-10-01 |
| IE781488L (en) | 1979-01-26 |
| AU3817778A (en) | 1980-01-24 |
| PL117756B1 (en) | 1981-08-31 |
| NO782539L (no) | 1979-01-29 |
| EP0011067A1 (en) | 1980-05-28 |
| JPS6250470B2 (es) | 1987-10-24 |
| IE47553B1 (en) | 1984-04-18 |
| ES479217A1 (es) | 1979-07-01 |
| AU517813B2 (en) | 1981-08-27 |
| AR226527A1 (es) | 1982-07-30 |
| PL208653A1 (pl) | 1979-06-04 |
| GR67276B (es) | 1981-06-26 |
| JPS5444691A (en) | 1979-04-09 |
| DK330578A (da) | 1979-01-27 |
| ES479218A1 (es) | 1979-11-01 |
| ES479215A1 (es) | 1979-07-01 |
| DE2861754D1 (en) | 1982-06-03 |
| EP0011067B1 (en) | 1982-04-21 |
| PL120813B1 (en) | 1982-03-31 |
| FI782323A (fi) | 1979-01-27 |
| IT1107485B (it) | 1985-11-25 |
| PL116355B1 (en) | 1981-06-30 |
| PT68303A (en) | 1978-08-01 |
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