CZ45897A3 - Novel n-substituted naphthocondensated lactams - Google Patents
Novel n-substituted naphthocondensated lactams Download PDFInfo
- Publication number
- CZ45897A3 CZ45897A3 CZ97458A CZ45897A CZ45897A3 CZ 45897 A3 CZ45897 A3 CZ 45897A3 CZ 97458 A CZ97458 A CZ 97458A CZ 45897 A CZ45897 A CZ 45897A CZ 45897 A3 CZ45897 A3 CZ 45897A3
- Authority
- CZ
- Czechia
- Prior art keywords
- alkyl
- oxo
- naphtho
- tetrahydro
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK95294 | 1994-08-17 | ||
| PCT/DK1995/000332 WO1996005195A1 (en) | 1994-08-17 | 1995-08-17 | Novel n-substituted naphthofused lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ45897A3 true CZ45897A3 (en) | 1997-10-15 |
Family
ID=8099355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ97458A CZ45897A3 (en) | 1994-08-17 | 1995-08-17 | Novel n-substituted naphthocondensated lactams |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5817654A (no) |
| EP (1) | EP0777668A1 (no) |
| JP (1) | JPH10504293A (no) |
| CN (1) | CN1158127A (no) |
| AU (1) | AU697003B2 (no) |
| BR (1) | BR9508805A (no) |
| CA (1) | CA2196877A1 (no) |
| CZ (1) | CZ45897A3 (no) |
| HU (1) | HUT76645A (no) |
| IL (1) | IL114955A (no) |
| MX (1) | MX9701187A (no) |
| NO (1) | NO970684L (no) |
| PL (1) | PL318633A1 (no) |
| TW (1) | TW321640B (no) |
| WO (1) | WO1996005195A1 (no) |
| ZA (1) | ZA956869B (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6211174B1 (en) | 1997-10-31 | 2001-04-03 | Merck & Co., Inc. | Naphtho-fused lactams promote release of growth hormone |
| US6380184B1 (en) | 1998-10-28 | 2002-04-30 | Bristol-Myers Squibb Co. | Benzoazepines and analogs thereof useful as growth hormone secretagogues |
| AU759022B2 (en) | 1999-02-18 | 2003-04-03 | Kaken Pharmaceutical Co., Ltd. | Novel amide derivatives as growth hormone secretagogues |
| US6518292B1 (en) | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
| US6525203B1 (en) | 1999-03-12 | 2003-02-25 | Bristol-Myers Squibb Company | Heterocyclic aromatic compounds useful as growth hormone secretagogues |
| MXPA02000142A (es) * | 1999-06-30 | 2003-07-21 | Hamilton Civic Hospitals Res | Composiciones de heparina que inhiben los factores de coagulacion asociados con el coagulo. |
| ATE310728T1 (de) | 2000-05-11 | 2005-12-15 | Bristol Myers Squibb Co | Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga |
| JP2004507562A (ja) * | 2000-09-08 | 2004-03-11 | ハミルトン シビック ホスピタルズ リサーチ ディベロップメント インコーポレイテッド | 抗血栓性組成物 |
| AU2002357692A1 (en) | 2001-11-09 | 2003-05-26 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
| WO2013190520A2 (en) | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | Gh-releasing agents in the treatment of vascular stenosis and associated conditions |
| US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
| US20170121385A1 (en) | 2015-10-28 | 2017-05-04 | Oxeia Biopharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
| CN109071504B (zh) | 2016-02-05 | 2022-03-08 | 戴纳立制药公司 | 受体相互作用蛋白激酶1的抑制剂 |
| CN110383066B (zh) | 2016-12-09 | 2023-03-31 | 戴纳立制药公司 | 化合物、组合物和方法 |
| AU2023206890A1 (en) | 2022-01-12 | 2024-08-22 | Denali Therapeutics Inc. | Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5206235A (en) * | 1991-03-20 | 1993-04-27 | Merck & Co., Inc. | Benzo-fused lactams that promote the release of growth hormone |
| US5583130A (en) * | 1992-09-25 | 1996-12-10 | Merck & Co., Inc. | Benzo-fused lactams promote release of growth hormone |
-
1995
- 1995-08-16 IL IL11495595A patent/IL114955A/xx active IP Right Grant
- 1995-08-17 CZ CZ97458A patent/CZ45897A3/cs unknown
- 1995-08-17 EP EP95927662A patent/EP0777668A1/en not_active Ceased
- 1995-08-17 CA CA002196877A patent/CA2196877A1/en not_active Abandoned
- 1995-08-17 WO PCT/DK1995/000332 patent/WO1996005195A1/en not_active Application Discontinuation
- 1995-08-17 PL PL95318633A patent/PL318633A1/xx unknown
- 1995-08-17 HU HU9701234A patent/HUT76645A/hu unknown
- 1995-08-17 ZA ZA956869A patent/ZA956869B/xx unknown
- 1995-08-17 JP JP8506935A patent/JPH10504293A/ja active Pending
- 1995-08-17 BR BR9508805A patent/BR9508805A/pt not_active Application Discontinuation
- 1995-08-17 CN CN95195133A patent/CN1158127A/zh active Pending
- 1995-08-17 AU AU31618/95A patent/AU697003B2/en not_active Ceased
- 1995-08-17 MX MX9701187A patent/MX9701187A/es unknown
- 1995-09-15 TW TW084109669A patent/TW321640B/zh active
-
1997
- 1997-01-29 US US08/790,133 patent/US5817654A/en not_active Expired - Fee Related
- 1997-02-14 NO NO970684A patent/NO970684L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL114955A0 (en) | 1995-12-08 |
| NO970684D0 (no) | 1997-02-14 |
| WO1996005195A1 (en) | 1996-02-22 |
| PL318633A1 (en) | 1997-06-23 |
| US5817654A (en) | 1998-10-06 |
| HUT76645A (en) | 1997-10-28 |
| JPH10504293A (ja) | 1998-04-28 |
| CA2196877A1 (en) | 1996-02-22 |
| EP0777668A1 (en) | 1997-06-11 |
| ZA956869B (en) | 1996-04-10 |
| MX9701187A (es) | 1997-05-31 |
| AU3161895A (en) | 1996-03-07 |
| IL114955A (en) | 1999-12-22 |
| AU697003B2 (en) | 1998-09-24 |
| NO970684L (no) | 1997-04-17 |
| BR9508805A (pt) | 1998-01-06 |
| CN1158127A (zh) | 1997-08-27 |
| TW321640B (no) | 1997-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0659179B1 (en) | Benzo-fused lactams promote release of growth hormone | |
| US5773441A (en) | 2-acylaminopropanamides as growth hormone secretagogues | |
| CZ45897A3 (en) | Novel n-substituted naphthocondensated lactams | |
| JPH0665215A (ja) | 新規なベンゾジアゼピン類似体 | |
| JPH069579A (ja) | 新しいベンゾジアゼピン類似体 | |
| JPH09508620A (ja) | 二環式フィブリノゲンアンタゴニスト | |
| EP0703222A1 (en) | 3-aminoazepine compound and pharmaceutical use thereof | |
| EP1060190B1 (en) | New salt forms of (2e)- 5-amino-5- methylhex-2- enoic acid n-methyl-n-((1r)-1-(n- methyl-n-((1r)-1-(methylcarbamoyl)-2- phenylethyl)carbamoyl)-2- (2-naphtyl)ethyl)amide | |
| JP2002518483A (ja) | β−アミロイドペプチド放出を阻害するための化合物および／またはその合成 | |
| JP2003510360A (ja) | インテグリン受容体拮抗薬 | |
| CN105492434A (zh) | Rorc2抑制剂及其使用方法 | |
| US20040106792A1 (en) | Biphenyl compound | |
| UA73530C2 (uk) | Сполука з властивостями вивільнювати гормон росту | |
| TWI710559B (zh) | 新吡啶陽離子化合物、包含該化合物的藥學組成物、其用途及其製備方法 | |
| JP2002518482A (ja) | β−アミロイドペプチド放出および／またはその合成を阻害する化合物 | |
| JPH0680649A (ja) | コレシストキニン拮抗剤 | |
| JP2000508666A (ja) | 成長ホルモン放出特性を有する化合物 | |
| KR100753005B1 (ko) | 1,5-벤조디아제핀 유도체 칼슘염 및 그의 제조법 및 이화합물을 유효 성분으로 하는 의약 | |
| JPH0680650A (ja) | コレシストキニン拮抗薬 | |
| JP2002542151A (ja) | 成長ホルモン分泌促進物質としての新規なアミド誘導体 | |
| EP1200432B1 (en) | Amido spiropiperidines promote the release of growth hormone | |
| GB2330834A (en) | Naphtho-fused lactams that stimulate release of growth hormone | |
| JPH06239750A (ja) | ５員及び６員複素環式環を有する１，４−ベンゾジアゼピン類 | |
| MXPA00008576A (es) | Nuevas formas salinas de la n-metil-n-( (1r)-1-(n-metil-n- ( (1r)-1-(metilcarbamoil)- 2-feniletil)carbamoil)-2- (2-naftil)etil)amida del acido (2e)-5-metilhex- 2-enoico | |
| CZ20003152A3 (cs) | Soli N-methyi-N-((lR)-l-(N-methyl-N-((lR)-l- (methylkarbamoyl)-2-fenylethyl)karbamoyl)-2 (2-naftyl)ethyl)amidu (2E)-5-amino-5-methylhex- 2-enové kyseliny |