CZ304379B6 - Proteiny obsahující konzervované oblasti povrchového antigenu NhhA z Neisseria meningitidis - Google Patents

Proteiny obsahující konzervované oblasti povrchového antigenu NhhA z Neisseria meningitidis Download PDF

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Publication number
CZ304379B6
CZ304379B6 CZ2002-2482A CZ20022482A CZ304379B6 CZ 304379 B6 CZ304379 B6 CZ 304379B6 CZ 20022482 A CZ20022482 A CZ 20022482A CZ 304379 B6 CZ304379 B6 CZ 304379B6
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CZ
Czechia
Prior art keywords
seq
thr
gly
residues
ala
Prior art date
Application number
CZ2002-2482A
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Czech (cs)
English (en)
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CZ20022482A3 (cs
Inventor
Ian Richard Anselm Peak
Michael Paul Jennings
Original Assignee
The University Of Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by The University Of Queensland filed Critical The University Of Queensland
Publication of CZ20022482A3 publication Critical patent/CZ20022482A3/cs
Publication of CZ304379B6 publication Critical patent/CZ304379B6/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CZ2002-2482A 2000-01-25 2001-01-25 Proteiny obsahující konzervované oblasti povrchového antigenu NhhA z Neisseria meningitidis CZ304379B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17791700P 2000-01-25 2000-01-25

Publications (2)

Publication Number Publication Date
CZ20022482A3 CZ20022482A3 (cs) 2003-01-15
CZ304379B6 true CZ304379B6 (cs) 2014-04-09

Family

ID=22650445

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ2002-2482A CZ304379B6 (cs) 2000-01-25 2001-01-25 Proteiny obsahující konzervované oblasti povrchového antigenu NhhA z Neisseria meningitidis

Country Status (18)

Country Link
US (4) US7947291B2 (de)
EP (2) EP1252182B1 (de)
JP (3) JP2003523208A (de)
KR (1) KR100698561B1 (de)
CN (2) CN1419564A (de)
AU (1) AU2818101A (de)
BR (1) BR0107857A (de)
CA (1) CA2398139A1 (de)
CZ (1) CZ304379B6 (de)
ES (1) ES2389719T3 (de)
HU (1) HUP0300696A3 (de)
IL (2) IL150822A0 (de)
MX (1) MXPA02007184A (de)
NO (1) NO332229B1 (de)
NZ (1) NZ520445A (de)
PL (1) PL216780B1 (de)
WO (1) WO2001055182A1 (de)
ZA (1) ZA200206153B (de)

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BR9910089A (pt) 1998-05-01 2004-06-08 Chiron Corp Composições e antìgenos de neisseria meningitidis
ES2397918T3 (es) * 1999-04-30 2013-03-12 Novartis Vaccines And Diagnostics S.R.L. Antígenos Neisseriales conservados
CN100338218C (zh) * 1999-05-19 2007-09-19 启龙股份公司 组合式奈瑟球菌组合物
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
CN1419564A (zh) * 2000-01-25 2003-05-21 昆士兰大学 包含脑膜炎奈瑟氏球菌表面抗原NhhA的保守区域的蛋白质
EP2270030B1 (de) * 2000-02-28 2012-05-23 Novartis Vaccines and Diagnostics S.r.l. Heterologe Expression Neisserscher Proteine
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
GB0220199D0 (en) * 2002-08-30 2002-10-09 Univ Utrecht Mutant protein and refolding method
TWI360424B (en) * 2002-08-02 2012-03-21 Glaxosmithkline Biolog Sa Vaccine
PT1549338E (pt) 2002-10-11 2011-02-23 Novartis Vaccines & Diagnostic Vacinas polipeptídicas para protecção alargada contra linhagens meningocócicas hipervirulentas
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
WO2007042326A2 (en) * 2005-10-14 2007-04-19 Intercell Ag Neisseria meningitidis antigens
JP5275983B2 (ja) 2006-06-12 2013-08-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
JP2012512240A (ja) 2008-12-17 2012-05-31 ノバルティス アーゲー ヘモグロビン受容体を含む髄膜炎菌ワクチン
US20120070458A1 (en) 2009-03-24 2012-03-22 Novartis Ag Adjuvanting meningococcal factor h binding protein
WO2010109324A1 (en) 2009-03-24 2010-09-30 Novartis Ag Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
WO2011024071A1 (en) 2009-08-27 2011-03-03 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
NZ622048A (en) 2009-08-27 2015-10-30 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
BR112012010531A2 (pt) 2009-10-27 2019-09-24 Novartis Ag "polipeptídeos de modificação meningocócica fhbp"
EP2544713A1 (de) 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Immunogene zusammensetzung
JP2013522177A (ja) 2010-03-11 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム グラム陰性細菌性、例えば髄膜炎菌性の感染または疾患に対する免疫原性組成物またはワクチン
CN102802662A (zh) 2010-03-18 2012-11-28 诺华有限公司 用于脑膜炎球菌血清组b的含佐剂疫苗
AU2011268507B2 (en) 2010-06-25 2014-08-14 Novartis Ag Combinations of meningococcal factor H binding proteins
EP2598521A4 (de) * 2010-07-30 2014-03-19 Univ Griffith Rekombinante neisseria-meningitidis-por-a-porin-proteine
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
WO2012032498A2 (en) 2010-09-10 2012-03-15 Novartis Ag Developments in meningococcal outer membrane vesicles
WO2012054879A1 (en) * 2010-10-22 2012-04-26 Duke University Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia
US20150147356A1 (en) 2011-05-12 2015-05-28 Alan Kimura Antipyretics to enhance tolerability of vesicle-based vaccines
CA2862247A1 (en) 2011-12-29 2013-07-04 Novartis Ag Adjuvanted combinations of meningococcal factor h binding proteins
AU2013214105A1 (en) 2012-02-02 2014-07-24 Novartis Ag Promoters for increased protein expression in meningococcus
ES2750366T3 (es) 2012-03-08 2020-03-25 Glaxosmithkline Biologicals Sa Ensayo de potencia in vitro para vacunas meningocócicas basadas en proteína
CN104602704B (zh) 2012-06-14 2019-08-06 诺华股份有限公司 针对血清组x脑膜炎球菌的疫苗
CA2882619A1 (en) 2012-09-06 2014-03-13 Novartis Ag Combination vaccines with serogroup b meningococcus and d/t/p
SG11201606478YA (en) 2014-02-28 2016-09-29 Glaxosmithkline Biolog Sa Modified meningococcal fhbp polypeptides
CN110214022A (zh) 2016-11-25 2019-09-06 葛兰素史密丝克莱恩生物有限公司 免疫原性缀合物及其用途
BR112019010625A2 (pt) 2016-11-25 2019-10-22 Glaxosmithkline Biologicals Sa conjugado imunogênico, processo para preparar o conjugado imunogênico, nomv-ligante intermediário, usos do mesmo e de nomv, composição imunogênica, e, vacina.
WO2024178355A1 (en) * 2023-02-24 2024-08-29 BioNTech SE Systems and methods for engineering synthetic antigens to promote tailored immune responses

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO1999031132A1 (en) * 1997-12-12 1999-06-24 The University Of Queensland NOVEL SURFACE PROTEIN OF $i(NEISSERIA MENINGITIDIS)
WO1999036544A2 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
WO1999058683A2 (en) * 1998-05-13 1999-11-18 Smithkline Beecham Biologicals S.A. BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS)

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TWI360424B (en) * 2002-08-02 2012-03-21 Glaxosmithkline Biolog Sa Vaccine
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WO1999031132A1 (en) * 1997-12-12 1999-06-24 The University Of Queensland NOVEL SURFACE PROTEIN OF $i(NEISSERIA MENINGITIDIS)
WO1999036544A2 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
WO1999058683A2 (en) * 1998-05-13 1999-11-18 Smithkline Beecham Biologicals S.A. BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS)

Also Published As

Publication number Publication date
JP2012051902A (ja) 2012-03-15
KR100698561B1 (ko) 2007-03-21
PL356819A1 (en) 2004-07-12
BR0107857A (pt) 2002-10-29
US20090068216A1 (en) 2009-03-12
NO20023487D0 (no) 2002-07-22
EP2395013A3 (de) 2012-03-21
NZ520445A (en) 2004-02-27
EP1252182A1 (de) 2002-10-30
US8367070B2 (en) 2013-02-05
EP1252182A4 (de) 2005-03-02
NO332229B1 (no) 2012-08-06
KR20020065938A (ko) 2002-08-14
HUP0300696A2 (hu) 2003-07-28
US20020160016A1 (en) 2002-10-31
CN1419564A (zh) 2003-05-21
JP2014024849A (ja) 2014-02-06
ES2389719T3 (es) 2012-10-30
JP2003523208A (ja) 2003-08-05
US20090068229A1 (en) 2009-03-12
IL150822A0 (en) 2003-02-12
HUP0300696A3 (en) 2004-10-28
US7947291B2 (en) 2011-05-24
CN102417537A (zh) 2012-04-18
EP2395013A2 (de) 2011-12-14
US8383790B2 (en) 2013-02-26
IL150822A (en) 2011-06-30
PL216780B1 (pl) 2014-05-30
MXPA02007184A (es) 2004-02-26
NO20023487L (no) 2002-09-24
CZ20022482A3 (cs) 2003-01-15
ZA200206153B (en) 2003-11-03
EP1252182B1 (de) 2012-06-20
AU2818101A (en) 2001-08-07
CA2398139A1 (en) 2001-08-02
WO2001055182A1 (en) 2001-08-02
US20130136762A1 (en) 2013-05-30

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MM4A Patent lapsed due to non-payment of fee

Effective date: 20010125