HUP0300696A2 - A Neisseria meningitidis NhhA felületi antigén állandó régióit tartalmazó proteinek - Google Patents

A Neisseria meningitidis NhhA felületi antigén állandó régióit tartalmazó proteinek

Info

Publication number
HUP0300696A2
HUP0300696A2 HU0300696A HUP0300696A HUP0300696A2 HU P0300696 A2 HUP0300696 A2 HU P0300696A2 HU 0300696 A HU0300696 A HU 0300696A HU P0300696 A HUP0300696 A HU P0300696A HU P0300696 A2 HUP0300696 A2 HU P0300696A2
Authority
HU
Hungary
Prior art keywords
nhha
isolated protein
proteins
surface antigen
neisseria meningitidis
Prior art date
Application number
HU0300696A
Other languages
English (en)
Inventor
Michael Paul Jennings
Ian Richard Anselm Peak
Original Assignee
The University Of Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Queensland filed Critical The University Of Queensland
Publication of HUP0300696A2 publication Critical patent/HUP0300696A2/hu
Publication of HUP0300696A3 publication Critical patent/HUP0300696A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány tárgya egy izolált protein, amely egy NhhA polipeptidbőltizenkét vagy több szomszédos, állandó aminosavat tartalmaz, amelyizolált protein olyan immunválaszt képes kiváltani, amily kevésbétörzs-specifikus, mint az, amelyet az NhhA polipeptid vált ki és azizolált protein nem vad típusú NhhA polipeptid. A találmány tárgyátképezi továbbá a fenti izolált proteint tartalmazó gyógyszerkészítményés az izolált proteint kódol, izolált nukleinsav. Ó
HU0300696A 2000-01-25 2001-01-25 Proteins comprising conserved regions of neisseria meningitidis surface antigen nhha HUP0300696A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17791700P 2000-01-25 2000-01-25
PCT/AU2001/000069 WO2001055182A1 (en) 2000-01-25 2001-01-25 PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA

Publications (2)

Publication Number Publication Date
HUP0300696A2 true HUP0300696A2 (hu) 2003-07-28
HUP0300696A3 HUP0300696A3 (en) 2004-10-28

Family

ID=22650445

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0300696A HUP0300696A3 (en) 2000-01-25 2001-01-25 Proteins comprising conserved regions of neisseria meningitidis surface antigen nhha

Country Status (18)

Country Link
US (4) US7947291B2 (hu)
EP (2) EP1252182B1 (hu)
JP (3) JP2003523208A (hu)
KR (1) KR100698561B1 (hu)
CN (2) CN102417537A (hu)
AU (1) AU2818101A (hu)
BR (1) BR0107857A (hu)
CA (1) CA2398139A1 (hu)
CZ (1) CZ304379B6 (hu)
ES (1) ES2389719T3 (hu)
HU (1) HUP0300696A3 (hu)
IL (2) IL150822A0 (hu)
MX (1) MXPA02007184A (hu)
NO (1) NO332229B1 (hu)
NZ (1) NZ520445A (hu)
PL (1) PL216780B1 (hu)
WO (1) WO2001055182A1 (hu)
ZA (1) ZA200206153B (hu)

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WO2001055182A1 (en) * 2000-01-25 2001-08-02 The University Of Queensland PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA
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EP2353608B1 (en) 2002-10-11 2019-12-18 Novartis Vaccines and Diagnostics S.r.l. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
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CN102802662A (zh) 2010-03-18 2012-11-28 诺华有限公司 用于脑膜炎球菌血清组b的含佐剂疫苗
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
CA2806613A1 (en) * 2010-07-30 2012-02-02 Griffith University Recombinant neisseria meningitidis pora porin proteins
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
ES2759484T3 (es) 2010-09-10 2020-05-11 Glaxosmithkline Biologicals Sa Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo
WO2012054879A1 (en) * 2010-10-22 2012-04-26 Duke University Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia
EP2707009A1 (en) 2011-05-12 2014-03-19 Novartis AG Antipyretics to enhance tolerability of vesicle-based vaccines
US10596246B2 (en) 2011-12-29 2020-03-24 Glaxosmithkline Biological Sa Adjuvanted combinations of meningococcal factor H binding proteins
ES2654613T3 (es) 2012-02-02 2018-02-14 Glaxosmithkline Biologicals Sa Promotores para una expresión aumentada de proteínas en meningococos
ES2750366T3 (es) 2012-03-08 2020-03-25 Glaxosmithkline Biologicals Sa Ensayo de potencia in vitro para vacunas meningocócicas basadas en proteína
CA2876138C (en) 2012-06-14 2023-09-19 Novartis Ag Vaccines for serogroup x meningococcus
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Also Published As

Publication number Publication date
US20130136762A1 (en) 2013-05-30
ES2389719T3 (es) 2012-10-30
BR0107857A (pt) 2002-10-29
PL356819A1 (en) 2004-07-12
KR20020065938A (ko) 2002-08-14
US20090068216A1 (en) 2009-03-12
US8367070B2 (en) 2013-02-05
CZ304379B6 (cs) 2014-04-09
PL216780B1 (pl) 2014-05-30
ZA200206153B (en) 2003-11-03
US20020160016A1 (en) 2002-10-31
IL150822A0 (en) 2003-02-12
WO2001055182A1 (en) 2001-08-02
JP2012051902A (ja) 2012-03-15
EP2395013A3 (en) 2012-03-21
AU2818101A (en) 2001-08-07
IL150822A (en) 2011-06-30
NO20023487D0 (no) 2002-07-22
EP1252182B1 (en) 2012-06-20
EP1252182A1 (en) 2002-10-30
KR100698561B1 (ko) 2007-03-21
US7947291B2 (en) 2011-05-24
JP2014024849A (ja) 2014-02-06
CN1419564A (zh) 2003-05-21
EP2395013A2 (en) 2011-12-14
CZ20022482A3 (cs) 2003-01-15
CN102417537A (zh) 2012-04-18
MXPA02007184A (es) 2004-02-26
HUP0300696A3 (en) 2004-10-28
US20090068229A1 (en) 2009-03-12
NO332229B1 (no) 2012-08-06
JP2003523208A (ja) 2003-08-05
EP1252182A4 (en) 2005-03-02
NZ520445A (en) 2004-02-27
CA2398139A1 (en) 2001-08-02
US8383790B2 (en) 2013-02-26
NO20023487L (no) 2002-09-24

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