HUP0401611A2 - Glikozil-foszfatidil-inozitolt tartalmazó kiméra polipeptidek - Google Patents

Glikozil-foszfatidil-inozitolt tartalmazó kiméra polipeptidek

Info

Publication number
HUP0401611A2
HUP0401611A2 HU0401611A HUP0401611A HUP0401611A2 HU P0401611 A2 HUP0401611 A2 HU P0401611A2 HU 0401611 A HU0401611 A HU 0401611A HU P0401611 A HUP0401611 A HU P0401611A HU P0401611 A2 HUP0401611 A2 HU P0401611A2
Authority
HU
Hungary
Prior art keywords
polypeptides
glycosylphosphatidylinositol
containing polypeptides
domain
gpi
Prior art date
Application number
HU0401611A
Other languages
English (en)
Inventor
Richard Ross
Original Assignee
Asterion Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0124620A external-priority patent/GB2380735A/en
Priority claimed from GB0200904A external-priority patent/GB0200904D0/en
Priority claimed from GB0218889A external-priority patent/GB0218889D0/en
Application filed by Asterion Limited filed Critical Asterion Limited
Publication of HUP0401611A2 publication Critical patent/HUP0401611A2/hu
Publication of HUP0401611A3 publication Critical patent/HUP0401611A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)

Abstract

A találmány tárgyát olyan polipeptidek képezik, amelyek citokinreceptorkötő doménját és egy olyan domént tartalmaznak, amelyglikozil-foszfatidil-inozitol (GPI) horgonyok kapcsolódására szolgálószignálszekvenciát tartalmaz. A találmány tárgyát képezik továbbáeljárások a polipeptidek gyártására, a polipeptideket kódolónukleinsav-molekulák és a polipeptideket tartalmazó terápiáskészítmények. Ó
HU0401611A 2001-10-13 2002-10-11 Glycosylphosphatidylinositol containing polypeptides HUP0401611A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0124620A GB2380735A (en) 2001-10-13 2001-10-13 GPI-anchored proteins
GB0200904A GB0200904D0 (en) 2002-01-16 2002-01-16 Anchors-2
GB0218889A GB0218889D0 (en) 2002-08-14 2002-08-14 Anchors 3
PCT/GB2002/004665 WO2003034275A2 (en) 2001-10-13 2002-10-11 Chimeric glycosylphosphatidylinositol containing peptides

Publications (2)

Publication Number Publication Date
HUP0401611A2 true HUP0401611A2 (hu) 2004-11-29
HUP0401611A3 HUP0401611A3 (en) 2010-01-28

Family

ID=27256298

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401611A HUP0401611A3 (en) 2001-10-13 2002-10-11 Glycosylphosphatidylinositol containing polypeptides

Country Status (17)

Country Link
US (1) US7485713B2 (hu)
EP (1) EP1446733B1 (hu)
JP (1) JP4384492B2 (hu)
KR (2) KR20100039911A (hu)
CN (1) CN1568330A (hu)
AT (1) ATE442444T1 (hu)
AU (1) AU2002334161B2 (hu)
CA (1) CA2494706A1 (hu)
DE (1) DE60233674D1 (hu)
DK (1) DK1446733T3 (hu)
ES (1) ES2329228T3 (hu)
HU (1) HUP0401611A3 (hu)
IL (1) IL161296A0 (hu)
NZ (1) NZ532460A (hu)
PL (1) PL369953A1 (hu)
PT (1) PT1446733E (hu)
WO (1) WO2003034275A2 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080073293A (ko) 2005-10-14 2008-08-08 메디뮨 엘엘씨 항체 라이브러리의 세포 디스플레이
ES2526079T3 (es) * 2005-12-20 2015-01-05 Sbi Biotech Co., Ltd. Anticuerpo anti-ILT7
WO2007098547A1 (en) * 2006-03-01 2007-09-07 Apollo Life Sciences Limited A molecule and chimeric molecules thereof
GB0618082D0 (en) * 2006-09-14 2006-10-25 Asterion Ltd Growth factor
WO2008100816A2 (en) * 2007-02-09 2008-08-21 Medimmune, Llc Antibody libray display by yeast cell plasma membrane
CN103694337B (zh) * 2008-02-08 2016-03-02 Ambrx公司 经修饰瘦素多肽和其用途
JP6542197B2 (ja) 2013-04-12 2019-07-10 エヴォックス・セラピューティクス・リミテッド 治療的送達小胞

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374548A (en) * 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
US4857637A (en) * 1986-05-07 1989-08-15 Genentech, Inc. Methods and compositions for immunologically modulating growth hormone receptor activity
US5057417A (en) * 1987-06-12 1991-10-15 Genentech, Inc. Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
US6113917A (en) * 1995-04-25 2000-09-05 Rmf Dictagene S.A. Modified polypeptides for enhanced immunogenicity
TW562807B (en) * 1997-04-01 2003-11-21 Chugai Pharmaceutical Co Ltd Novel secretory membrane protein
CA2294704A1 (en) * 1997-06-26 1999-01-07 Immunex Corporation Protein that binds trail
EP1081224B1 (en) * 1998-05-20 2006-06-07 Chugai Seiyaku Kabushiki Kaisha Novel method for cloning a gene
JP2002542771A (ja) * 1999-03-24 2002-12-17 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒト腫瘍壊死因子レセプターｔｒ９
JP3815409B2 (ja) * 2002-08-29 2006-08-30 ブラザー工業株式会社 電話端末、通話システムおよび端末制御プログラム

Also Published As

Publication number Publication date
NZ532460A (en) 2005-10-28
EP1446733B1 (en) 2009-09-09
PL369953A1 (en) 2005-05-02
JP4384492B2 (ja) 2009-12-16
JP2005505307A (ja) 2005-02-24
AU2002334161B2 (en) 2007-03-29
WO2003034275A3 (en) 2003-11-27
DE60233674D1 (de) 2009-10-22
CA2494706A1 (en) 2003-04-24
EP1446733A2 (en) 2004-08-18
KR20100039911A (ko) 2010-04-16
US20050059577A1 (en) 2005-03-17
DK1446733T3 (da) 2009-10-26
KR20050035511A (ko) 2005-04-18
ATE442444T1 (de) 2009-09-15
CN1568330A (zh) 2005-01-19
WO2003034275A2 (en) 2003-04-24
PT1446733E (pt) 2009-09-28
HUP0401611A3 (en) 2010-01-28
ES2329228T3 (es) 2009-11-24
IL161296A0 (en) 2004-09-27
US7485713B2 (en) 2009-02-03

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees