SG11201606478YA - Modified meningococcal fhbp polypeptides - Google Patents

Modified meningococcal fhbp polypeptides

Info

Publication number
SG11201606478YA
SG11201606478YA SG11201606478YA SG11201606478YA SG11201606478YA SG 11201606478Y A SG11201606478Y A SG 11201606478YA SG 11201606478Y A SG11201606478Y A SG 11201606478YA SG 11201606478Y A SG11201606478Y A SG 11201606478YA SG 11201606478Y A SG11201606478Y A SG 11201606478YA
Authority
SG
Singapore
Prior art keywords
meningococcal fhbp
fhbp polypeptides
modified meningococcal
modified
polypeptides
Prior art date
Application number
SG11201606478YA
Inventor
Matthew Bottomley
Enrico Malito
Manuele Martinelli
Maria Scarselli
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of SG11201606478YA publication Critical patent/SG11201606478YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/101Plasmid DNA for bacteria
SG11201606478YA 2014-02-28 2015-02-27 Modified meningococcal fhbp polypeptides SG11201606478YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14157399 2014-02-28
EP14177566 2014-07-17
PCT/EP2015/054174 WO2015128480A1 (en) 2014-02-28 2015-02-27 Modified meningococcal fhbp polypeptides

Publications (1)

Publication Number Publication Date
SG11201606478YA true SG11201606478YA (en) 2016-09-29

Family

ID=52596977

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201606478YA SG11201606478YA (en) 2014-02-28 2015-02-27 Modified meningococcal fhbp polypeptides
SG10201907875TA SG10201907875TA (en) 2014-02-28 2015-02-27 Modified meningococcal fhbp polypeptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201907875TA SG10201907875TA (en) 2014-02-28 2015-02-27 Modified meningococcal fhbp polypeptides

Country Status (23)

Country Link
US (3) US10392424B2 (en)
EP (2) EP3110442B1 (en)
JP (3) JP6786394B2 (en)
KR (2) KR20160127104A (en)
CN (1) CN106661092B (en)
AU (2) AU2015222121B2 (en)
BR (1) BR112016019735A2 (en)
CA (1) CA2940447C (en)
CY (1) CY1123622T1 (en)
DK (1) DK3110442T3 (en)
EA (1) EA034954B1 (en)
ES (1) ES2841378T3 (en)
HR (1) HRP20202080T1 (en)
HU (1) HUE052293T2 (en)
IL (1) IL247125B (en)
LT (1) LT3110442T (en)
MX (2) MX2016011176A (en)
PL (1) PL3110442T3 (en)
RS (1) RS61246B1 (en)
SG (2) SG11201606478YA (en)
SI (1) SI3110442T1 (en)
WO (1) WO2015128480A1 (en)
ZA (1) ZA201605534B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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DK3110442T3 (en) 2014-02-28 2020-12-14 Glaxosmithkline Biologicals Sa MODIFIED MENINGOKOK-FHBP POLYPEPTIDER
BE1022641B1 (en) 2014-07-17 2016-06-23 Glaxosmithkline Biologicals Sa MENINGOCOCCAL POLYPEPTIDES fHbp MODIFIED
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IL303108B1 (en) * 2017-01-31 2024-03-01 Pfizer Neisseria meningitidis compositions and methods thereof
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
CA3131741A1 (en) 2019-03-08 2020-09-17 Glaxosmithkline Biologicals Sa Carbocyclic derivatives and conjugated derivatives thereof, and their use in vaccines
GB202013262D0 (en) 2020-08-25 2020-10-07 Glaxosmithkline Biologicals Sa Vaccine Composition
WO2022178196A1 (en) 2021-02-19 2022-08-25 Sanofi Pasteur Inc. Meningococcal b recombinant vaccine
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods
GB202208089D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
GB202208093D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2024030931A1 (en) 2022-08-03 2024-02-08 Sanofi Pasteur Inc. Adjuvanted immunogenic composition against neisseria meningitidis b

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Also Published As

Publication number Publication date
WO2015128480A1 (en) 2015-09-03
CN106661092A (en) 2017-05-10
HRP20202080T1 (en) 2021-02-19
US20170008933A1 (en) 2017-01-12
BR112016019735A2 (en) 2017-10-17
MX2020004419A (en) 2020-07-29
JP2021019629A (en) 2021-02-18
EP3110442B1 (en) 2020-10-14
CA2940447C (en) 2023-07-11
CY1123622T1 (en) 2022-03-24
CN106661092B (en) 2021-07-06
DK3110442T3 (en) 2020-12-14
US20190315812A1 (en) 2019-10-17
SG10201907875TA (en) 2019-09-27
EP3110442A1 (en) 2017-01-04
AU2015222121B2 (en) 2018-01-18
SI3110442T1 (en) 2021-01-29
EA201691429A1 (en) 2017-02-28
ES2841378T3 (en) 2021-07-08
AU2015222121A1 (en) 2016-10-13
US11021522B2 (en) 2021-06-01
EP3782643A1 (en) 2021-02-24
HUE052293T2 (en) 2021-04-28
JP2017512060A (en) 2017-05-18
MX2016011176A (en) 2017-02-23
EA034954B1 (en) 2020-04-10
JP2022177111A (en) 2022-11-30
LT3110442T (en) 2020-12-28
ZA201605534B (en) 2022-05-25
AU2018202431A1 (en) 2018-04-26
CA2940447A1 (en) 2015-09-03
US20210253647A1 (en) 2021-08-19
US11932671B2 (en) 2024-03-19
US10392424B2 (en) 2019-08-27
KR20230035455A (en) 2023-03-13
JP6786394B2 (en) 2020-11-18
IL247125B (en) 2021-12-01
RS61246B1 (en) 2021-01-29
KR20160127104A (en) 2016-11-02
IL247125A0 (en) 2016-09-29
PL3110442T3 (en) 2021-04-19

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