IL150822A0 - PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA - Google Patents

PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA

Info

Publication number
IL150822A0
IL150822A0 IL15082201A IL15082201A IL150822A0 IL 150822 A0 IL150822 A0 IL 150822A0 IL 15082201 A IL15082201 A IL 15082201A IL 15082201 A IL15082201 A IL 15082201A IL 150822 A0 IL150822 A0 IL 150822A0
Authority
IL
Israel
Prior art keywords
nhha
proteins
surface antigen
neisseria meningitidis
conserved regions
Prior art date
Application number
IL15082201A
Other languages
English (en)
Original Assignee
Univ Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Queensland filed Critical Univ Queensland
Publication of IL150822A0 publication Critical patent/IL150822A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL15082201A 2000-01-25 2001-01-25 PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA IL150822A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17791700P 2000-01-25 2000-01-25
PCT/AU2001/000069 WO2001055182A1 (en) 2000-01-25 2001-01-25 PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA

Publications (1)

Publication Number Publication Date
IL150822A0 true IL150822A0 (en) 2003-02-12

Family

ID=22650445

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15082201A IL150822A0 (en) 2000-01-25 2001-01-25 PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA
IL150822A IL150822A (en) 2000-01-25 2002-07-18 Proteins Containing Preserved Areas of Meningitis Nisaria NhhA Area Antigens for Use as a Vaccine Against Multiple Strains of Meningitis Nisaria

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL150822A IL150822A (en) 2000-01-25 2002-07-18 Proteins Containing Preserved Areas of Meningitis Nisaria NhhA Area Antigens for Use as a Vaccine Against Multiple Strains of Meningitis Nisaria

Country Status (18)

Country Link
US (4) US7947291B2 (de)
EP (2) EP1252182B1 (de)
JP (3) JP2003523208A (de)
KR (1) KR100698561B1 (de)
CN (2) CN102417537A (de)
AU (1) AU2818101A (de)
BR (1) BR0107857A (de)
CA (1) CA2398139A1 (de)
CZ (1) CZ304379B6 (de)
ES (1) ES2389719T3 (de)
HU (1) HUP0300696A3 (de)
IL (2) IL150822A0 (de)
MX (1) MXPA02007184A (de)
NO (1) NO332229B1 (de)
NZ (1) NZ520445A (de)
PL (1) PL216780B1 (de)
WO (1) WO2001055182A1 (de)
ZA (1) ZA200206153B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9906927A (pt) * 1998-01-14 2001-11-20 Chiron Spa Proteìnas de neisseria meningitidis
NZ541361A (en) 1998-05-01 2008-04-30 Inst Genomic Research Neisseria meningitidis antigens and compositions relating to SEQ ID Nos:2916, 2918 and 2920
MXPA01010924A (es) * 1999-04-30 2002-05-06 Chiron Spa Antigenos de neisseria conservados.
NZ545647A (en) * 1999-05-19 2008-02-29 Chiron Srl Combination neisserial compositions
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
CN102417537A (zh) * 2000-01-25 2012-04-18 昆士兰大学 包含脑膜炎奈瑟氏球菌表面抗原NhhA的保守区域的蛋白质
BR0108711A (pt) 2000-02-28 2004-06-22 Chiron Spa Expressão heteróloga de proteìnas de neisseria
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
SI2255826T1 (sl) 2002-08-02 2016-07-29 Glaxosmithkline Biologicals S.A. Neisserijski vakcinski sestavki, ki obsegajo kombinacijo antigenov
GB0220199D0 (en) * 2002-08-30 2002-10-09 Univ Utrecht Mutant protein and refolding method
SI1549338T1 (sl) 2002-10-11 2011-04-29 Novartis Vaccines & Diagnostic Polipeptidna cepiva za ĺ iroko zaĺ äśito pred hipervirulentnimi miningokoknimi rodovi
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
EP1943269A2 (de) * 2005-10-14 2008-07-16 Intercell AG Neisseria-meningitidis-antigene
ES2337309T5 (es) 2006-06-12 2013-07-30 Glaxosmithkline Biologicals S.A. Vacuna
JP2012512240A (ja) 2008-12-17 2012-05-31 ノバルティス アーゲー ヘモグロビン受容体を含む髄膜炎菌ワクチン
WO2010109324A1 (en) 2009-03-24 2010-09-30 Novartis Ag Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
HUE049695T2 (hu) 2009-03-24 2020-10-28 Glaxosmithkline Biologicals Sa Adjuváló H meningococcus faktort kötõ fehérje
EP2470205A1 (de) 2009-08-27 2012-07-04 Novartis AG Hilfsstoff mit aluminium, oligonukleotid und polykation
CA2772104A1 (en) 2009-08-27 2011-03-03 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
EP2483390A2 (de) 2009-09-30 2012-08-08 Novartis AG Expression von meningokokken-fhbp-polypeptiden
BR112012010531A2 (pt) 2009-10-27 2019-09-24 Novartis Ag "polipeptídeos de modificação meningocócica fhbp"
JP2013521770A (ja) 2010-03-10 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン組成物
CA2792691A1 (en) 2010-03-11 2011-09-15 Glaxosmithkline Biologicals S.A. Immunogenic composition or vaccine against gram-negative bacterial, for example, neisserial, infection or disease
JP2013522287A (ja) 2010-03-18 2013-06-13 ノバルティス アーゲー 血清群ｂ髄膜炎菌のためのアジュバント添加ワクチン
CA2803239A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
CN103189387A (zh) * 2010-07-30 2013-07-03 格里菲斯大学 重组脑膜炎奈瑟氏菌PorA孔蛋白
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
BR112013005626B1 (pt) 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
WO2012054879A1 (en) * 2010-10-22 2012-04-26 Duke University Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia
US20150147356A1 (en) 2011-05-12 2015-05-28 Alan Kimura Antipyretics to enhance tolerability of vesicle-based vaccines
JP2015505309A (ja) 2011-12-29 2015-02-19 ノバルティス アーゲー 髄膜炎菌ｈ因子結合タンパク質のアジュバントされた組み合わせ
BR112014019166A2 (pt) 2012-02-02 2017-07-04 Novartis Ag promotores para expressão aumentada de proteína em meningococos
WO2013132040A2 (en) 2012-03-08 2013-09-12 Novartis Ag In vitro potency assay for protein-based meningococcal vaccines
CA2876138C (en) 2012-06-14 2023-09-19 Novartis Ag Vaccines for serogroup x meningococcus
EP2892553A1 (de) 2012-09-06 2015-07-15 Novartis AG Kombinationsvakzine mit serogruppe-b-meningokokken und d/t/p
HUE052293T2 (hu) 2014-02-28 2021-04-28 Glaxosmithkline Biologicals Sa Módosított fHbp meningococcus-polipeptidek
CN110214022A (zh) 2016-11-25 2019-09-06 葛兰素史密丝克莱恩生物有限公司 免疫原性缀合物及其用途
SI3544637T1 (sl) 2016-11-25 2021-02-26 Glaxosmithkline Biologicals S.A. Nativni OMV-antigen konjugati in njihova uporaba

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4550081A (en) 1980-05-19 1985-10-29 The Board Of Trustees Of The Leland Stanford Jr. University Non-reverting salmonella
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
EP0273116A3 (de) * 1986-10-09 1990-05-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Gonokokken- und Meningokokken-Polypeptide, Impfstoffe und Diagnostiken
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
US5144847A (en) 1988-03-24 1992-09-08 Johann Zach Pressure or force measuring device
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
EP0542874A4 (en) 1990-07-25 1994-05-11 Syngene Inc Circular extension for generating multiple nucleic acid complements
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5646259A (en) 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
DK0862656T3 (da) 1995-11-21 2001-04-09 Univ Yale Unimolekylær segmentamplifikation og -detektering
GB9611673D0 (en) 1996-06-05 1996-08-07 Peptide Therapeutics Ltd Meningococcal vaccine
CA2671261A1 (en) 1997-11-06 1999-05-20 Novartis Vaccines And Diagnostics S.R.L. Neisserial antigens
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
BR9906927A (pt) * 1998-01-14 2001-11-20 Chiron Spa Proteìnas de neisseria meningitidis
NZ541361A (en) 1998-05-01 2008-04-30 Inst Genomic Research Neisseria meningitidis antigens and compositions relating to SEQ ID Nos:2916, 2918 and 2920
GB9810276D0 (en) 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
WO2000061165A1 (en) 1999-04-13 2000-10-19 Smithkline Beecham Corporation Conserved adhesin motif and methods of use thereof
ES2323845T3 (es) * 1999-04-30 2009-07-27 Novartis Vaccines And Diagnostics, Inc. Secuencias genomicas de neisseria y procedimientos de uso.
MXPA01010924A (es) 1999-04-30 2002-05-06 Chiron Spa Antigenos de neisseria conservados.
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
CN102417537A (zh) * 2000-01-25 2012-04-18 昆士兰大学 包含脑膜炎奈瑟氏球菌表面抗原NhhA的保守区域的蛋白质
SI2255826T1 (sl) * 2002-08-02 2016-07-29 Glaxosmithkline Biologicals S.A. Neisserijski vakcinski sestavki, ki obsegajo kombinacijo antigenov
CA2550927A1 (en) * 2003-12-23 2005-07-14 Glaxosmithkline Biologicals S.A. A gram negative bacterium with reduced lps level in the outer membrane and use thereof for treating gram negative bacterial infection

Also Published As

Publication number Publication date
CA2398139A1 (en) 2001-08-02
JP2012051902A (ja) 2012-03-15
NO20023487L (no) 2002-09-24
EP2395013A3 (de) 2012-03-21
KR20020065938A (ko) 2002-08-14
US20090068229A1 (en) 2009-03-12
PL216780B1 (pl) 2014-05-30
US20130136762A1 (en) 2013-05-30
CZ304379B6 (cs) 2014-04-09
CN1419564A (zh) 2003-05-21
CN102417537A (zh) 2012-04-18
JP2003523208A (ja) 2003-08-05
HUP0300696A2 (hu) 2003-07-28
KR100698561B1 (ko) 2007-03-21
CZ20022482A3 (cs) 2003-01-15
ZA200206153B (en) 2003-11-03
US8383790B2 (en) 2013-02-26
PL356819A1 (en) 2004-07-12
NZ520445A (en) 2004-02-27
US7947291B2 (en) 2011-05-24
WO2001055182A1 (en) 2001-08-02
JP2014024849A (ja) 2014-02-06
NO20023487D0 (no) 2002-07-22
HUP0300696A3 (en) 2004-10-28
EP2395013A2 (de) 2011-12-14
EP1252182A4 (de) 2005-03-02
AU2818101A (en) 2001-08-07
EP1252182B1 (de) 2012-06-20
US8367070B2 (en) 2013-02-05
US20090068216A1 (en) 2009-03-12
BR0107857A (pt) 2002-10-29
MXPA02007184A (es) 2004-02-26
NO332229B1 (no) 2012-08-06
US20020160016A1 (en) 2002-10-31
EP1252182A1 (de) 2002-10-30
IL150822A (en) 2011-06-30
ES2389719T3 (es) 2012-10-30

Similar Documents

Publication Publication Date Title
HUP0300696A3 (en) Proteins comprising conserved regions of neisseria meningitidis surface antigen nhha
IL136684A0 (en) Novel surface protein of neisseria meningitidis
IL151942A0 (en) Compositions and methods for enhancing immunogenicity of antigens
CY2013025I1 (el) Ετερολογος εκφραση των πρωτεϊνων της neisseria
HUP0204250A3 (en) Use of hiv-protein or -polynucleotide for vaccine produce
CY2011001I1 (el) Εμβολια συνδυασμου για neisseria meningitidis
IL159894A0 (en) Therapeutic agents comprising pro-apoptotic proteins
IL212419A0 (en) Methods of administering anti-tnf antibodies
HK1041541A1 (zh) 鑑別使用人的靈活方法
TW479494U (en) Structure of pillow
HUP0300099A3 (en) Vaccine for the treatment of artherosclerosis
HK1056884A1 (en) Purification of hbv antigens for use in vaccines
HK1064024A1 (en) Combination for constructing intra-corporeal artificial kidney having function of metabolizing protein
PL367329A1 (en) Methods for reducing immunogenicity of polypeptides
FR2809615B3 (fr) Appareil electromecanique pour assurer le mouvement de flexion/extension des membres inferieurs chez les patients presentant une diminution des fonctions superieures
AU2001267613A1 (en) Adjuvant composition comprising FHA protein or fragment of FHA protein in free form
EP1452597A4 (de) Verfahren zur aktivierung von protein
TW567810U (en) Massage pillow
TW492296U (en) Multifunctional pillow for children
TW435705U (en) Glasses foot of eyeglasses
GB0031218D0 (en) Metgod of vaccine preparation
TW457913U (en) Construction of disposable pulp-molded pillow
TW435704U (en) Structure improvement of glasses foot for eyeglasses
GB0005728D0 (en) Conserved antigens
AUPR275901A0 (en) Improvements in design of pillows