CY2495B1 - Sulfonamides. - Google Patents

Sulfonamides.

Info

Publication number
CY2495B1
CY2495B1 CY0400089A CY0400089A CY2495B1 CY 2495 B1 CY2495 B1 CY 2495B1 CY 0400089 A CY0400089 A CY 0400089A CY 0400089 A CY0400089 A CY 0400089A CY 2495 B1 CY2495 B1 CY 2495B1
Authority
CY
Cyprus
Prior art keywords
pct
sec
compounds
date
endothelin
Prior art date
Application number
CY0400089A
Other languages
English (en)
Inventor
Volker Breu
Kaspar Burri
Jean-Marie Cassal
Martine Clozel
Georges Hirth
Bernd-Michael Loeffler
Marcel Mueller
Werner Neidhart
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CY2495B1 publication Critical patent/CY2495B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69—Benzenesulfonamido-pyrimidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Bipolar Transistors (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Lubricants (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
CY0400089A 1994-12-20 2004-12-14 Sulfonamides. CY2495B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH383794 1994-12-20
CH241995 1995-08-24

Publications (1)

Publication Number Publication Date
CY2495B1 true CY2495B1 (en) 2005-09-02

Family

ID=25690401

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400089A CY2495B1 (en) 1994-12-20 2004-12-14 Sulfonamides.

Country Status (26)

Country Link
US (1) US6004965A (lv)
EP (1) EP0799209B1 (lv)
JP (1) JP2989014B2 (lv)
KR (1) KR100445085B1 (lv)
CN (1) CN1098254C (lv)
AT (1) ATE246681T1 (lv)
AU (1) AU701767B2 (lv)
BR (1) BR9510104A (lv)
CA (1) CA2208018C (lv)
CY (1) CY2495B1 (lv)
CZ (1) CZ287916B6 (lv)
DE (1) DE69531457T2 (lv)
DK (1) DK0799209T3 (lv)
ES (1) ES2203649T3 (lv)
FI (1) FI120397B (lv)
HK (1) HK1001973A1 (lv)
HU (1) HU228619B1 (lv)
IL (1) IL116385A (lv)
MA (1) MA23744A1 (lv)
MY (1) MY131126A (lv)
NO (1) NO316645B1 (lv)
NZ (1) NZ297797A (lv)
PT (1) PT799209E (lv)
SA (1) SA95160421B1 (lv)
TW (1) TW313568B (lv)
WO (1) WO1996019459A1 (lv)

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US8168616B1 (en) 2000-11-17 2012-05-01 Novartis Ag Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
CA2431675C (en) 2000-12-18 2011-11-08 Actelion Pharmaceuticals Ltd. Novel sulfamides and their use as endothelin receptor antagonists
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
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US7371763B2 (en) 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
AU2003209119A1 (en) 2002-02-11 2003-09-04 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
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ES2378670T3 (es) 2002-02-11 2012-04-16 Bayer Healthcare, Llc Aril ureas como inhibidores de cinasas
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EA019661B1 (ru) 2006-12-08 2014-05-30 Лексикон Фармасьютикалз, Инк. Моноклональные антитела против angptl3
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TW270116B (lv) * 1991-04-25 1996-02-11 Hoffmann La Roche
RU2086544C1 (ru) * 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
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IL111959A (en) * 1993-12-17 2000-07-16 Tanabe Seiyaku Co N-(polysubstituted pyrimidin-4-yl) benzenesulfonamide derivatives their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES2203649T3 (es) 2004-04-16
NO972538L (no) 1997-06-04
SA95160421B1 (ar) 2006-05-01
DE69531457T2 (de) 2004-06-24
IL116385A (en) 2000-07-16
AU4304196A (en) 1996-07-10
AU701767B2 (en) 1999-02-04
MY131126A (en) 2007-07-31
DE69531457D1 (en) 2003-09-11
MX9704587A (es) 1998-07-31
NZ297797A (en) 1999-10-28
US6004965A (en) 1999-12-21
FI972628A (fi) 1997-06-18
JP2989014B2 (ja) 1999-12-13
HK1001973A1 (en) 1998-07-24
NO972538D0 (no) 1997-06-04
CZ287916B6 (cs) 2001-03-14
FI972628A0 (fi) 1997-06-18
CZ187497A3 (en) 1997-10-15
MA23744A1 (fr) 1996-07-01
ATE246681T1 (de) 2003-08-15
CA2208018A1 (en) 1996-06-27
PT799209E (pt) 2003-12-31
FI120397B (fi) 2009-10-15
DK0799209T3 (da) 2003-11-24
KR100445085B1 (ko) 2004-10-14
BR9510104A (pt) 1997-11-25
HUT77884A (hu) 1998-09-28
JPH10509182A (ja) 1998-09-08
EP0799209A1 (en) 1997-10-08
CN1098254C (zh) 2003-01-08
CA2208018C (en) 2007-03-27
NO316645B1 (no) 2004-03-22
EP0799209B1 (en) 2003-08-06
WO1996019459A1 (en) 1996-06-27
TW313568B (lv) 1997-08-21
CN1170407A (zh) 1998-01-14
HU228619B1 (en) 2013-04-29
IL116385A0 (en) 1996-03-31

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