CY2495B1 - Sulfonamides. - Google Patents

Sulfonamides.

Info

Publication number
CY2495B1
CY2495B1 CY0400089A CY0400089A CY2495B1 CY 2495 B1 CY2495 B1 CY 2495B1 CY 0400089 A CY0400089 A CY 0400089A CY 0400089 A CY0400089 A CY 0400089A CY 2495 B1 CY2495 B1 CY 2495B1
Authority
CY
Cyprus
Prior art keywords
pct
sec
compounds
date
endothelin
Prior art date
Application number
CY0400089A
Other languages
English (en)
Inventor
Volker Breu
Kaspar Burri
Jean-Marie Cassal
Martine Clozel
Georges Hirth
Bernd-Michael Loeffler
Marcel Mueller
Werner Neidhart
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CY2495B1 publication Critical patent/CY2495B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Bipolar Transistors (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Lubricants (AREA)
CY0400089A 1994-12-20 2004-12-14 Sulfonamides. CY2495B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH383794 1994-12-20
CH241995 1995-08-24

Publications (1)

Publication Number Publication Date
CY2495B1 true CY2495B1 (en) 2005-09-02

Family

ID=25690401

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400089A CY2495B1 (en) 1994-12-20 2004-12-14 Sulfonamides.

Country Status (25)

Country Link
US (1) US6004965A (cg-RX-API-DMAC7.html)
EP (1) EP0799209B1 (cg-RX-API-DMAC7.html)
JP (1) JP2989014B2 (cg-RX-API-DMAC7.html)
KR (1) KR100445085B1 (cg-RX-API-DMAC7.html)
CN (1) CN1098254C (cg-RX-API-DMAC7.html)
AT (1) ATE246681T1 (cg-RX-API-DMAC7.html)
AU (1) AU701767B2 (cg-RX-API-DMAC7.html)
BR (1) BR9510104A (cg-RX-API-DMAC7.html)
CA (1) CA2208018C (cg-RX-API-DMAC7.html)
CY (1) CY2495B1 (cg-RX-API-DMAC7.html)
CZ (1) CZ287916B6 (cg-RX-API-DMAC7.html)
DE (1) DE69531457T2 (cg-RX-API-DMAC7.html)
DK (1) DK0799209T3 (cg-RX-API-DMAC7.html)
ES (1) ES2203649T3 (cg-RX-API-DMAC7.html)
FI (1) FI120397B (cg-RX-API-DMAC7.html)
HU (1) HU228619B1 (cg-RX-API-DMAC7.html)
IL (1) IL116385A (cg-RX-API-DMAC7.html)
MA (1) MA23744A1 (cg-RX-API-DMAC7.html)
MY (1) MY131126A (cg-RX-API-DMAC7.html)
NO (1) NO316645B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ297797A (cg-RX-API-DMAC7.html)
PT (1) PT799209E (cg-RX-API-DMAC7.html)
SA (1) SA95160421B1 (cg-RX-API-DMAC7.html)
TW (1) TW313568B (cg-RX-API-DMAC7.html)
WO (1) WO1996019459A1 (cg-RX-API-DMAC7.html)

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US7371763B2 (en) 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
PT1478358E (pt) 2002-02-11 2013-09-11 Bayer Healthcare Llc Tosilato de sorafenib para o tratamento de doenças caracterizadas por angiogénese anormal
US20030216396A1 (en) 2002-02-11 2003-11-20 Bayer Corporation Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
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US20040002451A1 (en) 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
RU2329255C2 (ru) 2002-12-02 2008-07-20 Актелион Фармасьютиклз Лтд Пиримидинсульфамиды и их использование в качестве антагонистов эндотелиальных рецепторов
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
PL1626714T3 (pl) 2003-05-20 2007-12-31 Bayer Healthcare Llc Diarylowe pochodne mocznika do schorzeń, w których pośredniczy PDGFR
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IL111959A (en) * 1993-12-17 2000-07-16 Tanabe Seiyaku Co N-(polysubstituted pyrimidin-4-yl) benzenesulfonamide derivatives their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK0799209T3 (da) 2003-11-24
SA95160421B1 (ar) 2006-05-01
DE69531457T2 (de) 2004-06-24
DE69531457D1 (en) 2003-09-11
BR9510104A (pt) 1997-11-25
ES2203649T3 (es) 2004-04-16
WO1996019459A1 (en) 1996-06-27
KR100445085B1 (ko) 2004-10-14
EP0799209A1 (en) 1997-10-08
AU4304196A (en) 1996-07-10
CZ287916B6 (cs) 2001-03-14
FI972628A0 (fi) 1997-06-18
HU228619B1 (en) 2013-04-29
NZ297797A (en) 1999-10-28
HUT77884A (hu) 1998-09-28
NO972538D0 (no) 1997-06-04
CA2208018A1 (en) 1996-06-27
ATE246681T1 (de) 2003-08-15
NO972538L (no) 1997-06-04
JP2989014B2 (ja) 1999-12-13
IL116385A0 (en) 1996-03-31
US6004965A (en) 1999-12-21
NO316645B1 (no) 2004-03-22
CA2208018C (en) 2007-03-27
PT799209E (pt) 2003-12-31
CZ187497A3 (en) 1997-10-15
MX9704587A (es) 1998-07-31
HK1001973A1 (en) 1998-07-24
AU701767B2 (en) 1999-02-04
IL116385A (en) 2000-07-16
FI120397B (fi) 2009-10-15
TW313568B (cg-RX-API-DMAC7.html) 1997-08-21
MY131126A (en) 2007-07-31
JPH10509182A (ja) 1998-09-08
FI972628L (fi) 1997-06-18
EP0799209B1 (en) 2003-08-06
MA23744A1 (fr) 1996-07-01
CN1170407A (zh) 1998-01-14
CN1098254C (zh) 2003-01-08

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