CY2287B1 - Farnesyl transferase inhibiting 2-quinolone derivatives - Google Patents

Farnesyl transferase inhibiting 2-quinolone derivatives

Info

Publication number
CY2287B1
CY2287B1 CY0200044A CY0200044A CY2287B1 CY 2287 B1 CY2287 B1 CY 2287B1 CY 0200044 A CY0200044 A CY 0200044A CY 0200044 A CY0200044 A CY 0200044A CY 2287 B1 CY2287 B1 CY 2287B1
Authority
CY
Cyprus
Prior art keywords
farnesyl transferase
quinolone derivatives
transferase inhibiting
inhibiting
quinolone
Prior art date
Application number
CY0200044A
Other languages
English (en)
Inventor
David William Venet Marc G End
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CY2287B1 publication Critical patent/CY2287B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CY0200044A 1995-10-31 2002-07-15 Farnesyl transferase inhibiting 2-quinolone derivatives CY2287B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95202945 1995-10-31

Publications (1)

Publication Number Publication Date
CY2287B1 true CY2287B1 (en) 2003-07-04

Family

ID=8220785

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0200044A CY2287B1 (en) 1995-10-31 2002-07-15 Farnesyl transferase inhibiting 2-quinolone derivatives

Country Status (29)

Country Link
US (1) US5968952A (es)
EP (2) EP1019395B1 (es)
JP (1) JP4257869B2 (es)
KR (1) KR100417620B1 (es)
CN (1) CN1101391C (es)
AR (1) AR004699A1 (es)
AT (2) ATE212627T1 (es)
AU (1) AU712435B2 (es)
CA (1) CA2231143C (es)
CY (1) CY2287B1 (es)
CZ (1) CZ290954B6 (es)
DE (2) DE69618999T2 (es)
DK (1) DK1019395T3 (es)
EA (1) EA000719B1 (es)
ES (2) ES2171736T3 (es)
HK (2) HK1027576A1 (es)
HU (1) HU224032B1 (es)
IL (1) IL123567A (es)
MY (1) MY116577A (es)
NO (1) NO314037B1 (es)
NZ (1) NZ321576A (es)
PL (1) PL184168B1 (es)
PT (1) PT1019395E (es)
SI (1) SI1019395T1 (es)
SK (1) SK282642B6 (es)
TR (1) TR199800720T2 (es)
TW (1) TW349948B (es)
WO (1) WO1997016443A1 (es)
ZA (1) ZA969087B (es)

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Also Published As

Publication number Publication date
KR19990063639A (ko) 1999-07-26
SK282642B6 (sk) 2002-10-08
HK1027576A1 (en) 2001-01-19
PL184168B1 (pl) 2002-09-30
CZ127298A3 (cs) 1998-12-16
US5968952A (en) 1999-10-19
ES2171736T3 (es) 2002-09-16
AU712435B2 (en) 1999-11-04
AR004699A1 (es) 1999-03-10
CN1200732A (zh) 1998-12-02
HUP9802424A2 (hu) 1999-10-28
EP1106610B1 (en) 2004-06-16
JPH11514635A (ja) 1999-12-14
DE69618999D1 (de) 2002-03-14
IL123567A0 (en) 1998-10-30
SI1019395T1 (en) 2002-06-30
HUP9802424A3 (en) 2003-02-28
NO314037B1 (no) 2003-01-20
NO980928L (no) 1998-04-29
CZ290954B6 (cs) 2002-11-13
PL328230A1 (en) 1999-01-18
CA2231143A1 (en) 1997-05-09
EA000719B1 (ru) 2000-02-28
ZA969087B (en) 1998-04-29
IL123567A (en) 2002-11-10
DE69632751T2 (de) 2005-08-04
EP1019395B1 (en) 2002-01-30
MY116577A (en) 2004-02-28
TR199800720T2 (xx) 1998-09-21
MX9802067A (es) 1998-08-30
KR100417620B1 (ko) 2004-05-27
ATE269322T1 (de) 2004-07-15
ATE212627T1 (de) 2002-02-15
ES2233557T3 (es) 2005-06-16
EP1106610A1 (en) 2001-06-13
NZ321576A (en) 1999-05-28
DK1019395T3 (da) 2002-05-06
CN1101391C (zh) 2003-02-12
EA199800395A1 (ru) 1998-10-29
WO1997016443A1 (en) 1997-05-09
HU224032B1 (hu) 2005-05-30
DE69632751D1 (de) 2004-07-22
HK1036064A1 (en) 2001-12-21
PT1019395E (pt) 2002-07-31
CA2231143C (en) 2005-06-21
NO980928D0 (no) 1998-03-04
EP1019395A1 (en) 2000-07-19
AU7493396A (en) 1997-05-22
JP4257869B2 (ja) 2009-04-22
DE69618999T2 (de) 2002-09-26
SK55698A3 (en) 1999-02-11
TW349948B (en) 1999-01-11

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