DK1019395T3 - Farnesyltransferasehæmmende 2-quinolonderivater - Google Patents

Farnesyltransferasehæmmende 2-quinolonderivater

Info

Publication number
DK1019395T3
DK1019395T3 DK96937249T DK96937249T DK1019395T3 DK 1019395 T3 DK1019395 T3 DK 1019395T3 DK 96937249 T DK96937249 T DK 96937249T DK 96937249 T DK96937249 T DK 96937249T DK 1019395 T3 DK1019395 T3 DK 1019395T3
Authority
DK
Denmark
Prior art keywords
transferase inhibitor
farnesyl transferase
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
DK96937249T
Other languages
Danish (da)
English (en)
Inventor
David William End
Marc Gaston Venet
Patrick Rene Angibaud
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1019395T3 publication Critical patent/DK1019395T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK96937249T 1995-10-31 1996-10-25 Farnesyltransferasehæmmende 2-quinolonderivater DK1019395T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95202945 1995-10-31
PCT/EP1996/004661 WO1997016443A1 (en) 1995-10-31 1996-10-25 Farnesyl transferase inhibiting 2-quinolone derivatives

Publications (1)

Publication Number Publication Date
DK1019395T3 true DK1019395T3 (da) 2002-05-06

Family

ID=8220785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96937249T DK1019395T3 (da) 1995-10-31 1996-10-25 Farnesyltransferasehæmmende 2-quinolonderivater

Country Status (29)

Country Link
US (1) US5968952A (es)
EP (2) EP1019395B1 (es)
JP (1) JP4257869B2 (es)
KR (1) KR100417620B1 (es)
CN (1) CN1101391C (es)
AR (1) AR004699A1 (es)
AT (2) ATE212627T1 (es)
AU (1) AU712435B2 (es)
CA (1) CA2231143C (es)
CY (1) CY2287B1 (es)
CZ (1) CZ290954B6 (es)
DE (2) DE69632751T2 (es)
DK (1) DK1019395T3 (es)
EA (1) EA000719B1 (es)
ES (2) ES2233557T3 (es)
HK (2) HK1027576A1 (es)
HU (1) HU224032B1 (es)
IL (1) IL123567A (es)
MY (1) MY116577A (es)
NO (1) NO314037B1 (es)
NZ (1) NZ321576A (es)
PL (1) PL184168B1 (es)
PT (1) PT1019395E (es)
SI (1) SI1019395T1 (es)
SK (1) SK282642B6 (es)
TR (1) TR199800720T2 (es)
TW (1) TW349948B (es)
WO (1) WO1997016443A1 (es)
ZA (1) ZA969087B (es)

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Also Published As

Publication number Publication date
NO314037B1 (no) 2003-01-20
AR004699A1 (es) 1999-03-10
CZ127298A3 (cs) 1998-12-16
AU7493396A (en) 1997-05-22
KR19990063639A (ko) 1999-07-26
JPH11514635A (ja) 1999-12-14
DE69618999D1 (de) 2002-03-14
SI1019395T1 (en) 2002-06-30
KR100417620B1 (ko) 2004-05-27
EA000719B1 (ru) 2000-02-28
DE69632751D1 (de) 2004-07-22
NO980928D0 (no) 1998-03-04
NO980928L (no) 1998-04-29
ZA969087B (en) 1998-04-29
EP1106610A1 (en) 2001-06-13
ES2171736T3 (es) 2002-09-16
PL184168B1 (pl) 2002-09-30
HK1027576A1 (en) 2001-01-19
DE69632751T2 (de) 2005-08-04
ATE212627T1 (de) 2002-02-15
CY2287B1 (en) 2003-07-04
EP1106610B1 (en) 2004-06-16
NZ321576A (en) 1999-05-28
TW349948B (en) 1999-01-11
AU712435B2 (en) 1999-11-04
JP4257869B2 (ja) 2009-04-22
CZ290954B6 (cs) 2002-11-13
ATE269322T1 (de) 2004-07-15
TR199800720T2 (xx) 1998-09-21
IL123567A0 (en) 1998-10-30
CA2231143A1 (en) 1997-05-09
EP1019395A1 (en) 2000-07-19
HK1036064A1 (en) 2001-12-21
HUP9802424A2 (hu) 1999-10-28
SK282642B6 (sk) 2002-10-08
HU224032B1 (hu) 2005-05-30
CN1200732A (zh) 1998-12-02
EP1019395B1 (en) 2002-01-30
PL328230A1 (en) 1999-01-18
SK55698A3 (en) 1999-02-11
MY116577A (en) 2004-02-28
PT1019395E (pt) 2002-07-31
ES2233557T3 (es) 2005-06-16
MX9802067A (es) 1998-08-30
US5968952A (en) 1999-10-19
WO1997016443A1 (en) 1997-05-09
EA199800395A1 (ru) 1998-10-29
IL123567A (en) 2002-11-10
HUP9802424A3 (en) 2003-02-28
DE69618999T2 (de) 2002-09-26
CN1101391C (zh) 2003-02-12
CA2231143C (en) 2005-06-21

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