AU2001239275A1 - Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives - Google Patents
Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivativesInfo
- Publication number
- AU2001239275A1 AU2001239275A1 AU2001239275A AU3927501A AU2001239275A1 AU 2001239275 A1 AU2001239275 A1 AU 2001239275A1 AU 2001239275 A AU2001239275 A AU 2001239275A AU 3927501 A AU3927501 A AU 3927501A AU 2001239275 A1 AU2001239275 A1 AU 2001239275A1
- Authority
- AU
- Australia
- Prior art keywords
- protein transferase
- transferase inhibitor
- farnesyl protein
- podophyllotoxin derivatives
- inhibitor combinations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00200695 | 2000-02-29 | ||
EP00200695 | 2000-02-29 | ||
PCT/EP2001/002167 WO2001064198A2 (en) | 2000-02-29 | 2001-02-26 | Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001239275A1 true AU2001239275A1 (en) | 2001-09-12 |
Family
ID=8171114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001239275A Abandoned AU2001239275A1 (en) | 2000-02-29 | 2001-02-26 | Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1267871A2 (en) |
JP (1) | JP2003525238A (en) |
AU (1) | AU2001239275A1 (en) |
CA (1) | CA2397256A1 (en) |
WO (1) | WO2001064198A2 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2581125C (en) | 2004-09-22 | 2013-04-23 | Nippon Kayaku Kabushiki Kaisha | Modified poly(ethylene oxide-amino acid) copolymer, micelle preparation, and anticancer agent containing the same |
US20070213366A1 (en) | 2005-12-23 | 2007-09-13 | Justman Craig J | Treatment of Synucleinopathies |
US8323669B2 (en) | 2006-03-28 | 2012-12-04 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of taxane |
AU2007252678A1 (en) * | 2006-05-18 | 2007-11-29 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of podophyllotoxin |
JP5503872B2 (en) | 2006-11-06 | 2014-05-28 | 日本化薬株式会社 | Polymer derivatives of nucleic acid antimetabolites |
WO2008056654A1 (en) | 2006-11-08 | 2008-05-15 | Nippon Kayaku Kabushiki Kaisha | Polymeric derivative of nucleic acid metabolic antagonist |
CN101808651B (en) | 2007-09-28 | 2013-03-27 | 日本化药株式会社 | Polymer conjugate of steroid |
US8920788B2 (en) | 2008-03-18 | 2014-12-30 | Nippon Kayaku Kabushiki Kaisha | High-molecular weight conjugate of physiologically active substances |
JP5366940B2 (en) | 2008-05-08 | 2013-12-11 | 日本化薬株式会社 | Polymer conjugate of folic acid or folic acid derivative |
US8808749B2 (en) | 2009-05-15 | 2014-08-19 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of bioactive substance having hydroxy group |
KR20140024833A (en) | 2010-11-17 | 2014-03-03 | 니폰 가야꾸 가부시끼가이샤 | Novel polymer derivative of cytidine metabolism antagonist |
CA2847114C (en) | 2011-09-11 | 2018-08-21 | Nippon Kayaku Kabushiki Kaisha | Method for manufacturing block copolymer |
ES2628365T3 (en) | 2012-10-16 | 2017-08-02 | Janssen Pharmaceutica N.V. | Phenyl-linked quinolinyl modulators of ROR-GAMA-T |
LT2909192T (en) | 2012-10-16 | 2017-07-10 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of ror-gamma-t |
CA2888480C (en) | 2012-10-16 | 2021-03-16 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of ror.gamma.t |
US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
EP3057422B1 (en) | 2013-10-15 | 2019-05-15 | Janssen Pharmaceutica NV | Quinolinyl modulators of ror(gamma)t |
US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
KR20160070133A (en) | 2013-10-15 | 2016-06-17 | 얀센 파마슈티카 엔.브이. | Alkyl Linked Quinolinyl modulators of RORyt |
US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW349948B (en) * | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
CA2231105C (en) * | 1995-12-08 | 2005-09-13 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives |
TW591030B (en) * | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
ATE366250T1 (en) * | 1997-04-25 | 2007-07-15 | Janssen Pharmaceutica Nv | QUINAZOLINONES INHIBIT FARNESYL TRANSFERASE |
IL136462A0 (en) * | 1997-12-22 | 2001-06-14 | Schering Corp | Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases |
AU4562799A (en) * | 1998-06-15 | 2000-01-05 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6358985B1 (en) * | 1998-07-02 | 2002-03-19 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
JP4725940B2 (en) * | 1998-12-23 | 2011-07-13 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 1,2-Cyclic quinoline derivatives |
-
2001
- 2001-02-26 EP EP01913838A patent/EP1267871A2/en not_active Withdrawn
- 2001-02-26 JP JP2001563095A patent/JP2003525238A/en not_active Withdrawn
- 2001-02-26 CA CA002397256A patent/CA2397256A1/en not_active Abandoned
- 2001-02-26 AU AU2001239275A patent/AU2001239275A1/en not_active Abandoned
- 2001-02-26 WO PCT/EP2001/002167 patent/WO2001064198A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2001064198A2 (en) | 2001-09-07 |
WO2001064198A3 (en) | 2002-03-21 |
EP1267871A2 (en) | 2003-01-02 |
CA2397256A1 (en) | 2001-09-07 |
JP2003525238A (en) | 2003-08-26 |
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