CY1747A - Purine derivatives and their pharmaceutical use - Google Patents

Purine derivatives and their pharmaceutical use

Info

Publication number
CY1747A
CY1747A CY174794A CY174794A CY1747A CY 1747 A CY1747 A CY 1747A CY 174794 A CY174794 A CY 174794A CY 174794 A CY174794 A CY 174794A CY 1747 A CY1747 A CY 1747A
Authority
CY
Cyprus
Prior art keywords
pharmaceutical use
purine derivatives
purine
derivatives
pharmaceutical
Prior art date
Application number
CY174794A
Other languages
English (en)
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848423833A external-priority patent/GB8423833D0/en
Priority claimed from GB858510331A external-priority patent/GB8510331D0/en
Priority claimed from GB858520618A external-priority patent/GB8520618D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of CY1747A publication Critical patent/CY1747A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY174794A 1984-09-20 1994-06-03 Purine derivatives and their pharmaceutical use CY1747A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848423833A GB8423833D0 (en) 1984-09-20 1984-09-20 Compounds
GB858510331A GB8510331D0 (en) 1985-04-23 1985-04-23 Compounds
GB858520618A GB8520618D0 (en) 1985-08-16 1985-08-16 Compounds

Publications (1)

Publication Number Publication Date
CY1747A true CY1747A (en) 1994-06-03

Family

ID=27262464

Family Applications (1)

Application Number Title Priority Date Filing Date
CY174794A CY1747A (en) 1984-09-20 1994-06-03 Purine derivatives and their pharmaceutical use

Country Status (24)

Country Link
EP (1) EP0182024B1 (da)
JP (2) JPS6185388A (da)
KR (1) KR930006349B1 (da)
AT (1) AT389118B (da)
AU (1) AU589371B2 (da)
BG (1) BG61493B2 (da)
CA (1) CA1262899A (da)
CY (1) CY1747A (da)
CZ (1) CZ283721B6 (da)
DE (1) DE3582399D1 (da)
DK (1) DK167019B1 (da)
ES (1) ES8703876A1 (da)
FI (1) FI87564C (da)
GR (1) GR852272B (da)
HK (1) HK128693A (da)
HU (1) HU198934B (da)
IE (1) IE58141B1 (da)
MX (1) MX165116B (da)
MY (1) MY102473A (da)
NL (1) NL960006I1 (da)
NO (1) NO167572C (da)
NZ (1) NZ213528A (da)
PT (1) PT81160B (da)
WO (1) WO1987005604A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8406538D0 (sv) 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
GB8628826D0 (en) * 1986-12-02 1987-01-07 Beecham Group Plc Pharmaceutical products
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
ES2098219T3 (es) * 1987-08-01 1997-05-01 Beecham Group Plc Compuestos de purina y su preparacion.
GB8817270D0 (en) * 1988-07-20 1988-08-24 Beecham Group Plc Novel process
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
CA2009109A1 (en) * 1989-02-02 1990-08-02 John Hannah Antiviral acyclonucleosides and acyclonucleotides
JPH02247191A (ja) * 1989-02-02 1990-10-02 Merck & Co Inc 抗レトロウイルス剤としてのプリンおよびピリミジン非環状ヌクレオシドの環状モノホスフエート類
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
GB9004647D0 (en) * 1990-03-01 1990-04-25 Beecham Group Plc Pharmaceuticals
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
GB9201961D0 (en) 1992-01-30 1992-03-18 Smithkline Beecham Plc Pharmaceuticals
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
IL111138A (en) * 1993-10-05 1997-04-15 Smithkline Beecham Plc Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
GB9323403D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
GB9323404D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
US6683084B1 (en) 1993-11-12 2004-01-27 Novartis International Pharmaceutical Ltd. Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9407698D0 (en) 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
DE4420751A1 (de) * 1994-06-15 1995-12-21 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Lactamen
BR9509236A (pt) * 1994-10-05 1997-10-21 Chiroscience Ltd Compostos purina e guanina como inibidores de pnp
GB9504497D0 (en) 1995-03-07 1995-04-26 Smithkline Beecham Plc Pharmaceuticals
GB9600847D0 (en) * 1996-01-16 1996-03-20 Smithkline Beecham Plc Pharmaceuticals
US7279483B2 (en) 1996-02-07 2007-10-09 Novartis Ag Famciclovir monohydrate
ES2165020T3 (es) * 1996-02-07 2002-03-01 Novartis Int Pharm Ltd Monohidrato de famciclovir.
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
PT102030B (pt) * 1996-07-20 1999-04-30 Smithkline Beecham Plc Processo para a apreparacao dos compostos penciclovir ou famciclovir que sao utesi como agentes antivirais
CA2251481A1 (en) 1997-11-12 1999-05-12 Junichi Yasuoka Purine derivatives having cyclopropane ring
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
WO2004018470A2 (en) 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
AU2004206827A1 (en) 2003-01-14 2004-08-05 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
AU2006230269A1 (en) 2005-03-30 2006-10-05 Novartis Ag Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
GB2426247A (en) 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
WO2017029298A1 (en) 2015-08-17 2017-02-23 Sanovel Ilac Sanayi Ve Ticaret A.S. A topical antiviral composition
CN108473519A (zh) * 2015-12-08 2018-08-31 雷特罗芬公司 用于治疗神经疾病的环状磷酸酯和环状氨基磷酸酯
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW22283A1 (en) * 1982-10-14 1985-05-22 Wellcome Found Antiviral compounds
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
AU577303B2 (en) * 1983-08-18 1988-09-22 Novartis International Pharmaceutical Ltd 9-substituted-2-amino purines
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions

Also Published As

Publication number Publication date
IE58141B1 (en) 1993-07-14
NO874764D0 (no) 1987-11-16
EP0182024A2 (en) 1986-05-28
MY102473A (en) 1992-06-30
FI87564B (fi) 1992-10-15
PT81160B (pt) 1988-01-22
HU198934B (en) 1989-12-28
DK167019B1 (da) 1993-08-16
FI875059A (fi) 1987-11-16
JPH0625241A (ja) 1994-02-01
HUT47576A (en) 1989-03-28
AU589371B2 (en) 1989-10-12
CZ283721B6 (cs) 1998-06-17
PT81160A (en) 1985-10-01
KR930006349B1 (ko) 1993-07-14
JPS6185388A (ja) 1986-04-30
NO874764L (no) 1987-11-16
NL960006I2 (nl) 1996-09-02
GR852272B (da) 1986-01-21
ATA904286A (de) 1989-03-15
WO1987005604A1 (en) 1987-09-24
CS391591A3 (en) 1992-05-13
EP0182024A3 (en) 1989-03-08
CA1262899A (en) 1989-11-14
JPH0586792B2 (da) 1993-12-14
FI875059A0 (fi) 1987-11-16
EP0182024B1 (en) 1991-04-03
DK424685D0 (da) 1985-09-18
IE852307L (en) 1986-03-20
FI87564C (fi) 1993-01-25
MX165116B (es) 1992-10-27
AT389118B (de) 1989-10-25
HK128693A (en) 1993-11-26
NO167572B (no) 1991-08-12
BG61493B2 (bg) 1997-09-30
AU4756085A (en) 1986-03-27
ES547128A0 (es) 1987-03-01
NL960006I1 (nl) 1996-09-02
NO167572C (no) 1991-11-20
ES8703876A1 (es) 1987-03-01
DE3582399D1 (de) 1991-05-08
JPH0826021B2 (ja) 1996-03-13
NZ213528A (en) 1989-03-29
DK424685A (da) 1986-03-21

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